Phytochemistry, Pharmacology, and Toxicity of an Epiphytic Medicinal Shrub Viscum album L. (White Berry Mistletoe)

Majeed, Mahak; Rehman, Reiaz Ul

doi:10.1007/978-3-030-58975-2_12

Cited by 6 publications

(10 citation statements)

References 59 publications

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“…This was considered during the alcohol extraction of mistletoe (Japanese and European). When executed on cats, European and Japanese mistletoe showed lower blood pressure (Majeed & Rehman, 2021). Similar hypotensive results of mistletoe were shown in other animal experimental studies reported by other researchers.…”

Section: European Mistletoesupporting

confidence: 89%

Treatment of Hypertension by Using Natural Herbs and their Mechanism of Action

Aloufi¹,

Atwan²,

Alshammari³

2022

J Biochem Technol

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Section: European Mistletoesupporting

confidence: 89%

Treatment of Hypertension by Using Natural Herbs and their Mechanism of Action

Aloufi¹,

Atwan²,

Alshammari³

2022

J Biochem Technol

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“…In many parts of the world, Viscum spp. have been consumed for a long period of time as an herbal tea and as a supplement to health care [ 8 ]. Furthermore, Viscum spp.…”

Section: Health Benefits Of Viscum Species In Live...mentioning

confidence: 99%

“…found in southern Africa include V. verrucosum, V. rotundifolium, V. anceps, V. songimveloensis , and V. combreticola [ 5 , 6 , 7 ]. They are fodder resources for ruminants, especially during dry periods when good quality forage is scarce [ 8 ]. Öztürk et al [ 3 ] highlighted that the Viscum species extract nutrients and water from their host; hence, they are a rich fodder resource for ruminants.…”

Section: Introductionmentioning

confidence: 99%

Utilization of the Viscum Species for Diet and Medicinal Purposes in Ruminants: A Review

Hawu

Ravhuhali

Musekwa

et al. 2022

Animals

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A cost-effective, alternative protein and mineral source such as the Viscum species can be key to livestock production. Viscum spp. are used as feed in many semi-arid and arid regions globally, particularly during feed shortages. The species’ feeding value, and their pharmaceutical attributes, have been recognized worldwide, albeit with variation in nutritive value from one host to another. The antinutritional factors found in Viscum spp. may benefit livestock when consumed in moderation due to their immunomodulatory, proapoptotic, and antimicrobial properties. The Vachellia species are known to be the common hosts for Viscum spp. Further, even though Viscum spp. inhibit host tree development by reducing carbon absorption and the host tree’s carbohydrates, the efforts to regulate their infestation should not result in the plant’s total eradication due to the benefits to livestock (as well as in fodder and medicine). This review will help to improve understanding of Viscum species control measures, while also increasing the productivity of ruminants.

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“…Various research reported a large number of phytochemicals, such as lectins (glycopeptides), viscotoxins, terpenoids, coumarins, flavonoids, peptides, carbohydrates, sterols, alkaloids, proteins, amines, polyphenols, amino acids, and lignans [ 6 , 7 , 8 , 9 , 10 , 11 , 12 ]. These compounds were studied extensively to establish a relationship between antitumor activity and their biological properties.…”

Section: Introductionmentioning

confidence: 99%

“…It has also been found that the antitumor activity of particular metabolites isolated from viscum is much lower than that of the extract itself. It is due to the synergistic action by which metabolites act [ 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Romanian Viscum album L.—Untargeted Low-Molecular Metabolomic Approach to Engineered Viscum–AuNPs Carrier Assembly

Segneanu

Marin

Herea

et al. 2022

Plants

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Viscum is one of the most famous and appreciated medicinal plants in Europe and beyond. The symbiotic relationship with the host tree and various endogenous and ecological aspects are the main factors on which the viscum metabolites’ profiles depend. In addition, European traditional medicine mentions that only in two periods of the year (summer solstice and winter solstice) the therapeutic potential of the plant is at its maximum. Many studies have investigated the phytotherapeutic properties of viscum grown on different species of trees. However, studies on Romanian viscum are relatively few and refer mainly to the antioxidant and antiproliferative activity of mistletoe grown on Acer campestre, Fraxinus excelsior, Populus nigra, Malus domestica, or Robinia pseudoacacia. This study reports the first complete low-molecular-weight metabolite profile of Romanian wild-grown European viscum. A total of 140 metabolites were identified under mass spectra (MS) positive mode from 15 secondary metabolite categories: flavonoids, amino acids and peptides, terpenoids, phenolic acids, fatty acids, organic acids, nucleosides, alcohols and esters, amines, coumarins, alkaloids, lignans, steroids, aldehydes, and miscellaneous. In addition, the biological activity of each class of metabolite is discussed. The development of a simple and selective phyto-engineered AuNPs carrier assembly is reported and an evaluation of the nanocarrier system’s morpho-structure is performed, to capitalize on the beneficial properties of viscum and AuNPs.

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Phytochemistry, Pharmacology, and Toxicity of an Epiphytic Medicinal Shrub Viscum album L. (White Berry Mistletoe)

Cited by 6 publications

References 59 publications

Treatment of Hypertension by Using Natural Herbs and their Mechanism of Action

Treatment of Hypertension by Using Natural Herbs and their Mechanism of Action

Utilization of the Viscum Species for Diet and Medicinal Purposes in Ruminants: A Review

Romanian Viscum album L.—Untargeted Low-Molecular Metabolomic Approach to Engineered Viscum–AuNPs Carrier Assembly

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