PHYTOCHEMICAL SCREENING OF SIJUKKOT EKSTRACT (Lactuca Indica L.)

Panjaitan, Jesica C.R.; Silalahi, Albinus

doi:10.24114/ijcst.v3i2.19527

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…4,5 Hasil penelitian Panjaitan Y. dan Silalahi A. menyimpulkan bahwa ekstrak etanol daun tanaman Sijukkot mengandung konstituen fitokimia yang memungkinkan dapat digunakan dalam formulasi obat, diantaranya Flavonoid, Alkaloid, Saponin, Tanin, Steroid dan Terpenoid. 6 Daun Sijukkot (Lactuca indica L) Merupakan tanaman khas dan langka yang tumbuh dikawasan hutan Dolosanggul, Kabupaten Humbang Hasundutan, Sumatra Utara. Tanaman ini banyak dimanfaatkan masyarakat sekitar untuk pengobatan tradisional (self-medication) seperti obat deman, batuk, flu, dan sakit perut sebelum obat modern ditemukan.…”

Section: Pendahuluanunclassified

Effect of Addition of Ethanol Extract from Sijukkot Leaves (Lactuca Indica L.) on Cholesterol Reduction in Male Strain Rats (Rattus Norvegicus)

Munte

Silalahi²

2022

IJCST

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Cholesterol is one of the lipids that can form cell membranes and extremity layers and functions as a lipoprotein compound. Rising cholesterol levels can cause various diseases. The leaves of the sijukkot plant have been used as a lowering of cholesterol levels in the body. By using SPSS analysis, it was found that the Shapiro-Wilk Normality Test with a sig value > 0.05, the data were normally distributed. The results of the analysis in the Test of Homogeneity of Variances table obtained a Sig value of 0.510. Thus the value of Sig = 0.510 > 0.05, then Ho is accepted. Thus, the ethanol extract of sijukkot leaves has the potential to reduce cholesterol levels. By using four different doses, the rat group at a dose of 100 mg/kgBW showed cholesterol levels of 77.25 (mg/dL) ± 9.14, the rat group at a dose of 200 mg/kgBW showed cholesterol levels of 62.75 (mg/dL) ± 5.44, the rat group at a dose of 200 mg/kgBW showed a cholesterol level of 62.75 (mg/dL) ± 5.44. 300 mg/kgbw showed a cholesterol level of 61.50 (mg/dL) ± 4.1 and a group of rats at a dose of 400 mg/kgbw showed a cholesterol level of 54.50 (mg/dL) ± 4.1

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Section: Pendahuluanunclassified

Effect of Addition of Ethanol Extract from Sijukkot Leaves (Lactuca Indica L.) on Cholesterol Reduction in Male Strain Rats (Rattus Norvegicus)

Munte

Silalahi²

2022

IJCST

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“…Uji steroid dan terpenoid dilakukan dengan dengan 1 mL ekstrak di tambahkan dengan pereaksi Lieberman-Burchard. Positif terpenoid jika terbentuk warna merah atau kuning dan positif steroid jika terbentuknya warna hijau dan biru (Panjaitan C.R.J., 2020).…”

Section: Senyawa Steroid Dan Terpenoidunclassified

CYTOTOXIC ACTIVITY OF KASUMBA FLOWER ETHANOL EXTRACT TURATE (Carthamus tinctorius Linn.) AGAINST THE LINE OF CANCER CELLS T47D BREASTS

Malik

Malaka²,

Fristiohady³

et al. 2022

JFSP

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Breast cancer is a type of cancer with a high prevalence in the world and causes death in women. Chemotherapy is one type of treatment that is widely used. However, the problems of chemotherapy drugs such as side effects, drug resistance and inadequate efficacy. So, to overcome these problems, many natural ingredients have been explored to find anticancer agents that are expected to have good efficacy with minor side effects. Kasumba turate flowers (Carthamus tinctorius Linn.) is a plant from the Asteraceae tribe which is known to contain secondary metabolites with pharmacological activity as anticancer. This study aims to determine the types of secondary metabolites and the cytotoxic activity of the ethanolic extract of Kasumba turate flower against the T47D breast cancer cell line using the MTT assay method. Kasumba turate flower extract was obtained by maceration using 96% ethanol solvent, so that a concentrated extract with a weight of 107.8 grams was obtained with a yield value of 10.81%. The extract obtained was then subjected to a phytochemical screening test using the tube method and the results are alkaloids, flavonoids, tannins, and terpenoids. In the cytotoxic activity test, the test samples were varied into 7 concentration series, namely 10, 50, 100, 200, 400, 800 and 1000 ppm. The positive control used was 5-Fu. Cytotoxic parameter (IC50 value) was determined using GraphPad Prism and obtained IC50 5-Fu value of 65.88 ppm with active category while IC50 of the test sample was 157.3 with moderately active category as anticancer breast.

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PHYTOCHEMICAL SCREENING OF SIJUKKOT EKSTRACT (Lactuca Indica L.)

Cited by 2 publications

References 7 publications

Effect of Addition of Ethanol Extract from Sijukkot Leaves (Lactuca Indica L.) on Cholesterol Reduction in Male Strain Rats (Rattus Norvegicus)

Effect of Addition of Ethanol Extract from Sijukkot Leaves (Lactuca Indica L.) on Cholesterol Reduction in Male Strain Rats (Rattus Norvegicus)

CYTOTOXIC ACTIVITY OF KASUMBA FLOWER ETHANOL EXTRACT TURATE (Carthamus tinctorius Linn.) AGAINST THE LINE OF CANCER CELLS T47D BREASTS

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