Phytochemical Studies of Fractions and Compounds Present in Vernonanthura Patens with Antifungal Bioactivity and Potential as Antineoplastic

The temperature and extraction time of aqueous extracts of Vernonanthura patens (Kunth) H. Rob.(AEVP) leaves obtained by decoction were optimized for maximum recovery of DPPH radical scavenging activity, ABTS + inhibition activity, total phenolic content (TPC) and total flavonoids content (TFC) using response surface methodology (RSM). A central composite design (CCD) of 13 experimental runs was applied and second order polynomial models were used to describe the responses of the assessed extraction parameters. The optimized conditions: 79.79 °C and 126.23 minutes were found using the composite desirability function. The scavenging activity of assessed extracts could be correlated mostly to the presence of malic acid, succinic acid, α-ketoglutaric acid, citric acid, m-hydroxybenzoic acid, caffeic acid, inositol, and β-amyrin detected by gas chromatography-mass spectrometry (GC-MS). These results have not been reported and support the potential application of AEVP as natural source of antioxidants.

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Medicinal Plants Used by Indigenous Communities of Oaxaca, Mexico, to Treat Gastrointestinal Disorders

Pérez-Ochoa¹,

Chávez-Servia²,

Vera-Guzmán³

et al. 2019

Pharmacognosy - Medicinal Plants

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The use of medicinal plants for the treatment of gastrointestinal disorders and ethnodiseases such as diarrhea, stomachache, dysentery, "empacho" (blockage), and bile is a common strategy among indigenous communities. It is estimated that approximately 34% of medicinal plants are used to treat diseases of the digestive tract. In Mexico, gastrointestinal infections caused by bacteria, parasites, or viruses represent one of the main causes of death in children in rural populations. Our objective was to document the use of medicinal plants used by the indigenous groups of Oaxaca, Mexico, for the treatment of gastrointestinal disorders, based on previous studies, experiences, and field observations in indigenous communities and supplemented with bibliographic references. In Oaxaca, there are 16 indigenous groups, the largest being the speakers of the Zapoteco, Mixteco, Mazateco, Mixe, Chinanteco, Amuzgo, Tacuate, Chatino, and Cuicateco languages. In this review of the medicinal plants used for gastrointestinal disorders, 186 species were grouped into 147 genera and 71 botanical families, among which the largest number of species belonged to Asteraceae (29), Fabaceae (15), Euphorbiaceae (9), Solanaceae (9), and Lamiaceae (9). Different pharmacological studies showed potential for preventing microbial and fungal pathogens that cause gastrointestinal disease.

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Phytochemical Studies of Fractions and Compounds Present in Vernonanthura Patens with Antifungal Bioactivity and Potential as Antineoplastic

Cited by 3 publications

References 17 publications

Antibacterial and antibiofilm activity of extracts from sponge-associated bacterial endophytes

Antibacterial and antibiofilm activity of extracts from sponge-associated bacterial endophytes

Antioxidant activity optimization and GC-MS profile of aqueous extracts of Vernonanthura patens (Kunth) H. Rob. leaves

Medicinal Plants Used by Indigenous Communities of Oaxaca, Mexico, to Treat Gastrointestinal Disorders

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