Piezoresistive MXene/Silk fibroin nanocomposite hydrogel for accelerating bone regeneration by Re-establishing electrical microenvironment

Hu, Zhichao; Lu, Jia-Qi; Zhang, Tai-Wei; Liang, Haifeng; Yuan, Hao; Su, Dihan; Ding, Wang; Lian, Ruixian; Ge, Yuxiang; Liang, Bing; Dong, Jian; Zhao, Xiaogang; Jiang, Libo

doi:10.1016/j.bioactmat.2022.08.025

Cited by 45 publications

(45 citation statements)

References 64 publications

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“…In Figure 2 c, which indicates the X-ray diffraction pattern of Ti 3 AlC 2 material, strong reflection peaks of 9.5° (002), 19.2° (004), 34.1° (101), 38.8° (008), 39.0° (104), and 41.8° (105) can be observed [ 42 ]. However, following HF etching, the etching of the Al layer and the embedding of the lithium-ion indicate the weakening of the characteristic peak of the Al element at 39.0° and the shift of the (002) to a smaller angle, demonstrating the successful preparation of MXene.…”

Section: Resultsmentioning

confidence: 99%

Flexible Stretchable, Dry-Resistant MXene Nanocomposite Conductive Hydrogel for Human Motion Monitoring

Liu

Gui

et al. 2023

Polymers

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Conductive hydrogels with high electrical conductivity, ductility, and anti-dryness have promising applications in flexible wearable electronics. However, its potential applications in such a developing field are severely hampered by its extremely poor adaptability to cold or hot environmental conditions. In this research, an “organic solvent/water” composite conductive hydrogel is developed by introducing a binary organic solvent of EG/H2O into the system using a simple one-pot free radical polymerization method to create Ti3C2TX MXene nanosheet-reinforced polyvinyl alcohol/polyacrylamide covalently networked nanocomposite hydrogels (PAEM) with excellent flexibility and mechanical properties. The optimized PAEM contains 0.3 wt% MXene has excellent mechanical performance (tensile elongation of ~1033%) and an improved modulus of elasticity (0.14 MPa), a stable temperature tolerance from −50 to 40 °C, and a high gauge factor of 10.95 with a long storage period and response time of 110 ms. Additionally, it is worth noting that the elongation at break at −40 °C was maintained at around 50% of room temperature. This research will contribute to the development of flexible sensors for human-computer interaction, electronic skin, and human health monitoring.

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Section: Resultsmentioning

confidence: 99%

Flexible Stretchable, Dry-Resistant MXene Nanocomposite Conductive Hydrogel for Human Motion Monitoring

Liu

Gui

et al. 2023

Polymers

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“…32 Besides, interactions between MXene and SF chains form via hydrogen bonds. 32 Besides, as one of the two-dimensional transition metal carbides, MXene exhibits a superior metallic negative thermal coefficient (NTC) behavior and could function the Hygel as an excellent temperature sensor. 33 For FA-CaCl 2 , the acid hydrolysis effect could dissolve silk while preserving its nanofibril structure.…”

Section: Hyper-attribute Hygelmentioning

confidence: 99%

Water-Modulated Biomimetic Hyper-Attribute-Gel Electronic Skin for Robotics and Skin-Attachable Wearables

et al. 2023

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Electronic skin (e-skin), mimicking the physical–chemical and sensory properties of human skin, is promising to be applied as robotic skins and skin-attachable wearables with multisensory functionalities. To date, most e-skins are dedicated to sensory function development to mimic human skins in one or several aspects, yet advanced e-skin covering all the hyper-attributes (including both the sensory and physical–chemical properties) of human skins is seldom reported. Herein, a water-modulated biomimetic hyper-attribute-gel (Hygel) e-skin with reversible gel–solid transition is proposed, which exhibits all the desired skin-like physical–chemical properties (stretchability, self-healing, biocompatibility, biodegradability, weak acidity, antibacterial activities, flame retardance, and temperature adaptivity), sensory properties (pressure, temperature, humidity, strain, and contact), function reconfigurability, and evolvability. Then the Hygel e-skin is applied as an on-robot e-skin and skin-attached wearable to demonstrate its highly skin-like attributes in capturing multiple sensory information, reconfiguring desired functions, and excellent skin compatibility for real-time gesture recognition via deep learning. This Hygel e-skin may find more applications in advanced robotics and even skin-replaceable artificial skin.

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“…Mxene’s mechanical flexibility, hydrophilicity, and biocompatibility contribute to its use as a material for biomedical applications, including in tissue engineering, drug delivery [ 84 , 85 ], bioimaging, sensors, and as an antibacterial [ 86 ]. Regarding tissue engineering, MXene can be used as a material mainly for bone tissue engineering [ 87 , 88 ], myocardial tissue engineering [ 89 ], and nerve tissue engineering [ 90 ]. MXene/PLLa-PHA composite nanofibers prepared through electrospinning and the doping strategy were used as a smart biomaterial for cell cultures.…”

Section: Other Emerging Applications Of Mxenementioning

confidence: 99%

MXene-Based Nanomaterials for Multifunctional Applications

et al. 2023

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MXene is becoming a “rising star” material due to its versatility for a wide portfolio of applications, including electrochemical energy storage devices, electrocatalysis, sensors, biomedical applications, membranes, flexible and wearable devices, etc. As these applications promote increased interest in MXene research, summarizing the latest findings on this family of materials will help inform the scientific community. In this review, we first discuss the rapid evolutionary change in MXenes from the first reported M2XTx structure to the last reported M5X4Tx structure. The use of systematically modified synthesis routes, such as foreign atom intercalation, tuning precursor chemistry, etc., will be further discussed in the next section. Then, we review the applications of MXenes and their composites/hybrids for rapidly growing applications such as batteries, supercapacitors, electrocatalysts, sensors, biomedical, electromagnetic interference shielding, membranes, and flexible and wearable devices. More importantly, we notice that its excellent metallic conductivity with its hydrophilic nature distinguishes MXene from other materials, and its properties and applications can be further modified by surface functionalization. MXene composites/hybrids outperform pristine MXenes in many applications. In addition, a summary of the latest findings using MXene-based materials to overcome application-specific drawbacks is provided in the last few sections. We hope that the information provided in this review will help integrate lab-scale findings into commercially viable products.

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Piezoresistive MXene/Silk fibroin nanocomposite hydrogel for accelerating bone regeneration by Re-establishing electrical microenvironment

Cited by 45 publications

References 64 publications

Flexible Stretchable, Dry-Resistant MXene Nanocomposite Conductive Hydrogel for Human Motion Monitoring

Flexible Stretchable, Dry-Resistant MXene Nanocomposite Conductive Hydrogel for Human Motion Monitoring

Water-Modulated Biomimetic Hyper-Attribute-Gel Electronic Skin for Robotics and Skin-Attachable Wearables

MXene-Based Nanomaterials for Multifunctional Applications

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