Pituitary adenoma consecrating GH and ACTH: A rare case report

Abstract

Plurihormonal Pituitary adenoma is defined as an adenoma that expresses more than one hormone on immunohistochemistry. The most common combination in these adenomas includes growth hormone (GH) and prolactin (PRL). We describe an interesting case of plurihormonal pituitary adenoma with double hormonal staining for adrenocorticotrophic hormone (ACTH) and GH in a patient who presented with acromegaly and subtle signs of Cushing disease due to a large pituitary macroadenoma