Phytochemical Screening and Biological Activities of Diospyros villosa (L.) De Winter Leaf and Stem-Bark Extracts

Adu, Oluwatosin Temilade; Naidoo, Yougasphree; Lin, Johnson; Adu, Temitope Samson; Venkataramegowda, Sivaram; Dewir, Yaser Hassan; El-Banna, Antar

doi:10.3390/horticulturae8100945

Cited by 4 publications

(1 citation statement)

References 42 publications

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“…Additionally, young stem hexane extracts of R. pyrifolius contain n-hexadecanoic acid compounds in small amounts of 6.54%. This result contrasts with Adu et al (2022), who reported that n-hexadecanoic acid (11.77%) was found in the hexane leaf extract and stem extract of Diospyros villosa in high proportions.…”

Section: Gc/ms Analysis Of the Plant Extractcontrasting

confidence: 84%

Metabolite profiling of wild underutilized raspberry (Rubus pyrifolius)

ISMAINI,

SURYA

2023

Not Sci Biol

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Rubus pyrifolius J.E. Smith, one of the Rubus species, has been found in Indonesia and collected in the Cibodas Botanical Garden. Rubus species are known for their diverse triterpenes, each with unique biological functions. This research aimed to analyse the metabolite profiles of R. pyrifolius using n-hexane and methanol solvents. GC-MS analysis was used to identify volatile and semi-volatile compounds in the R. pyrifolius extracts, with compound identification based on NIST 17 through GC/MS mass spectra analysis. The results showed that the total number of identified phytochemical compounds in methanol and n-hexane extracts of R. pyrifolius were 115 and 174, respectively. Methanol extracts from R. pyrifolius flower, young leaf, mature leaf, and young stem exhibited 46, 20, 15, and 34 compounds, respectively. In contrast, n-hexane extracts from R. pyrifolius flower, young leaf, mature leaf, and young stem contained 35, 47, 29, and 63 compounds, respectively. These compounds were classified into seven phytochemical groups: alkanes, alkenes, cyclic ethers, diterpenes, fatty acids, triterpenes, and vitamin E. Furthermore, only carboxylic esters, ergosterols, esters, fatty alcohols, and phenols were found in n-hexane extracts. The methanol extract showed seven significant phytochemical groups, including linolenic acid, phthalate esters, phytol, phytosterol, sterol lipids, terpenoids, and triterpenoids. R. pyrifolius possesses a variety of bioactive phytochemical profiles that are relevant in the field of phytopharmaceuticals. Nevertheless, further research is essential to determine their biological activity.

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Section: Gc/ms Analysis Of the Plant Extractcontrasting

confidence: 84%

Metabolite profiling of wild underutilized raspberry (Rubus pyrifolius)

ISMAINI,

SURYA

2023

Not Sci Biol

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Phytochemical Assessment and Evaluation of the Anti-Oxidant, Anti-Microbial, Anti-Cholesterol, and Anti-Diabetic Activities of Triumphetta Pentandra Methanol Based Green Leaf Extract

Mwalimu,

Packirisamy

2023

J Inorg Organomet Polym

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Synergistic effect of Salvadora persica and chitosan nanoparticles against oropharyngeal microorganisms

Balto,

Bekhit,

Auda

et al. 2024

Sci Rep

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Herbal medicine combined with nanoparticles has caught much interest in clinical dental practice, yet the incorporation of chitosan with Salvadora persica (S. persica) extract as an oral care product has not been explored. The aim of this study was to evaluate the combined effectiveness of Salvadora persica(S. persica) and Chitosan nanoparticles (ChNPs) against oropharyngeal microorganisms. Agar well diffusion, minimum inhibitory concentration, and minimal lethal concentration assays were used to assess the antimicrobial activity of different concentrations of ethanolic extracts of S. persica and ChNPs against selected fungal strains, Gram-positive, and Gram-negative bacteria. A mixture of 10% S. persica and 0.5% ChNPs was prepared (SChNPs) and its synergistic effect against the tested microbes was evaluated. Furthermore, the strain that was considered most sensitive was subjected to a 24-h treatment with SChNPs mixture; and examined using SEM, FT-IR and GC–MS analysis. S. persica extract and ChNPs exhibited concentration-dependent antimicrobial activities against all tested strains. S. persica extract and ChNPs at 10% were most effective against S. pneumoni, K. pneumoni, and C. albicans. SEM images confirmed the synergistic effect of the SChNPs mixture, revealing S. pneumonia cells with increased irregularity and higher cell lysis compared to the individual solutions. GC–MS and FT-IR analysis of SChNPs showed many active antimicrobial phytocompounds and some additional peaks, respectively. The synergy of the mixture of SChNPs in the form of mouth-rinsing solutions can be a promising approach for the control of oropharyngeal microbes that are implicated in viral secondary bacterial infections.

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Phytochemical Screening and Biological Activities of Diospyros villosa (L.) De Winter Leaf and Stem-Bark Extracts

Cited by 4 publications

References 42 publications

Metabolite profiling of wild underutilized raspberry (Rubus pyrifolius)

Metabolite profiling of wild underutilized raspberry (Rubus pyrifolius)

Phytochemical Assessment and Evaluation of the Anti-Oxidant, Anti-Microbial, Anti-Cholesterol, and Anti-Diabetic Activities of Triumphetta Pentandra Methanol Based Green Leaf Extract

Synergistic effect of Salvadora persica and chitosan nanoparticles against oropharyngeal microorganisms

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