Phytochemical screening, antimicrobial and antioxidant efficacy of different extracts of Rumex dentatus L. – A locally used medicinal herb of Kashmir Himalaya

Nisa, Humeera; Kamili, Azra N.; Bandh, Suhaib A.; Shajr-ul-Amin,; Lone, Bashir A.; Parray, Javid A.

doi:10.1016/s2222-1808(13)60097-3

Cited by 32 publications

(32 citation statements)

References 28 publications

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“…Our study is in accordance with previous studies which indicate that the antibacterial activities depend considerably on extraction method, the solvent nature and the strain tested 62,58,31 .…”

Section: Staphylococcus Aureussupporting

confidence: 93%

“…The lack of antibacterial activity in some of the concentrations of the extract is not surprising as a number of plant extracts which have been found uneffective against certain test organisms at lower concentrations and may be attributed to the presence of lesser amounts of the antimicrobial compounds 58 . But in our study, the results revealed that E.coli ATTC 25922 was resistant to all extracts used.…”

Section: Staphylococcus Aureusmentioning

confidence: 99%

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2017

IJPSR

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Aristolochia longa L. (Aristolochiacea) is a native plant of Algeria used in traditional medicine. This study was devoted to the determination of polyphenols, flavonoids, and tannins contents of A. longa L. extracts. Extracts were prepared from aerial parts (stems and leaves), fruits and tubers by using various solvents with different polarities such as acetone, methanol and distilled water. Acetone extracts from the aerial parts presented the highest contents of polyphenols (525.43±29.6 µg/mg) followed by fruit aqueous extract (518.54±14.93 µg/mg), while the aerial parts methanol extract shown the highest flavonoid content (52.37±0.94 µg/mg) and exhibited the highest antioxidant capacity of DPPH and reducing power (55.04 ±1.29 µg/mL and 0.2±0.019 mg/mL, respectively), therefore the aerial parts acetone extract showed the highest antioxidant capacity in the β-carotene bleaching inhibition test with 57%. For antimicrobial activity, the fruit methanol extract was too efficient against the bacterial strains tested, whereas no effect was observed when these extracts were tested against fungi. The protein denaturation was found in the aerial parts acetone extract to be 78.35±6.18% followed by fruit methanol extract, 68.04±4.72% at the dose 500 µg/mL, with regards to standards diclofenac sodium. These preliminary results could be used to justify the traditional use of this plant and its bioactive substances could be exploited for therapeutic purposes.

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Section: Staphylococcus Aureussupporting

confidence: 93%

Section: Staphylococcus Aureusmentioning

confidence: 99%

Untitled

2017

IJPSR

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“…This is probably why aqueous extracts lack antibacterial effects because they have concentrations of phenolic compounds dissolved in water. This is in agreement with studies conducted by Nisa and Yildirim [5,19]. The differences in the mentioned results are due to the different plant species used in the first place and to differences in the tested parts of the plants, in the tested bacterial strains and/or in the habitats of the plants in the second place.…”

supporting

confidence: 91%

Anti-Quorum Sensing and Antibacterial Activity of Rumex alveolatus

Korkorian

Mohammadi-Sichani

2017

Zahedan J Res Med Sci

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“…It has been well documented that the extraction of saffron was carried out in methanol as documented in previous literature on saffron as well as on other plant materials (Parray et al 2010;Nisa et al 2013). In our study, both the plant extracts showed varying degrees of inhibitory effects on the pathogenic bacterial strains.…”

Section: Antibacterial Activitymentioning

confidence: 97%

Antibacterial and antioxidant activity of methanol extracts ofCrocus sativusL.c.v. Kashmirianus

Parray

Kamili

Hamid

et al. 2014

Frontiers in Life Science

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In this study, we investigated the antibacterial and antioxidant activities of Crocus sativus L. Kashmirianus c.v. extracts (callus and stigmas). Profuse callus was obtained on MS medium enriched with BAP (20 µM) + NAA(15 µM) under in vitro conditions from corm slices. Four pathogenic bacterial strains (Staphylococcus aureus CD0001, Escherichia coli CD0006, Pseudomonas aeruginosa CD0023 and Shigella flexneri CD0033) were used for determining the antibacterial activity of extracts. The antioxidant activity was determined by DPPH assay, DNA protection assay, FTC method, TBA assay and lipid peroxidation assay. The methanol stigma extract of saffron was found to be more effective in inhibiting all the pathogenic strains. The stigma extract also showed significant radical scavenging or chelation capacities in four of the methods; however, callus extract exhibited maximum inhibition of peroxy-radicals in lipid peroxidation assay. The protocol for callus production is described. It was concluded that as well as the specific parts of plants displaying diverse pharmacological activities, callus produced under in vitro conditions will assist in enhancing the production of secondary metabolites, which will reduce the pressure on natural saffron.Keywords: antioxidant activity; callus; in vitro culture; MIC; methanol; saffron; stigma Abbreviations: BAP = 6-benzyl adenine purine BHT = butylated hydroxyl toluene FTC = ferric thiocyanate MIC = minimum inhibitory concentration NAA = naphthalene acetic acid TBA = thiobarbituric acid.

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Phytochemical screening, antimicrobial and antioxidant efficacy of different extracts of Rumex dentatus L. – A locally used medicinal herb of Kashmir Himalaya

Cited by 32 publications

References 28 publications

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Anti-Quorum Sensing and Antibacterial Activity of Rumex alveolatus

Antibacterial and antioxidant activity of methanol extracts ofCrocus sativusL.c.v. Kashmirianus

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