Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of children and adolescents

Kashbour, Wafa; Gupta, Puneet; Worthington, Helen V; Boyers, Dwayne

doi:10.1002/14651858.cd003067.pub5

Cited by 51 publications

(67 citation statements)

References 75 publications

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“…A recent Cochrane Library review compared fluoride varnish with sealants of different material types for different follow-up times to investigate their ability to prevent dental occlusal caries, and different results were found [85].…”

Section: Using Fluoride Varnish For Occlusal Caries Preventionmentioning

confidence: 99%

“…Two trials used a resin-modified glass ionomer [87,88]. It was not appropriate to conduct a meta-analysis because of the heterogeneity of the studies [85].…”

Section: Using Fluoride Varnish For Occlusal Caries Preventionmentioning

confidence: 99%

“…Four out of the five studies assessed the first permanent molars after a 2-3-year followup period and were subjected to a meta-analysis [46,[89][90][91]. The results of the meta-analysis were inconclusive as to whether fluoride varnishes are superior to resin fissure sealants in preventing occlusal caries or vice versa [85].…”

Section: Using Fluoride Varnish For Occlusal Caries Preventionmentioning

confidence: 99%

“…Additionally, sealants were reapplied if lost. Research authors declared that the study was done in a population with low caries risk [85].…”

Section: Using Fluoride Varnish For Occlusal Caries Preventionmentioning

confidence: 99%

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Fluoride Varnishes for Preventing Occlusal Dental Caries: A Review

et al. 2021

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Dental caries are most likely to occur on occlusal surfaces from the early eruptive stages of the tooth. In children, about 80% to 90% of dental caries are occlusal caries. Different preventive modalities are used to prevent occlusal caries. One of the methods used for occlusal caries prevention is fluoride varnish. A vast number of clinical trials have evaluated several types of sealant material and fluoride varnish to assess their ability to prevent occlusal caries in both primary and permanent dentition. The purpose of the current study was to provide an updated overview of the development, composition, mechanism of action, application, and safety of fluoride varnish, as well as its effect on occlusal caries prevention. This review of recently published studies on fluoride varnish and its effect on occlusal caries prevention shows that in children at moderate to high risk of caries, fluoride varnishes prevent occlusal caries. Both resin-based fissure sealants and fluoride varnish are effective for occlusal caries prevention for first-permanent molars. However, it was not possible to identify which one has the best effect. It is recommend that fluoride varnish is applied for children at high risk of caries two to four times per year.

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Section: Using Fluoride Varnish For Occlusal Caries Preventionmentioning

confidence: 99%

“…Two trials used a resin-modified glass ionomer [87,88]. It was not appropriate to conduct a meta-analysis because of the heterogeneity of the studies [85].…”

Section: Using Fluoride Varnish For Occlusal Caries Preventionmentioning

confidence: 99%

Section: Using Fluoride Varnish For Occlusal Caries Preventionmentioning

confidence: 99%

“…Additionally, sealants were reapplied if lost. Research authors declared that the study was done in a population with low caries risk [85].…”

Section: Using Fluoride Varnish For Occlusal Caries Preventionmentioning

confidence: 99%

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Fluoride Varnishes for Preventing Occlusal Dental Caries: A Review

et al. 2021

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“…Brenno Anderson Santiago Dias, Jefferson Lucas Mendes, Geovanna Caroline Brito da Silva, Layla Narrely Santos Alves, Francielly de Lemos Medeiros, Rodrigo Gadelha Vasconcelos, Marcelo Gadelha Vasconcelos A eficácia do selante resinoso está diretamente relacionada com sua capacidade retentiva, desse modo esse apresenta uma certa superioridade na retenção quando comparado com o selante ionomérico (KOBAYASHI et al, 2015; GONÇALVES et al, 2016; PRABAKAR et al, 2018; ALSABEK et al 2019.) Nesse sentido, é fundamental o domínio sobre a técnica de aplicação para seu sucesso clínico, tendo cuidado com o controle da umidade na região, impedindo ao máximo a contaminação do material por meio da saliva (AL-SUTANI et al, 2020)Assim, os selantes são materiais de primeira escolha em casos de prevenção de lesões cariosas, tendo melhor eficácia e durabilidade quando comparado com os vernizes fluoretados(KASHBOUR et al 2020). Ademais, estudos recentes comprovam que além do efeito preventivo do material selador, esse promove também a interrupção da lesão cariosa já instalada e a remineralização da estrutura afetada(ALVES et al, 2017;URQUHART et al, 2019).Brenno Anderson Santiago Dias, Jefferson Lucas Mendes, Geovanna Caroline Brito da Silva, Layla Narrely Santos Alves, Francielly de Lemos Medeiros, Rodrigo Gadelha Vasconcelos, Marcelo Gadelha Vasconcelos…”

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et al. 2021

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Noninferiority of Silver Diamine Fluoride vs Sealants for Reducing Dental Caries Prevalence and Incidence

Ruff,

Barry Godín,

Niederman

2024

JAMA Pediatr

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ImportanceDental caries is the world’s most prevalent noncommunicable disease and a source of health inequity; school dental sealant programs are a common preventive measure. Silver diamine fluoride (SDF) may provide an alternative therapy to prevent and control caries if shown to be noninferior to sealant treatment.ObjectiveTo determine whether school-based application of SDF is noninferior to dental sealants and atraumatic restorative treatment (ART) in the prevalence of dental caries.Design, Setting, and ParticipantsThe Silver Diamine Fluoride Versus Therapeutic Sealants for the Arrest and Prevention of Dental Caries in Low-Income Minority Children (CariedAway) study was a pragmatic noninferiority cluster-randomized clinical trial conducted from February 2018 to June 2023 to compare silver diamine fluoride vs therapeutic sealants for the arrest and prevention of dental caries. Children at primary schools in New York, New York, with at least 50% of the student population reporting as Black or Hispanic and at least 80% receiving free or reduced lunch were included. This population was selected as they are at the highest risk of caries in New York. Students were randomized to receive either SDF or sealant with ART; those aged 5 to 13 years were included in the analysis. Treatment was provided at every visit based on need, and the number of visits varied by child. Schools with preexisting oral health programs were excluded, as were children who did not speak English. Of 17 741 students assessed for eligibility, 7418 were randomized, and 4100 completed follow-up and were included in the final analysis.InterventionsParticipants were randomized at the school level to receive either a 38% concentration SDF solution or glass ionomer sealants and ART. Each participant also received fluoride varnish.Main Outcomes and MeasuresPrimary study outcomes were the prevalence and incidence of dental caries.ResultsA total of 7418 children (mean [SD] age, 7.58 [1.90] years; 4006 [54.0%] female; 125 [1.7%] Asian, 1246 [16.8%] Black, 3648 [49.2%] Hispanic, 153 [2.1%] White, 114 [1.5%] multiple races or ethnicities, 90 [1.2%] other [unspecified], 2042 [27.5%] unreported) were enrolled and randomized to receive either SDF (n = 3739) or sealants with ART (n = 3679). After initial treatment, 4100 participants (55.0%) completed at least 1 follow-up observation. The overall baseline prevalence of dental caries was approximately 27.2% (95% CI, 25.7-28.6). The odds of decay prevalence decreased longitudinally (odds ratio [OR], 0.79; 95% CI, 0.75-0.83) and SDF was noninferior compared to sealants and ART (OR, 0.94; 95% CI, 0.80-1.11). The crude incidence of dental caries in children treated with SDF was 10.2 per 1000 tooth-years vs 9.8 per 1000 tooth-years in children treated with sealants and ART (rate ratio, 1.05; 95% CI, 0.97-1.12).Conclusions and RelevanceIn this school-based pragmatic randomized clinical trial, application of SDF resulted in nearly identical caries incidence compared to dental sealants and ART and was noninferior in the longitudinal prevalence of caries. These findings suggest that SDF may provide an effective alternative for use in school caries prevention.Trial RegistrationClinicalTrials.gov Identifier: NCT03442309

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Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of children and adolescents

Abstract: Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of children and adolescents.

Cited by 51 publications

References 75 publications

Fluoride Varnishes for Preventing Occlusal Dental Caries: A Review

Fluoride Varnishes for Preventing Occlusal Dental Caries: A Review

Lipólise: Uma Revisão Bibliográfica

Noninferiority of Silver Diamine Fluoride vs Sealants for Reducing Dental Caries Prevalence and Incidence

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