Phytopharmaceuticals: A new drug class regulated in India

Bhatt, Arun

doi:10.4103/2229-3485.179435

Cited by 47 publications

(24 citation statements)

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“…While the use of HMs for the above described indications is not country specific, some indications for HM use were more prominent within particular regions. For example, pregnant women in India and Ghana were more likely to use HMs to prevent miscarriage and improve the health status of the unborn baby than their counterparts in the developed nations (Adusi-Poku et al, 2015;Bhatt, 2016). Common fetal-related indications were an improvement of fetal physical and mental growth (Rahman et al, 2008;Adusi-Poku et al, 2015;Mugomeri et al, 2015;Bhatt et al, 2016;Dika et al, 2017), prevention of neonatal hyperbilirubinemia (Tabatabaee, 2011), or even protecting the unborn baby from evil (Maputle et al, 2015).…”

Section: Consumption Of Hms By Pregnant Womenmentioning

confidence: 99%

Use of Herbal Medicine by Pregnant Women: What Physicians Need to Know

et al. 2020

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About 80% of the consumers worldwide use herbal medicine (HMs) or other natural products. The percentage may vary significantly (7%-55%) among pregnant women, depending upon social status, ethnicity, and cultural traditions. This manuscript discusses the most common HMs used by pregnant women, and the potential interactions of HMs with conventional drugs in some medical conditions that occur during pregnancy (e.g., hypertension, asthma, epilepsy). It also includes an examination of the characteristics of pregnant HM consumers, the primary conditions for which HMs are taken, and a discussion related to the potential toxicity of HMs taken during pregnancy. Many cultures have used HMs in pregnancy to improve wellbeing of the mother and/or baby, or to help decrease nausea and vomiting, treat infection, ease gastrointestinal problems, prepare for labor, induce labor, or ease labor pains. One of the reasons why pregnant women use HMs is an assumption that HMs are safer than conventional medicine. However, for pregnant women with pre-existing conditions like epilepsy and asthma, supplementation of conventional treatment with HMs may further complicate their care. The use of HMs is frequently not reported to healthcare professionals. Providers are often not questioning HM use, despite little being known about the HM safety and HM-drug interactions during pregnancy. This lack of knowledge on potential toxicity and the ability to interact with conventional treatments may impact both mother and fetus. There is a need for education of women and their healthcare professionals to move away from the idea of HMs not being harmful. Healthcare professionals need to question women on whether they use any HMs or natural products during pregnancy, especially when conventional treatment is less efficient and/or adverse events have occurred as herbaldrug interactions could be the reason for these observations. Additionally, more preclinical and clinical studies are needed to evaluate HM efficacy and toxicity.

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Section: Consumption Of Hms By Pregnant Womenmentioning

confidence: 99%

Use of Herbal Medicine by Pregnant Women: What Physicians Need to Know

et al. 2020

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“…1 Phytopharmaceutical drugs are also known as herbal medicinal products. 2 According to U.S. Food and Drug Administration Botanical Drug Development Guidance, a botanical product could be classified as a food (including a dietary supplement), drug (including a biological drug), medical device, or cosmetic under the Federal Food, Drug, and Cosmetic Act. 3 According to European Union legislation, the term ''herbal medicinal products'' are any medicine that contains a herbal base, one or more herbal preparations, or one or more of these herbal substances in combination with one or more such herbal preparations (DIRECTIVE 2004/24/EC).…”

Section: Phytopharmaceuticals In the Modulation Of Human Behaviormentioning

confidence: 99%

Autism Spectrum Disorders: Potential Neuro-Psychopharmacotherapeutic Plant-Based Drugs

Urdaneta

Castillo

Montiel

et al. 2018

ASSAY and Drug Development Technologies

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Over the years, scientific researches have validated the healing benefits of many psychopharmacotherapeutic plant-based drugs to ameliorate psychiatric disorders. In contrast, the use of chemical procedures to isolate and purify specific compounds from plants that have been used to treat autism spectrum disorders (ASDs) and its clinical features may contribute to improve the quality of life of many patients. Also, herbal pharmacological treatments could improve the core symptoms of autism with fewer side effects. This review will focus on the uses and actions of phytopharmaceuticals in the behavioral conditions of ASDs. A large number of natural compound-based plant drugs have been tested in murine models of autism and in clinical trials with remarkable success in reversing the core and associated behaviors with autism such as flavonoids, cannabinoids, curcuminoids, piperine, resveratrol, and bacosides. This plant-based drug alternative is safer given that many psychiatric disorders and neurodegenerative pathologies do not often respond well to currently prescribed medications or have significant side effects. However, it is noteworthy to consider the need for large clinical trials to determine safety and efficacy. Many results are based on case reports or small size samples, and often the studies are open label. Standardization of procedures (i.e., purity and concentrations) and quality controls are strictly required to ensure the absence of side effects.

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“…Although some herbal preparations are very popular in our society, very few plant-based preparations have been scientifically evaluated and validated for their potential as medical treatments. In most countries herbal drugs are poorly regulated and their safety remains a major concern [6]. However, a promising field in the current therapies based on plant-derived compounds is the study of their synergistic activity when administered in combination with synthetic anticancer medications [7].…”

Section: Introductionmentioning

confidence: 99%

Immune system activation by natural products and complex fractions: a network pharmacology approach in cancer treatment

Gomez-Cadena¹,

Barreto²,

Fioretino³

et al. 2020

CST

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Natural products and traditional herbal medicine are an important source of alternative bioactive compounds but very few plant-based preparations have been scientifically evaluated and validated for their potential as medical treatments. However, a promising field in the current therapies based on plant-derived compounds is the study of their immunomodulation properties and their capacity to activate the immune system to fight against multifactorial diseases like cancer. In this review we discuss how network pharmacology could help to characterize and validate natural single molecules or more complex preparations as promising cancer therapies based on their multitarget capacities.

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Phytopharmaceuticals: A new drug class regulated in India

Cited by 47 publications

References 1 publication

Use of Herbal Medicine by Pregnant Women: What Physicians Need to Know

Use of Herbal Medicine by Pregnant Women: What Physicians Need to Know

Autism Spectrum Disorders: Potential Neuro-Psychopharmacotherapeutic Plant-Based Drugs

Immune system activation by natural products and complex fractions: a network pharmacology approach in cancer treatment

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