Piper guineense Effects on Testicular Histoarchitecture

Abstract

Piper guineense is used as spice and herb, particularly to enhance libido. P. guineense has effects on penile erection and copulatory behaviour which are controlled by androgens. This study was carried out to evaluate the effects of consumption of P. guineense leaves on testicular histoarchitecture. The effects of P. guineense ingestion, in form of pelleted formulation, on the histoarchitecture of the testis of adult male Wistar rats were studied. Thirty adult male Wistar rats were divided into six groups labelled A-F. Group A animals served as the control and they were fed ad libitum throughout the experiment. Dried and powdered P. guineense leaf was added to the feed of the rats in Groups B, C, D, E and F in graded proportions. Based on the well monitored and properly evaluated rate of feed consumption, the proportion of P. guineense in the feed for Groups B, C, D, E and F gave approximate daily dosage of 100, 200, 300, 400 and 500 mg/kg body weight respectively. The regimen design was to observe the possible influence of dosage variations.

Effect of Coadministration of Lambda Cyhalothrin and Different Local Spices on Testicular Histology in Swiss Mice

“…Reports have revealed high incidence of reproductive dysfunction among the population especially the male counterparts. Some of the factors responsible for infertility are associated with hormonal secretion, erectile impotence, disorders of ejaculation, and toxic effects on the testes and accessory sex organs [3]. To achieve sexual quality, medicinal plants, spices, herbs, plant parts are commonly used for the treatment of male infertility associated disorders-aphrodisiacs [3,4,5] with little or no knowledge about their composition and possible side effect based on the dosage.…”

“…Some of the factors responsible for infertility are associated with hormonal secretion, erectile impotence, disorders of ejaculation, and toxic effects on the testes and accessory sex organs [3]. To achieve sexual quality, medicinal plants, spices, herbs, plant parts are commonly used for the treatment of male infertility associated disorders-aphrodisiacs [3,4,5] with little or no knowledge about their composition and possible side effect based on the dosage. Medicinal plants are rich sources of antioxidants, cost effective and potent alternative with few and transient side effects in the treatment and management of reproductive disorders, when compared with the existing conventional therapeutic drugs available in the market.…”