Pityriasis rosea as a cutaneous manifestation of COVID‐19 infection

Ehsani, Amir Hooshang; Nasimi, Maryam; Bigdelo, Zeinab

doi:10.1111/jdv.16579

Cited by 102 publications

(136 citation statements)

References 6 publications

(5 reference statements)

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“…Pityriasis rosea‐like cutaneous eruption has been reported in an adult patient from Tehran, Iran 40 . A digitate variant has been observed in an elderly man hospitalized because of severe COVID‐19 disease.…”

Section: Chickenpox‐like Rashmentioning

confidence: 96%

Cutaneous signs in COVID ‐19 patients: A review

Wollina

Karadağ

Rowland‐Payne

et al. 2020

Dermatologic Therapy

259

286

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Coronavirus disease pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the epithelium of the airways.With the increasing involvement of dermatologist in management of this crisis, cutaneous symptoms gained more and more attention. In this review, we will describe cutaneous symptoms of patients of all ages in association with COVID-19.We will focus on such disorders that are caused by direct action of SARS-CoV-2 on tissues, complement, and coagulation system and on nonspecific eruption of the systemic viral infection. Drug-induced reactions are only mentioned in the differential diagnoses. Although more systematic investigations are warranted, it becomes clear that some symptoms are clinical signs of a milder COVID-19 course, while others are a red flag for a more severe course. Knowledge of the cutaneous manifestations of COVID-19 may help in early diagnosis, triage of patients, and risk stratification.

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Section: Chickenpox‐like Rashmentioning

confidence: 96%

Cutaneous signs in COVID ‐19 patients: A review

Wollina

Karadağ

Rowland‐Payne

et al. 2020

Dermatologic Therapy

259

286

View full text Add to dashboard Cite

show abstract

“…Largely considered self-limited, pityriasis rosea manifests during human herpes virus reactivation. One report describes an erythematous and scaly annual plaque on the forearm starting 3 days after the onset of COVID-19 pneumonia, followed by generalized, pruritic papular and plaque-like lesions in a classic pityriasis rosea trailing collaret pattern [62]. A digitate papulosquamous, pityriasis rosea variant eruption was described in an elderly patient in another report [21].…”

Section: Pityriasis Roseamentioning

confidence: 99%

Cutaneous Manifestations in Adult Patients with COVID-19 and Dermatologic Conditions Related to the COVID-19 Pandemic in Health Care Workers

Mawhirt

Frankel

Diaz³

2020

Curr Allergy Asthma Rep

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Purpose of Review COVID-19 (coronavirus viral disease 2019), due to the novel SARS-CoV-2, may present with different types of cutaneous manifestations of varying pathophysiology. During the ongoing pandemic, publications reporting dermatologic findings in COVID-19 continue to emerge. Recent Findings Cutaneous vasculopathy and microthrombus-related changes including acral and sacral lesions, retiform purpura, livedo reticularis, and cutaneous vasculitis are notable findings in adult patients. Other exanthems include urticaria or angioedema, morbilliform/maculopapular exanthems, erythema multiforme, and vesicular eruptions. Increased recognition of these findings, especially those consistent with cutaneous microthrombi or vasculitis, is of particular importance. Additionally, occupational dermatologic disease related to extended personal protective equipment (PPE) use, such as skin damage and irritant or allergic contact dermatitis (ACD), represents another emerging problem amidst the pandemic. Summary In this review, we highlight the various cutaneous manifestations associated with COVID-19 in adult patients and occupational dermatitis in health care workers (HCWs) caring for this patient population. Keywords COVID-19. SARS-CoV-2. Cutaneous manifestations. Dermatologic. Rash. Contact dermatitis Abbreviations AAD American Academy of Dermatology ACD Allergic contact dermatitis ACE2 Angiotensin-converting enzyme 2 AD Atopic dermatitis AGEP Acute generalized exanthematous pustulosis ARDS Acute respiratory distress syndrome COVID-19 Coronarvirus viral disease 2019 CSSV Cutaneous small vessel vasculitis DIC Disseminated intravascular coagulation DiHS/DRESS Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms HCW Health care worker ICD Irritant contact dermatitis ITP Immune thrombocytopenic purpura PPE Personal protective equipment PT Patch test RT-PCR Reverse transcriptase polymerase chain reaction SARS-CoV-2 Severe acute respiratory distress syndrome coronavirus 2 SDRIFE Symmetrical drug-related intertriginous and flexural exanthema This article is part of the Topical Collection on Allergic Skin Diseases

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“…10 Ehsani et al reported a case of pityriasis rosea in a 27-year-old otherwise healthy male who was later diagnosed to have COVID-19. 11 It was confirmed that COVID-19 infection is accompanied by a reduction in lymphocytes, monocytes, and eosinophils, along with a significant reduction of CD4/CD8 T cells, B cells, and natural killer (NK) cells. It was further revealed that non-survivor COVID-19 patients continued to show a decrease in lymphocyte count along the course of their disease until death.…”

Section: Discussionmentioning

confidence: 90%