Phytochemicals as Sources of Drugs

Ezzat, Shahira M.; Jeevanandam, Jaison; Egbuna, Chukwuebuka; Kumar, Shashank; Ifemeje, Jonathan C.

doi:10.1007/978-981-13-6920-9_1

Cited by 18 publications

(5 citation statements)

References 115 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The result obtained for the preliminary phytochemicals screening revealed the presence of flavonoids, alkaloids, saponins, phenols, tannins, and cardiac glycosides in all the four beans aqueous extract (Table 2). The presence of these phytochemicals is an indication that these local bean species can serve as a valuable source for the discovery of novel bioactive compounds for drug discovery (Egbuna and Ifemeje, 2015;Egbuna and Ifemeje, 2017;Arul et al, 2018;Tijjani et al, 2018;Ezzat et al, 2019;Kavitha et al, 2019;Nwosu et al, 2019;Srivastav et al, 2019). The quantitative analysis revealed that P. vulgaris L 'Red kidney' had the highest flavonoids (4.44±0.11 a %), alkaloids (4.85±0.01 a %), cardiac glycosides (10.41±0.93 a %) and haemaglutinin (0.78±0.00 a mg/l) (Table 3).…”

Section: Discussionmentioning

confidence: 99%

Effects of Four Local Species of Beans Consumed in South-eastern Nigeria on Selected Biochemical Indices of Wistar Albino Rats

Ifemeje

Egbuna

Uche

et al. 2021

IPS Interdiscip J Bio Sci

Self Cite

View full text Add to dashboard Cite

The chemical composition and the effects of four local species of beans on the liver and kidney function of Wistar albino rats were examined. The four beans species are Cajanus Cajan, Vigna unguiculata subsp. sesquipedalis, Phaseolus vulgaris L ‘Red kidney’, and Phaseolus vulgaris 'Black turtle’. The results obtained for the proximate composition analysis revealed that the protein content of the bean species was higher in P. vulgaris L ‘Red kidney’ (18.54±0.01a %), and P. vulgaris 'Black turtle’ (18.36±0.01a %) with no significant difference at P< 0.05. The phytochemical composition analysis revealed that the beans contain various phytochemicals including some anti-nutritional factors. The mineral composition analysis shows that V. u. subsp. Sesquipedalis had a higher level of minerals (4.80±4.43a mg/100g) followed by C. cajan (3.24±2.64b mg/100g). The experimental design comprises of 30 male Wistar albino rats distributed into 5 groups of 6 rats each. Each group except the control received 50g of normal rat feed + 100g of beans body weight. The effects of the beans species on the biochemical parameters suggest no adverse effects when compared to the control. Despite that, these beans contain high nutritional components that are of nutritional interest as as well as some anti-nutritional factors.

show abstract

Section: Discussionmentioning

confidence: 99%

Effects of Four Local Species of Beans Consumed in South-eastern Nigeria on Selected Biochemical Indices of Wistar Albino Rats

Ifemeje

Egbuna

Uche

et al. 2021

IPS Interdiscip J Bio Sci

Self Cite

View full text Add to dashboard Cite

show abstract

“…Chapters 16 , 18–21 of this book presents the various food sources of these nutrients. Also, the Editor of this book and his collaborating team has worked on many related projects especially as it regards drug discovery from natural products [ [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] ].…”

Section: Future Perspectivesmentioning

confidence: 99%

Pathogenesis and mutagenesis of SARS-CoV-2

Egbuna

Archibong

Mansoor

et al. 2022

Coronavirus Drug Discovery

Self Cite

View full text Add to dashboard Cite

“…Again, the authors recommended that efforts should be directed to natural products especially medicinal plants with potent antiviral, immunomodulating, and anti-inflammatory properties. Many collections of Egbuna and his collaborating team have presented the sources for these compounds in their books and book chapters [ [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] ].…”

Section: Future Projectionsmentioning

confidence: 99%