Pilomatricoma coexistent with epidermal cyst

Pujani, Mukta; Agarwal, Shilpi; Goyal, Ruchika; Jyotsna, P. Lalitha; Tejwani, Narender; Rautela, Archna

doi:10.1111/j.1365-4632.2010.04618.x

Cited by 4 publications

(1 citation statement)

References 3 publications

(5 reference statements)

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“…In rare cases, pilomatrixoma occurs as a hybrid lesion (20,21). For example, Terada reported on a mixed pilomatrixoma/epithelial cyst lesion with increased Ki67 expression that also expressed p53 (20).…”

Section: Discussionmentioning

confidence: 99%

Pilomatrixoma of the Neck/Shoulder Region Mimicking a Rapidly Growing Neoplasm of Peripheral Nerve Sheath Origin in Neurofibromatosis Type 1

Friedrich

Schüller

Hagel

2017

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Neurofibromatosis type 1 (NF1) is an autosomal dominant hereditary disorder. Neurofibroma is the most common neoplasm of this disease. This lesion is characterized by circumscribed soft or knotty skin tumors derived from peripheral nerve sheath cells. Numerous other neoplasms have been described for this tumor predisposition syndrome. This case report adds the diagnostic and therapeutic procedures in the case of an NF1 patient in whom the rapidly growing, nodular, subcutaneous tumor initially led to the suspicion of a malignant neoplasm. The tumor proved to be pilomatrixoma, which closely adhered to a neurofibroma.

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Section: Discussionmentioning

confidence: 99%

Pilomatrixoma of the Neck/Shoulder Region Mimicking a Rapidly Growing Neoplasm of Peripheral Nerve Sheath Origin in Neurofibromatosis Type 1

Friedrich

Schüller

Hagel

2017

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Pilomatrixoma: A Comprehensive Review of the Literature

Jones

Robertson

et al. 2018

The American Journal of Dermatopathology

116

176

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Pilomatrical carcinosarcoma of the temple: A case report

Mori¹

2019

J Cutan Pathol

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Pilomatrical carcinosarcoma is a very rare entity, with only six cases reported until now. This report describes the case of a 100-year-old woman with a mass on the left temple that had existed for several decades but had recently grown in size. Histology showed an asymmetric lesion composed of basaloid cells, spindle cells, and "shadow" or "ghost" cells. Cells had atypical hyperchromatic nuclei with prominent nucleoli, high mitotic activity, and atypical mitosis. In the central area, an epidermal cyst-like structure was seen. The diagnosis of pilomatrical carcinosarcoma was rendered. This case appeared to have arisen from malignant transformation of a pilomatricoma because of the long clinical history and existence of a benign epidermal cyst-like structure. In addition, the observation that the basaloid cells and spindle cells showed a gradual transition from one to the other and that both types were positive for β-catenin would seem to support a common clonal origin for the carcinomatous and sarcomatous components. K E Y W O R D S epidermal cyst, pilomatrical carcinosarcoma, pilomatricoma

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Pilomatricoma coexistent with epidermal cyst

Cited by 4 publications

References 3 publications

Pilomatrixoma of the Neck/Shoulder Region Mimicking a Rapidly Growing Neoplasm of Peripheral Nerve Sheath Origin in Neurofibromatosis Type 1

Pilomatrixoma of the Neck/Shoulder Region Mimicking a Rapidly Growing Neoplasm of Peripheral Nerve Sheath Origin in Neurofibromatosis Type 1

Pilomatrixoma: A Comprehensive Review of the Literature

Pilomatrical carcinosarcoma of the temple: A case report

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