Antifertility activity of the methanolic leaf extract of Cissampelos pareira in female albino mice

Ganguly, Mausumi; Borthakur, Mridul Kr.; Devi, Nirada; Mahanta, Rita

doi:10.1016/j.jep.2007.01.023

Cited by 55 publications

(39 citation statements)

References 7 publications

(8 reference statements)

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“…The findings of the present study were agreed with previous studies which reported the effect of Inula viscose and Bambusa vulgaris leaf extract on implantation and abortion in rats and rabbits (Yakubu and Bukoye, 2009). In this study, an increase in prolactin level was observed (Table 5); these findings were also supported by Ganguly et al (2007), who reported that a combination of enhanced prolactin and suppressed LH secretion is due to prolongation of estrus cycle (Ganguly et al, 2007). An imbalance in endogenous estrogen and progesterone levels could be responsible for anti-implantation activity (Dhanwad et al, 2005).…”

Section: Hormonal Analysissupporting

confidence: 82%

“…The reduction in the concentration of FSH is an indication of disturbance of estrus cycle and ovulation (Ganguly et al, 2007). LH is required for continued development and normal function of corpora lutea.…”

Section: Hormonal Analysismentioning

confidence: 99%

“…Bark of F. racemosa showed a wide range of pharmacological actions hypoglycemic, hyperlipidemia, renal anticarcinogenic, antidiuretic, antitussive, hepatoprotective, radioprotective, antiulcer, anti-inflammatory, antidiarrheal and antifungal, β-sitosterol, glauanol acetate, the active constituent [2]. However, scientific study of this plant in relation with the potentiality as an effective antifertility agent is still fragmentary.…”

Section: Introductionmentioning

confidence: 99%

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Evaluate the Antifertility Potential of Ficus Racemosa Linn Bark in Female Wistar Rats

Shah¹

2016

Asian J Pharm Clin Res

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Objective: The present study was formulated to evaluate the antifertility potential of Ficus racemosa Linn bark on female Wistar rats.Methods: Effects of F. racemosa bark extract were studied on physicochemical parameters, successive solvent extraction, and phytochemical screening and antifertility activity. After acute oral toxicity study, antifertility activity in proven fertile female Wistar rats at the doses 500 mg/kg b.wt./day for 30 days. Effects on dimensions of the reproductive outcome, anti-implantation, abortifacient, estrogenic, and antiestrogenic activity were observed.Results: Phytochemical studies of F. racemosa bark shown a positive test for alkaloids, steroid, flavonoids, terpene, carbohydrates, and tannin. The extract of F. racemosa has the antifertility effect; the control rats showed a good number of litters. Treatment of animal with different extracts resulted a significant (p<0.05, p<0.01). Antifertility activity of 56.5% and 40.3% was exhibited by alcoholic F. racemosa extract (AFR) and aqueous F. racemosa Extract (WFR), respectively. After 21 days of the extract-free period, the antifertility effect of the extracts was reversed. The extract treatment with AFR, an increase in the percentage of resorption index indicates the failure in development of embryo. The mean percentage of anti-implantation and percent resorption (abortifacient) was found to be highest for AFR-41.21%, WFR 28.07, and AFR-32.56%, WFR-20.76%, respectively. The decrement in implantation caused by the extracts may be due to estrogenic or antiestrogenic activity. However, along with standard, AFR exhibiting more potent estrogenic and less potent antiestrogenic when compared with standard. Conclusion:The above results revealed the potential, reversible female antifertility effect of alcoholic extract F. racemosa bark.

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Section: Hormonal Analysissupporting

confidence: 82%

Section: Hormonal Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Evaluate the Antifertility Potential of Ficus Racemosa Linn Bark in Female Wistar Rats

Shah¹

2016

Asian J Pharm Clin Res

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“…Anti-diarrhoeal activity [86] , Gastroprotective activity [87] , Chemo-preventive effects [88] , Anti-hyperglycemic activity [89] , Antioxidant and immunomodulatory activity [90] , Anti-inflammatory activity [91,92] Anti-fertility activity [93,94] , Memory enhancing activity [95] , Anti-nociceptive and Antiarthriritic activity [96] , Cardioprotective activity [97] , Anti-oxidant activity [98] Anti-haemorrhagic effects [99] , Hepato-protective activity [100] 3.…”

Section: Diuretic Activitymentioning

confidence: 99%

A Review on Medicinal Plants Used as Diuretics From Karnataka State

Paarakh¹

2017

WJPPS

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Medicinal herbs are the significant source for treatment of number of diseases, one such is Diuretics. Mono and poly-herbal preparations have been used as diuretics. According to estimate, more than 650 mono and poly-herbal preparations in the form of decoction, tincture, tablets and capsules are from more than 75 plants that are in clinical use. There exist a large number of studies which supports the diuretic effects of traditional herbal medicines. Herbal medicine have been the most commonly prescribed medications for diuretics. They inhibit electrolyte reabsorption from the lumen of the nephron, increasing osmolarity, enhancing water and electrolyte excretion. It is important to note that there is a delicate balance between dietary sodium intake and sodium loss. If the balance is compromised and there is a greater intake of sodium into the body, but not enough sodium removal, complications of fluid overload occur, such as oedema, pulmonary oedema or high blood pressure. When there is greater removal of sodium, but not enough sodium intake, complications of fluid depletion take place, such as renal failure or reduced output of blood from the heart. The ability to induce a negative fluid balance has made diuretics useful in the treatment of a variety of conditions, particularly in hypertension and oedematous states. This review gives information about few herbal plants which are used traditionally in Karnataka as diuretics. There are a large number of studies which supports the diuretic effects of traditional herbal medicines which is presented along with chemical constituents and other pharmacological action of the plants.

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“…The roots are used for the treatment of indigestion, constipation, cough and cold and applied locally in snake bite [1]. Previous studies have reported antiviral [2], antiprotozoal [3] and antifertility [4] activities of the extracts of aerial parts of C. pareira. Regarding chemical constituents, alkaloids are reported as major constituents in leaves [5] and roots [6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Amentoflavone and Kaempferol Glycosides from the Aerial Parts of Cissampelos pareira

Devkota¹,

Miyazaki²,

Yahara³

2017

Nepal J Biotechnol

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Aerial parts of Cissampelos pareira L. (Family: Menispermaceae), commonly known as "Batulpate" in Nepal, are used for the treatment of fever, indigestion and to stop bleeding after child birth. In this study, a biflavonoid, amentoflavone; and two kaempferol glycosides, kaempferol 3-O--D-glucopyranoside and kaempferol 3-O--D-glucuronopyranoside were isolated from 70% MeOH extract of the aerial parts. Structures of these compounds were elucidated on the basis of 1 H-and 13 C-NMR spectral data. To the best of our knowledge, it is the first report on the isolation of these compounds from a plant belonging to family Menispermaceae.

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Antifertility activity of the methanolic leaf extract of Cissampelos pareira in female albino mice

Cited by 55 publications

References 7 publications

Evaluate the Antifertility Potential of Ficus Racemosa Linn Bark in Female Wistar Rats

Evaluate the Antifertility Potential of Ficus Racemosa Linn Bark in Female Wistar Rats

A Review on Medicinal Plants Used as Diuretics From Karnataka State

Amentoflavone and Kaempferol Glycosides from the Aerial Parts of Cissampelos pareira

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