Phytochemical Study on the Essential Oils of Tarragon (Аrtemisia dracunculus L.) Growing in Tajikistan and Its Comparison With the Essential Oil of the Species in the Rest of the World

Abstract

The aerial parts of the tarragon ( Artemisia dracunculus) were collected around Kukteppa village, Ziddi, Varzob region of Tajikistan. The essential oil of tarragon was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry. Forty-five compounds representing 99.8% of total oil were identified. Sabinene (29.1%), estragole (24.6%), limonene (7.8%), ( Z)-artemidin (4.9%), myrcene (4.8%), and ( E)-β-ocimene (4.0%) were components with a representation higher than 4% of the essential oils of aerial parts of tarragon. Hierarchical cluster analysis of А. dracunculus essential oils on the global phytogeographic origin based on 30 essential oil components and 105 samples (globally) of this species, indicated the existence of its 7 major chemotypes: ocimene, α-terpinene, capillene, methyl eugenol, mixed chemotype, ( Z)-artemidin, and estragol chemotypes. The essential oils of А. dracunculus showed weak antioxidant and antibacterial activities. To our best knowledge, this is the first report concerning the chemical composition, chemotypic variation, antioxidant, and antimicrobial activities of the essential oils obtained from the aerial parts of А. dracunculus, growing wild in the Varzob region of Tajikistan.

Artemisia dracunculus (Tarragon): A Review of Its Traditional Uses, Phytochemistry and Pharmacology

“…The biosynthesis of these compounds begins at an early stage of plant development; therefore, in three-month-old specimens, the coumarin content may even reach 1.3%. The maximum level of this group of compounds has been found in five-year-old plants (Aglarova et al, 2008;Bhutia and Valant-vetschera, 2008;Obolskiy et al, 2011;Talbi et al, 2016;Mumivand et al, 2017;Bussmann et al, 2020;Sharopov et al, 2020).…”

“…25%), and elemicin (up to 57%) (Figure 1). Other compounds present in the oil in concentrations greater than 10% are: terpinen-4-ol, β-ocimene, cis-ocimene, α-trans-ocimene, limonene and trans-anethole, α-phellandrene, β-phellandrene (Z)-artemidin, capillene (Table 1) (Aglarova et al, 2008;Ayoughi et al, 2011;Obolskiy et al, 2011;Tak et al, 2014;Karimi et al, 2015;Abdollahnejad et al, 2016;Hassanzadeh et al, 2016;Joshi et al, 2016;Bedini et al, 2017;Sharopov et al, 2020). Phenylpropanoids (73.5%) constitute the main group of essential oil compounds.…”

“…In Europe the plant's uses also included constipation, intestinal cramps, ulcers and cancer (Obolskiy et al, 2011). In Arabic cultures, the species was used in the treatment of insomnia, gingivitis, foot and mouth disease and as an agent for masking the taste of medicines, while in Central Asia, including Russia, it was used to treat irritation, allergic rashes, gastritis, dyspepsia, dermatitis, and to promote digestion and improve appetite (Mamedov et al, 2004;Sharopov et al, 2020). In Azerbaijan, A. dracunculus was used as an anti-epileptic drug (Alakbarov, 2001).…”

“…, AbtahiFroushani et al (2016),Behbahani et al (2017),Osanloo et al (2017),Bussmann et al (2020),Sharopov et al (2020) Methyl eugenolAyoughi et al (2011),Obolskiy et al (2011),Obistioiu et al (2014),Tak et al (2014),Karimi et al (2015),Abdollahnejad et al (2016),Abtahi Froushani et al (2016),Behbahani et al (2017),Osanloo et al (2017),Szczepanik et al (2018), Bussmann et al (2020), Sharopov et al (2020) Elemicin Ayoughi et al (2011), Obolskiy et al (2011), Szczepanik et al (2018), Bussmann et al (2020) Isoelemycin Obolskiy et al (2011), Szczepanik et al (2018) Eugenol Ayoughi et al (2011), Osanloo et al (2017), Bussmann et al (2020) Isoeugenol methyl ether Szczepaniket al (2018), Socaciu et al (2020) Asarone, isoeugenol methyl trans-anethole Obolskiy et al (2011) (Z)-Anethole Ayoughi et al (2011), Obolskiy et al (2011), Bussmann et al (2020) Prestragol Talbi et al (2016) Anethole, carpacin Abdollahnejad et al (2016) Dillapiole Ayoughi et al (2011), Behbahani et al (2017) 3-(p-Methoxyphenyl)-1,2-propanediol Güvenalp et al (2017) Monoterpenoids Sabinene Aglarova et al (2008), Ayoughi et al (2011), Obolskiy et al (2011), Karimi et al (2015), Bedini et al (2017), Behbahani et al (2017), Osanloo et al (2017), Bussmann et al (2020), Sharopov et al (2020), Socaciu et al (2020) cis allo-Ocymen, cis allo-ocymen hydrate, trans-sabinene acetate, ethyl geranyl Obolskiy et al (2011), Bussmann et al (2020) α-Fenchene, cis-sabinene hydrate, camphor, geranyl acetate, (E)-β-ionone Sharopov et al (2020) c-Terpinene Ayoughi et al (2011), Obolskiy et al (2011), Bedini et al (2017), Osanloo et al (2017), Szczepanik et al (2018), Sharopov et al (2020), Socaciu et al (2020) α-Terpinene Ayoughi et al (2011), Obolskiy et al (2011), Bedini et al (2017), Osanloo et al (2017), Szczepanik et al (2018), Sharopov et al (2020) α-Terpineol Aglarova et al (2008), Bedini et al (2017), Szczepanik et al (2018) 4-Terpineol Obolskiy et al (2011), Szczepanik et al (2018), Sharopov et al (2020) Terpinolene Aglarova et al (2008), Ayoughi et al (2011), Obolskiy et al (2011), Karimi et al (2015), Bedini et al (2017), Szczepanik et al (2018), Bussmann et al (2020), Sharopov et al (2020), Socaciu et al (2020) α-Terpinolene Behbahani et al (2017), Osanloo et al (2017) Linalool Ayoughi et al (2011), Obolskiy et al (2011), Bedini et al (2017), Behbahani et al (2017), Osanloo et al (2017), Szczepanik et al (2018), Sharopov et al (2020) Limonene Aglarova et al (2008), Ayoughi et al (2011), Obolskiy et al (2011), Karimi et al (2015), Bedini et al (2017), Behbahani et al (2017), Osanloo et al (2017), Szczepanik et al (2018), Bussmann et al (2020), Sharopov et al (2020) allo-Ocimene Ayoughi et al (2011), Obolskiy et al (2011), Bedini et al (2017), Behbahani et al (2017) trans-allo-Ocimene Bussmann et al (2020), Sharopov et al (2020) cis-β-Ocimene Joshi et al (2016), Sharopov et al (2020), Socaciu et al (2020) trans β-Ocimene Aglarova et al (2008), Sharopov et al (2...…”

Beneficial Role of Antioxidant Secondary Metabolites from Medicinal Plants in Maintaining Oral Health

“…To cure mouth ulcers [56] [61] Estragol (methyl chavicol), (E)anethole, capillene, methyl eugenol, (E)-β-ocimene, (E)-α-ocimene, (Z)-β-ocimene limonene, α-pinene, α-terpinolene, isoelemicin, elemicin 5-phenyl-1,3pentadiyne, α-phellandrene, β-phelland-rene, pulegone, (Z)-artemidin, hinokitiol, and acenaphthene [63] In vitro(antibacterial) on Staphylococcus aureus (ATCC 23235). Concentration-10 µL of tarragon oil tested on agar plate.…”