Phytochemical screening and pharmacological evaluations for the antifertility effect of the methanolic root extract of Rumex steudelii

Antifertility activity of the methanolic leaf extract of Cissampelos pareira in female albino mice

“…The present study is comparable with the studies made by Makonnen et al (1999) and Gebrie et al (2005) who had reported antifertility effect with similar observations in guinea pigs and rats on treatment with seed extract of Ricinus communis and root extract of Rumex steudelii, respectively. However, significant decrease in the duration of proestrus and metestrus stage in experimental group was recorded than those of control animals.…”

Potential genotoxicity of plant extracts used in Ethiopian traditional medicine

“…The cover pods of G. lotoides were separated from the dried fruits, and after drying the seeds they were macerated for 72 h with 60% methanol (Demma et al, 2007). Dried and powdered roots of P. zeylanica and R. steudelii, and dried leaves of T. schimperi were macerated in 80% methanol for three consecutive days as described elsewhere (Dagne et al, 1998;Gebrie et al, 2005b;Gebre-Mariam et al, 2006). The metanolic extracts of all plants were then vacuum filtered and dried in hot oven at 25-30 • C.…”

Biologically active substances-enriched diet regulates gonadotrope cell activation pathway in liver of adult and old rats

“…Chen et al (2010) indicate that genistein and resveratrol can increase the ovarian follicular reserve and prolong the ovarian lifespan in rats. Gebrie et al (2005) proved that the extract of Rumex steudelii (Ethiopian plant which roots contain phytosterols and polyphenols) prolonged significantly the oestrus cycle and the dioestrous phase. Studies of Colitti et al (2007) revealed that polyphenols can protect from stress which activates the hypothalamo–pituitary–adrenal axis leading to enhanced glucocorticoid secretion and concurrently disrupts ovarian cycle.…”