Phytochemical screening of tanzanian medicinal plants. I

Chhabra, S. C.; Uiso, F.C.; Mshiu, E.N.

doi:10.1016/0378-8741(84)90037-0

Cited by 145 publications

(88 citation statements)

References 5 publications

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“…The chemical constituents were screened according to Chhabra [9] In this paper, the description by Huft [2] is enriched by our botanical observations. It is evident that the analyzed spice has a great coincidence by the description done by Ferrufino & Gómez-Laurito [11], and Cáceres [12].…”

Section: Phytochemical Studiesmentioning

confidence: 99%

Pharmacognostic and Phytochemical Studies of <i>Smilax domingensis</i> Willd. in Cuba

Yaque¹,

Monan²,

Cuéllar³

et al. 2017

AJPS

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A preliminary pharmacognostical and phytochemical evaluation of Smilax domingensis Willd., (Smilacaceae) was realized to determine the macromorphology and micromorphology characteristics, the physicochemical and phytochemical parameters from the rhizome of this spice that grows in Cuba. This crude drug showed the characteristic physicochemical values such as moisture content (13.11%), extractable matter in ethanol at 70% (13.53%), total ashes (3.45%), water soluble ashes (2.43%) and acid insoluble ashes (0.64%). Phytochemical screening revealed the possible presence of alkaloids, oils and/or fats, coumarins, saponins, flavonoids, pyrogallol-type tannins, quinones, catechins, reductants sugars, triterpens and steroids and absence of resins, aminoacids, cardiotonic glycosides, anthocyanidins and astringent and/or bitter principles, realized under WHO parameters.

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Section: Phytochemical Studiesmentioning

confidence: 99%

Pharmacognostic and Phytochemical Studies of <i>Smilax domingensis</i> Willd. in Cuba

Yaque¹,

Monan²,

Cuéllar³

et al. 2017

AJPS

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“…In the eastern and southern Africa regions, the plants are used to treat stomach-ache, urinal-genital problems, excessive menstruation, tuberculosis and cardiac palpitations (Melo-Reis et al, 2010). The plant Synadenium glaucescens, which belongs to this family, is widely used in Tanzania to treat various diseases including skin conditions, sores and wounds (Chhabra et al, 1984). However, unlike other family members, scientific information about the effectiveness of traditionally prepared S. glaucescens extracts against microbial agents is scanty.…”

Section: Introductionmentioning

confidence: 99%

Effect of crude root extract from Synadenium glaucescens on selected bacterial infections in albino mice (Mus musculus)

Max¹,

Mwageni²,

Bakari³

2014

J. Med. Plants Res.

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Studies were carried out to investigate the effect of root extract from a tropical plant Synadenium glaucescens against two pathogenic species of bacteria in mice. A total of 120 mice were used in two experiments involving two bacterial species, Staphylococcus aureus and Pseudomonas aeruginosa. In each experiment, 60 mice were randomly divided into 6 groups with or without bacterial infection and with or without root extract. Clinical signs and survival of the mice were monitored; skin, kidneys and livers were examined for gross lesions, histopathological changes and bacterial counts. Results indicated that mice infected with the two bacteria and treated with the root extract from S. glaucescens had significantly less (P < 0.05) severe skin lesions compared to mice from the untreated groups. Histopathological examination of liver and kidney tissues showed hydropic degeneration and inflammatory reaction in uninfected groups receiving the extracts. Protein in tubular lumens, desquamated tubular epithelium and necrosis around central veins were observed in livers of mice infected with S. aureus and treated with the extract at 50 mg/kg body weight. It is concluded that root extract from S. glaucescens had significant antibacterial activity against the tested bacteria. Histopathological changes in the kidneys and livers of mice which received the extract alone suggested that high doses of the tested extract could be harmful to the mice. Further studies are needed to find out optimum dosage and whether the extract is harmful to other organs.

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“…The species Synadenium glaucescens (Mvunjakongwa in Swahili, Liyugi in Bena language) are found growing in several regions in Tanzania and indigenous people have been using them for treatment of both animal and human illnesses. A juice made from freshly-crushed leaves is usually ingested for treatment of excessive menstruation (Chhabra, Uiso & Mshiu, 1984). A leaf decoction with lime juice, baking soda and honey added is ingested to treat asthma; the ashes of dried leaves are mixed with water and applied to the skin to treat leprosy (Schmelzer, Gurib-Fakim, Arroo, Bosch, de Ruijter, & Simmonds, 2008).…”

Section: Introductionmentioning

confidence: 99%

Optimization of Extraction Conditions and Phytochemical Screening of Root Extract of Synadenium glaucescens Pax

Mabiki

Magadula²,

Mdegela³

et al. 2013

IJC

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Optimization of extraction conditions and phytochemical screening of the root bark of Synadenium glaucescens were carried out in a stepwise manner in order to obtain the highest yields and the constituents of the extracts. Sequential extraction using Soxhlet method was performed using dichloromethane, hexane and petroleum ether, respectively, each followed by ethanol. Extraction conditions included: running time of 2 to 6 hours, temperature at 25 o C to 95 o C and particle size ranging from 0.4mm to >3mm diameter. Phytochemical screening was done using derivatisation techniques, gas chromatography-mass spectrometry and high performance liquid chromatography. Extraction with dichloromethane followed by ethanol resulted in a higher yield by 25%, within 4 hrs of extraction, particle size of 1mm, at temperatures of 30 o C for dichloromethane and 75 o C for ethanol. Fatty acid analysis indicated absence of free fatty acids in both Dichloromethane and ethanolic extracts. Silylation and Thin Layer Chromatography indicated the presence of non hindered and hindered functionality and the presence of triterpenoids in the dichloromethane extract. Phytochemical screening of the dichloromethane extracts indicated that it is composed of two main triterpenoids that best matched with Lanosterol (42%) and Cycloartenol (31%). Other minor compounds identified through chromatographic analysis were phytol, ergostadiol, hentriacontane, sitastirol aceate, lupeol and hopenone. The ethanolic extracts indicated the presence of polyphenolic compounds.

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Phytochemical screening of tanzanian medicinal plants. I

Cited by 145 publications

References 5 publications

Pharmacognostic and Phytochemical Studies of <i>Smilax domingensis</i> Willd. in Cuba

Pharmacognostic and Phytochemical Studies of <i>Smilax domingensis</i> Willd. in Cuba

Effect of crude root extract from Synadenium glaucescens on selected bacterial infections in albino mice (Mus musculus)

Optimization of Extraction Conditions and Phytochemical Screening of Root Extract of Synadenium glaucescens Pax

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Phytochemical screening of tanzanian medicinal plants. I

Cited by 145 publications

References 5 publications

Pharmacognostic and Phytochemical Studies of &lt;i&gt;Smilax domingensis&lt;/i&gt; Willd. in Cuba

Pharmacognostic and Phytochemical Studies of &lt;i&gt;Smilax domingensis&lt;/i&gt; Willd. in Cuba

Effect of crude root extract from Synadenium glaucescens on selected bacterial infections in albino mice (Mus musculus)

Optimization of Extraction Conditions and Phytochemical Screening of Root Extract of Synadenium glaucescens Pax

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Product

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Pharmacognostic and Phytochemical Studies of <i>Smilax domingensis</i> Willd. in Cuba

Pharmacognostic and Phytochemical Studies of <i>Smilax domingensis</i> Willd. in Cuba