Phytochemical Constituents from Salsola tetrandra

Abstract

The new norisoprenoid 3beta-hydroxy-5alpha,6alpha-epoxy-beta-ionone-2alpha-O-beta-d-glucopyranoside (1) and the long-chain hydroxy fatty acids 9,12,13-trihydroxyoctadeca-10(E),15(Z)-dienoic acid (2) and 9,12,13-trihydroxyoctadeca-10(E)-dienoic acid (3) were isolated from Salsola tetrandra aerial parts, together with 3,4,5-trimethoxyphenyl-beta-d-glucopyranoside (4), 9-hydroxylinaloyl glucoside (5), taxiphyllin (6), trans-N-feruloyltyramine (7), and S-(-)-trans-N-feruloyloctopamine (8). Their structures were elucidated by extensive spectroscopic analysis and chemical methods. Compounds 6 and 8 displayed mild antibacterial activity against Staphylococcus aureus, whereas compound 6 showed the highest activity in the Artemia salina bioassay.

N-trans-Feruloyltyramine as a Melanin Biosynthesis Inhibitor

“…FA, one of the phenylpropanoids, 11) was previously isolated from Annona glabra, 12) Annona cherimola, 13) Cananga odorata, 14) Polyalthia suberosa, 15) Porcelia macrocarpa (Annonaceae), 16) Salsola tetrandra, 17) Spinacia oleracea (Chenopodiaceae), 18) Piper caninum (Piperaceae), 19) and Hypecoum sp. (Papaveraceae).…”

Two New Bioactive Biphenylpropanoids from the Roots of Salsola imbricata (Chenopodiaceae) Growing in Saudi Arabia

“…Infra-red spectra were measured on a Perkin-Elmer 157G. 1 H, 13 C and 2D NMR spectra of isolated 1 and 2 were obtained in CD 3 OD on Bruker 300 MHz, 75 MHz( spectrometer using internal reference the residual solvent resonance. Coupling constants were measured in Hertz and chemical shifts were reported in ppm.…”

“…The full analysis of the 1 H and 13 C NMR spectra were obtained by using 2D NMR. The correlations observed in the (Fig.…”

“…Furthermore, antioxidant triterpenes were isolated from S. baryosma and S. somalensis 10 and new antioxidant bibenzyl derivative and isoflavonoid were isolated from S. tetrandra 11 . Our previous work on the genus led to salsolanol and biphenylsalsinol isolation from S. villosa 12 and cleomiscosin D, norisoprenoid, long-chain hydroxyl fatty acids, taxiphyllin, trans-Nferuloyltyramine S-(-)-trans-N-feruloyloctopamine and coumarinolignan from S. tetrandra 13,14 . Recent research on Salsola imbricata showed the presence of triterpene saponins from the methanolic extract of roots 14 and new isorhamnetin derivatives from the leaves 15 .…”

Cytotoxic Cardenolides from the Leaves of Calotropis gigantea

“…In continuation to our recent study on the bioactive compounds from Calotropis gigantea, 1) we herein report the isolation of two 15b-hydroxycardenolides (1, 2), 16a-hydroxycardenolide (3) along with eleven known compounds including 16a-hydroxycalotropagenin (4), 2) calactinic acid (5), [3][4][5] 12b-hydroxycoroglaucigenin (6), 6) calotropagenin (7), 7) calotoxin (8), 7) coroglaucigenin (11), 6) 16a-hydroxycalotropin (12), 2) frugoside (9), 8) 6Ј-O-(E-4-hydroxycinnamoyl)desglucouzarin (10), 9) 9,12,13-trihydroxyoctadeca-10(E),15(Z)-dienoic acid, 10) and R-(Ϫ)-mevalonolactone, 11,12) from the polar fraction of the CH 2 Cl 2 extract, and n-BuOH extract of the leaves of this plant. Structural identification was established by spectroscopic methods.…”