Pishacha grahonmada – Frontotemporal dementia with Vitamin B<sub>12</sub> deficiency?

Mamidi, Prasad; Gupta, Kshama

doi:10.4103/ayuhom.ayuhom_23_21

Cited by 4 publications

(2 citation statements)

References 31 publications

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“…Additionally, up to 20% of people with TTM eat the hair they pull (trichophagia) [1]. This may result in the formation of gastrointestinal hairballs (trichobezoars), which have the potential to cause obstruction, warranting surgical intervention [1,11].…”

Section: Epidemiologymentioning

confidence: 99%

“…Given that many of the co-occurring disorders have established genetic underpinnings, it is plausible that genetic contributions may underlie TTM as well [11]. One study by Hemmings et al in 2006 explored the role that certain serotonergic and dopaminergic gene polymorphisms may play in the development of TTM by comparing gene variants between TTM, OCD, and control groups.…”

Section: Proposed Causes 21 Geneticmentioning

confidence: 99%

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A Review of Behavioral and Pharmacological Treatments for Adult Trichotillomania

Bennett,

Ryznar

2024

Psychology International

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Trichotillomania (TTM) is a psychiatric disorder involving chronic, recurrent urges to pull out one’s own hair, arising frequently in childhood and early adolescence. This disorder predominantly affects women and has a high co-morbidity with many other psychiatric conditions. Currently, the etiology is unknown, which makes treating TTM extremely difficult. While the epidemiology and proposed causes will be discussed briefly, the primary purpose of this review is to provide a comprehensive, updated summary of the psychological and pharmacological management options for patients diagnosed with TTM, as new clinical trial data for previously studied and novel treatments have become available within the last decade. Of the behavioral interventions, cognitive behavioral therapy (CBT) and habit reversal training (HRT) have demonstrated the greatest improvements in hair-pulling severity, with HRT showing the most efficacy for long-term maintenance of progress. Pharmacological therapies with the most success include Olanzapine, Clomipramine, and N-Acetylcysteine, though larger replication studies are needed. Selective serotonin reuptake inhibitors (SSRIs) have yielded inconsistent results in clinical trials, yet they are frequently prescribed for TTM. Naltrexone, Dronabinol, and Inositol are emerging as potential treatments, but the results suggest that additional studies are needed. Future research directions include larger placebo-controlled pharmacological trials, exploring the efficacy of combined behavioral and pharmacological approaches compared to monotherapy, and delving into the potential genetic and neurochemical contributions that may underlie TTM.

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Section: Epidemiologymentioning

confidence: 99%

Section: Proposed Causes 21 Geneticmentioning

confidence: 99%

A Review of Behavioral and Pharmacological Treatments for Adult Trichotillomania

Bennett,

Ryznar

2024

Psychology International

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Food cravings, disordered eating behaviour and alcohol abuse in Bhutonmadas - An exploratory review

Mamidi¹,

Gupta²

2023

JPCPY

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Various psychiatric and neuropsychiatric conditions are described under a broad disease entity called Unmada in Ayurvedic classical texts. Bhutonmada or Grahonmada is a specific type of Unmada that has multiple phenotypic clinical presentations. Bhutonmada is multifactorrial, heterogeneous, and idiopathic in nature. Different types of food cravings, abnormal eating behaviours and alcohol abuse related symptoms are mentioned in the literature of Bhutonamada. The present study is aimed to explore and analyze the clinical features of Bhutonmada related to food cravings, abnormal eating behaviours and alcohol abuse with the help of literature based on contemporary nutritional psychiatry. Abhipraayam, Ruchim, Priyam, Ratim, Sakta Drishtim and Yachinam are the various terms quoted in the context of Bhutonmada, represents variability of food cravings depend upon various factors such as intensity, frequency, quality, mood, inter-individual, and socio-cultural. Various abnormal or disordered eating behaviours such as hypophagia (Alpaahaara), hyperphagia (Bahvaashinam/Bahu Bhuk/ Bahusha Yachantam), emotional eating (Lolam), binge eating (Annapaana Ratim), strange eating habits (Bhramad Bhojinam) etc are mentioned in Bhutonmada literature. Appetite abnormalities such as Anannabhilasha, Arochaka, Na Kshuda, Kshudaatura etc manifests into either excessive (Bahvaashinam/ Bahu Bhuk) or low food consumption (Alpaahaara/Anna Dveshinam) are also described in the Bhutonmada context. Terms such as Abhiprayam, Ruchim, Priyam, Ratim and Sakta Drishtim pertaining to alcohol use/abuse in Bhutonmada could possess different contextual meanings. The present exploratory review will provide various new insights and better understanding of the terminology related to food cravings, eating disorders and alcohol use disorders in Bhutonmada and paves the way for the development of questionnaires and dietary or nutritional guidelines in the diagnostic and/or management protocols of Bhutonmada.

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Kleine − Levin syndrome: An ayurvedic perspective

Mamidi

Gupta

2022

Indian J Ayurveda lntegr Med

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Pishacha grahonmada – Frontotemporal dementia with Vitamin B₁₂ deficiency?

Cited by 4 publications

References 31 publications

A Review of Behavioral and Pharmacological Treatments for Adult Trichotillomania

A Review of Behavioral and Pharmacological Treatments for Adult Trichotillomania

Food cravings, disordered eating behaviour and alcohol abuse in Bhutonmadas - An exploratory review

Kleine − Levin syndrome: An ayurvedic perspective

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Pishacha grahonmada – Frontotemporal dementia with Vitamin B12 deficiency?

Cited by 4 publications

References 31 publications

A Review of Behavioral and Pharmacological Treatments for Adult Trichotillomania

A Review of Behavioral and Pharmacological Treatments for Adult Trichotillomania

Food cravings, disordered eating behaviour and alcohol abuse in Bhutonmadas - An exploratory review

Kleine − Levin syndrome: An ayurvedic perspective

Contact Info

Product

Resources

About

Pishacha grahonmada – Frontotemporal dementia with Vitamin B₁₂ deficiency?