Pigmented villonodular synovitis: MRI characteristics

Hughes, Tudor; Sartoris, David J.; Schweitzer, Mark E.; Resnick, Donald

doi:10.1007/bf02425937

Cited by 205 publications

(98 citation statements)

References 25 publications

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“…T 2 -weighted MR imaging of GCRG, GCT, and PVNS demonstrates extremely low intensity, 10,11,14,18,19,24,34,35) whereas the other tumors usually appear as high intensity. We consider that this finding is very important in the differential diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Giant Cell Reparative Granuloma of the Temporal Bone: Neuroradiological and Immunohistochemical Findings. Case Report.

Yoshimura

Onda

Tanaka

et al. 2002

Neurol. Med. Chir.(Tokyo)

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A 38-year-old man presented with a giant cell reparative granuloma (GCRG) of the left temporal bone. Computed tomography showed a osteolytic middle cranial mass lesion. Magnetic resonance (MR) imaging showed the lesion as low intensity with heterogeneous enhancement by gadolinium on the T 1 -weighted images, and extremely low intensity on the T 2 -weighted images. Angiography showed the lesion as highly vascular and fed by branches of the left external carotid artery. After preoperative embolization, gross total removal of the tumor was performed. The postoperative course was uneventful and no evidence of recurrence has been found for more than 4 years. Histological examination revealed GCRG with multinucleated giant cells in the fibrous background, abundant collagen bundles, hemosiderin deposits, and trabeculae of reactive bone. Some of the mononuclear stromal cells and almost all of the giant cells were positive for CD68, suggesting histiocytic differentiation. These histological features reflect the marked decrease in signal intensity on T 2 -weighted MR images.

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Section: Discussionmentioning

confidence: 99%

Giant Cell Reparative Granuloma of the Temporal Bone: Neuroradiological and Immunohistochemical Findings. Case Report.

Yoshimura

Onda

Tanaka

et al. 2002

Neurol. Med. Chir.(Tokyo)

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“…Previous terminology for PVNS included synovial xanthoma, synovial fibroendothelioma or endothelioma, benign fibrous histiocytoma, xanthomatous giant cell tumor of the tendon sheath, myeloplaxoma, chronic hemorrhagic villous synovitis, giant cell fibrohemangioma, fibrohemosideric sarcoma, sarcoma fusigiganocellulare, benign or malignant polymorphocellulartumor of the synovial membrane, and fibrous xanthoma of the synovial membrane. [11][12][13][14][15][16] The imaging findings of PVNS include: PLAIN RADIOGRAPH:Radiographic features are nonspecific, and radiographs may appear normal.The diffuse intra-articular form of PVNS oftendemonstrates a joint effusion and extrinsic erosionof bone on both sides of the joint, but thejoint space is unaffected. The localized formsof disease usually reveal only a soft-tissue mass.…”

Section: Discussionmentioning

confidence: 99%

Pigmented Villonodular Synovitis of Knee With Intra and Extra-Articular Presentation – A Case Report

J¹,

Nanna²,

P³

et al. 2013

jemds

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ABSTRACT:Pigmented villonodularsynovitis (PVNS) is a benign proliferative disorder primarily occurring in the large joints of the appendicular skeleton such as the knee and hip joints.PVNS is a slow-growing lesion of uncertain aetiology arising from the synovial membrane. It is characterized by villous and nodular overgrowths of the synovial membrane of the bursa or the tendon sheath.Though magnetic resonance imaging (MRI) is considered to be most sensitive in revealing findings consistent with PVNS, these findings are to be correlated with clinical and histopathological findings for precise diagnosis.Here we present a case with painless, non-traumatic swelling of left knee since 2 years, diagnosed as PVNS on plain radiograph, CT and MRI,underwent total synovectomy andwas later on confirmed histopathologically.

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“…Associated large joint effusion is common, but the cartilage is preserved and subchondral erosions may be seen only in late phases. Although, the defi nitive diagnosis is made by biopsy, the MR imaging fi ndings are virtually pathognomonic for pigmented villonodular synovitis [ 76 ].…”

Section: Pigmented Villonodular Synovitis (Pvns)mentioning

confidence: 99%