Phytochemicals and Biological Activities of Laurel Tree (<i>Laurus nobilis</i>)

Alejo-Armijo, Alfonso; Altarejos, Joaquı́n; Salido, Sofı́a

doi:10.1177/1934578x1701200519

Cited by 40 publications

(66 citation statements)

References 184 publications

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“…The qualitative examination revealed the presence of significant amounts of polyphenols and flavonoids (Table 3). Notably, this finding conforms to the report by Chandra et al [42] and Alejo-Armijo et al [43] who revealed the existence of these active constituents in both extracts. It has been shown that all these secondary metabolites have many therapeutic properties and are known to be pharmacologically active components.…”

Section: Discussionsupporting

confidence: 93%

Gas chromatography-mass spectrometry analysis, phytochemical screening and antiprotozoal effects of the methanolic Viola tricolor and acetonic Laurus nobilis extracts

Batiha

Beshbishy

Alkazmi

et al. 2020

BMC Complement Med Ther

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Background: The antiprotozoal and antioxidant activities of Viola tricolor and Laurus nobilis have been reported recently. Thus, the existing study pursued to assess the growth inhibition effect of methanolic extract of V. tricolor (MEVT) and acetonic extract of L. nobilis (AELN) against five Babesia parasites and Theileria equi in vitro and in vivo. Results: MEVT and AELN suppressed Babesia bovis, B. bigemina, B. divergens, B. caballi, and T. equi growth at halfmaximal inhibitory concentration (IC 50) values of 75.

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Section: Discussionsupporting

confidence: 93%

Gas chromatography-mass spectrometry analysis, phytochemical screening and antiprotozoal effects of the methanolic Viola tricolor and acetonic Laurus nobilis extracts

Batiha

Beshbishy

Alkazmi

et al. 2020

BMC Complement Med Ther

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“…During time laurel gained a considerable importance in traditional medicine [ 13 ] and its leaf extracts or EO were used as gastroprotective and antidiarrheal [ 14 , 15 ], analgesic and anti-inflammatory [ 16 ], as antidiabetic and to decrease the risk factors of cardiovascular diseases [ 17 , 18 ]. The cytotoxic, antibacterial and antioxidant activities were also investigated, and different authors reported anticancer, antioxidant, insecticidal and molluscidal, antidiabetic, antimicrobial and antifungal activities by L. nobilis [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

Laurus nobilis, Salvia sclarea and Salvia officinalis Essential Oils and Hydrolates: Evaluation of Liquid and Vapor Phase Chemical Composition and Biological Activities

Ovidi

Masci

Zambelli

et al. 2021

Plants

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Laurus nobilis, Salvia officinalis and Salvia sclarea essential oils (EOs) and hydrolates (HYs) were investigated to define their chemical compositions and biological properties. Gas-chromatography/Mass-spectrometry (GC/MS) and Headspace-GC/MS (HS-GC/MS) techniques were used to characterize the liquid and vapor phase chemical composition of EOs and HYs. 1,8-Cineole (42.2%, 33.5%) and α-pinene (16.7%, 39.0%) were the main compounds of L. nobilis EO; 1,8-cineole (30.3%, 48.4%) and camphor (17.1%, 8.7%) were for S. officinalis EO; linalyl acetate (62.6%, 30.1%) and linalool (11.1%, 28.9%) were for S. sclarea EO for the liquid and vapor phase, respectively. Chemical profile of HYs was characterized by 1,8-cineole (65.1%, 61.4%) as a main constituent of L. nobilis and S. officinalis HYs, while linalool (89.5%) was the main constituent of S. sclarea HY. The antioxidant activity of EOs and HYs was carried out by DPPH and ABTS assays and antimicrobial properties were also investigated by microdilution and the disc diffusion method for liquid and vapor phase against five different bacterial strains such as Escherichia coli ATCC 25922, Pseudomonas fluorescens ATCC 13525 and Acinetobacter bohemicus DSM 102855 among Gram-negative and Bacillus cereus ATCC 10876 and Kocuria marina DSM 16420 among Gram-positive. L. nobilis and S. officinalis EOs demonstrated considerable antibacterial activity, while S. sclarea EO proved to be less effective. Agar diffusion method and vapor phase test showed the EOs activity with the biggest halo inhibition diameters against A. bohemicus and B. cereus. A remarkably high antioxidant activity was determined for L. nobilis showing low EC50 values and also for S. sclarea; good EO results were obtained in both of the used assays. S. officinalis EC50 values were slightly higher to which corresponds to a lower antioxidant activity. Concerning the HYs, the EC50 values for L. nobilis, S. officinalis and S. sclarea were remarkably high corresponding to an extremely low antioxidant activity, as also obtained by expressing the values in Trolox equivalent antioxidant capacity (TEAC).

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“…SLs are the most common allergens in bay leaf, while on the molecular level, the exocyclic α‐methylene group of SLs is the target for the allergic reaction, and is also responsible for the cross‐reactions to Compositae plants 4‐6 . Our patient was negative to SL mix; nevertheless, allergy to SL could not be ruled out as in Laurus nobilis chemovars exist which contain SLs different from the ones in the commercially available SL hapten mix 7 …”

Section: Discussionmentioning

confidence: 75%