Phytochemical screening and antimicrobial activity of wild and tissue cultured plant extracts of Tylophora indica

Vanitha, A.; Vijayakumar, S.; Ranjitha, V. H; Kalimuthu, K.

doi:10.31024/ajpp.2019.5.1.3

Cited by 7 publications

(3 citation statements)

References 7 publications

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“…For instance, when under both pathogenic and abiotic stress, younger leaves prioritize pathogenic defenses, while abiotic stress tolerance is re-allocated to older leaves [20]. Other studies like those performed by Vanitha et al, conversely showed no discernable differences between wild type and tissue cultured plant extracts of Tylophora indica suggesting that variations in chemical composition must be accessed on a species basis [9].…”

Section: Three Key Considerations Regarding Methods In the Search Formentioning

confidence: 94%

“…It is postulated that these compounds are selected for over time to fortify opportunistic vulnerabilities to various abiotic threats such as nutrient deficiency, drought, lack of oxygen, excessive temperature, ultraviolet radiation, or pollution, and as a co-evolutionary biodefense to biotic agents, which include vertebrates, insects, protists, fungi, and bacteria [5][6][7][8]. A causal relationship between microbial trespass and phytochemical synthesis is supported by the discovered synthesis of some of these compounds post-infection [9,10]. Further, it is known that plant tissues often possess secondary metabolites, which are produced and used by these plants for antibacterial purposes [4].…”

Section: Antibacterial Resistance and The Need For Novel Antibiotic Cmentioning

confidence: 99%

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Challenges and Considerations in the Preparation of Novel Antibiotic Phytochemicals

Eichelbaum

Abood

Acuña

et al. 2020

EJMP

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Drug-resistant pathogenic and opportunistic bacteria pose a global health threat. Plants, particularly those employed in traditional (folk) medicine, may provide a source of antimicrobials compounds possessing novel mechanisms of action with which to combat current and emerging infectious diseases. However, experimental designs in ethnobotanical investigations of this type are complicated by several factors. Among these are chemotype variations among plants and plant parts, and potential antagonistic, additive or synergistic effects between plant compounds. These efforts are further hindered by a lack of standardized applicable chemical extraction methods in the field, which makes assessment and comparison of experimental results difficult. This overview thus seeks to provide insight into these complicating factors, give a brief historical survey of ancient investigations into antibiotics, and identify some of the strengths and weaknesses of the various modern methods and techniques routinely employed in ethnobotanical antibiotic research.

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Section: Three Key Considerations Regarding Methods In the Search Formentioning

confidence: 94%

Section: Antibacterial Resistance and The Need For Novel Antibiotic Cmentioning

confidence: 99%

Challenges and Considerations in the Preparation of Novel Antibiotic Phytochemicals

Eichelbaum

Abood

Acuña

et al. 2020

EJMP

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“…Fruit and vegetables are good sources of functional foods because they contain a lot of phytochemicals, which have a lot of health benefits [19,36,[106][107][108][109][110][111][112][113][114][115][116][117]. T. occidentalis and its various parts have been shown to have therapeutic and exploratory effects against a variety of diseases such as diabetes, cancer, malaria, and anemia [118,119]. The presence of phytochemicals makes it a good medicinal agent.…”

Section: T Occidentalis As Nutraceuticalmentioning

confidence: 99%

Food Applications of Telfairia occidentalis as a Functional Ingredient and Nanoencapsulation as a Promising Approach toward Enhancing Food Fortification

Idris Ali,

Abba Dandago,

Idris Ali

2024

Phytochemicals in Agriculture and Food

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The cucurbitaceous vegetable Telfairia occidentalis Hook. f. “Fluted pumpkin” is grown in West Africa, especially in Nigeria for its nutritious leaves and seeds. It has various industrial applications, such as food and medicine. T. occidentalis contains essential nutrients that could play a significant role in human nutrition. Based on its chemical composition and nutritional properties, it can be used to overcome malnutrition. T. occidentalis leaves and seeds are rich in phenolic compounds, minerals, vitamins, proteins, essential amino acids, and other essential phytochemicals which can play a regulatory and functional role. The leaves and seeds of this plant have also been used in different food applications. This chapter highlights the reported knowledge relevant to the use of T. occidentalis as a food fortificant and therapeutic agent based on its prominent biological activities and the presence of phytochemicals. However, conventional food fortification methods do not completely meet the functional requirements for bioactive compounds. They also have unsatisfactory flavor profiles, as well as poor stability and bioavailability. These disadvantages can be mitigated by encapsulating the bioactive components in nanoparticle-based delivery systems. Nanofood fortification has a wide range of advantages in the protection of phytochemicals through the use of an encapsulation technique, and some micronutrients that are rapidly degraded or not properly absorbed by the body can also be aided by food fortification on the nanoscale. Nanosuspensions, nanoemulsions, nanoliposomes, and cyclodextrin carriers are some of the various nanotechnology techniques that can be used for food fortification, which have been discussed in this chapter.

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Alkaloid-rich plant Tylophora indica; current trends in isolation strategies, chemical profiling and medicinal applications

Nazar¹,

Hussain²,

Khan³

et al. 2020

Arabian Journal of Chemistry

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Phytochemical screening and antimicrobial activity of wild and tissue cultured plant extracts of Tylophora indica

Cited by 7 publications

References 7 publications

Challenges and Considerations in the Preparation of Novel Antibiotic Phytochemicals

Challenges and Considerations in the Preparation of Novel Antibiotic Phytochemicals

Food Applications of Telfairia occidentalis as a Functional Ingredient and Nanoencapsulation as a Promising Approach toward Enhancing Food Fortification

Alkaloid-rich plant Tylophora indica; current trends in isolation strategies, chemical profiling and medicinal applications

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