Piezoresistive Microcantilevers-Based Cocaine Biosensors

Three different signal amplification strategies for the impedimetric sandwich detection of thrombin

“…Among aptasensors, different transduction techniques can be used; optical (Lee and Walt 2000), atomic force microscope (Basnar et al 2006), surface plasmon resonance (Vasilescu et al 2013), electrochemical (Ocaña et al 2012;Radi et al 2005) and piezoelectric (Srijanto et al 2012). In the last years, among the different electrochemical techniques reported, the use of electrochemical impedance spectroscopy (EIS) has grown among the examinated literature (McDonald 1987).…”

Preparation of novel optical fibre-based Cocaine sensors using a molecular imprinted polymer approach

“…Limited sensing solutions for Cocaine detection (e.g. aptamer-based biosensors [8][9][10][11]) are in existence but a compact, hand-held monitor utilising stable synthetic molecular receptors does not exist. This set of technologies includes aptamer-based electrochemical detection [8,9], aptamercoated, piezoresistive, microcantilever-based biosensing [10] and an electrogenerated chemiluminescence aptamer-based approach [11].…”

“…aptamer-based biosensors [8][9][10][11]) are in existence but a compact, hand-held monitor utilising stable synthetic molecular receptors does not exist. This set of technologies includes aptamer-based electrochemical detection [8,9], aptamercoated, piezoresistive, microcantilever-based biosensing [10] and an electrogenerated chemiluminescence aptamer-based approach [11]. In addition, Hans and Sigrist [12] are developing a sensor for detecting Cocaine in saliva and high affinity MIP nanoparticles [13] and extraction MIPs [14] for Cocaine have been reported.…”

Design and synthesis of a fluorescent molecular imprinted polymer for use in an optical fibre-based cocaine sensor

“…Sensing solutions for Cocaine detection have been reported, e.g. aptamer-based biosensors [4][5][6][7] and sensors for saliva, 8 but development of a compact, hand-held monitor utilising stable synthetic molecular receptors remains of interest for some specific applications. Optical fibre sensors can provide many advantages over other sensing technologies and these include their lightweight nature, low cost, potential for multiplexing, remote sensing capability, immunity to electromagnetic interference and overall robustness.…”