Phytochemical Composition, Antioxidant Activity, and the Effect of the Aqueous Extract of Coffee (<i>Coffea arabica</i> L.) Bean Residual Press Cake on the Skin Wound Healing

Affonso, Regina; Voytena, Ana Paula Lorenzen; Fanan, Simone; Pitz, Heloísa da Silva; Coelho, Daniela; Horstmann, Ana Luiza; Pereira, Alice Theresinha Cybis; Uarrota, Virgílio Gavicho; Hillmann, Maria C. R.; Varela, Lucas Andre Calbusch; Ribeiro‐do‐Valle, Rosa Maria; Maraschin, Marcelo

doi:10.1155/2016/1923754

Cited by 66 publications

(46 citation statements)

References 56 publications

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“…Thus, phenolic extracts can be obtained from coffee waste using an environmentally friendly and simple solvent extraction procedure, as well as it was reported by Affonso et al . (), who obtained higher phenolic concentration for GCC aqueous extract (3539 mg GAE/100 g), which was slightly higher than the result found in this study when ethanol was used as an ecofriendly solvent. Furthermore, the matrices analysed in this study are richer phenolic compounds resources than the other by‐products that have been studied, as aforementioned.…”

Section: Resultscontrasting

confidence: 83%

“…Depending on the existence of appropriate technology this waste can be transformed into added value products (EU and CORDIS, ). Specifically, in the coffee industry, many technologies are being approached, such as the solvent extraction (Al‐Hamamre et al ., ; Efthymiopoulos et al ., ; Loyao et al ., ) combined with ultrasound to obtain oil (Abdullah & Bulent Koc, ) and phenolic compounds (Al‐Dhabi et al ., ), aqueous solid‐liquid extraction to obtain phenolic compounds (Affonso et al ., ), pressurised‐fluid extraction of cafestol and kahweol (Belandria et al ., ), and enzymatic extraction (Ravindran et al ., ). One of the coffee industry by‐products is the cake or meal.…”

Section: Introductionmentioning

confidence: 99%

“…Relatively few studies have investigated green coffee beans waste generated by conventional pressing of green coffee beans by the coffee oil industry. It is of common knowledge that green coffee beans are a great source of bioactive compounds, such as antioxidants that work against free radicals in the human organism (Affonso et al ., ); however, there are scarce studies evaluating the potential of its press cake also as a source of these compounds, which are of special interest to the food and pharmaceutic industries nowadays. Any molecule capable of remaining with one or more unpaired electrons in its last electron layer is called free radical, which is highly unstable and reactive (Phaniendra et al ., ).…”

Section: Introductionmentioning

confidence: 99%

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An investigation into green coffee press cake as a renewable source of bioactive compounds

Oliveira

Silva

Santos

et al. 2019

Int J of Food Sci Tech

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The residual biomass of coffee, obtained after the oil extraction from coffee beans, called coffee beans residual press cake, has been attracted interest as a source of compounds with antioxidant capacity. This study investigated the effects of ethanolic and methanol-acetone extracts of green coffee beans (GCB) and its residual press cake (GCC) on the phenolic composition and antioxidant capacity. Antioxidant capacity was assayed through five different methods (total phenolic compounds, •DPPH, ABTS, FRAP and b-carotene bleaching assay), and the phenolic profile of the samples through High Performance Liquid Cromatography. GCB and GCC enclosed chlorogenic (55.16 and 64.96 mg g À1 , respectively) and caffeic (25.07 and 44.37 mg g À1 , respectively) acids as the major components, and the cake presented higher antioxidant capacity than the actual green bean. Antioxidant capacity was higher for GCC extracted with methanol and acetone. This study on the evaluation of the effects of the type of solvent on the bioactive compounds from GCB and GCC showed that this by-product can be a source of new value-added products, such as phenolic antioxidant adjuncts for food or pharmaceutic processing.

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Section: Resultscontrasting

confidence: 83%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An investigation into green coffee press cake as a renewable source of bioactive compounds

Oliveira

Silva

Santos

et al. 2019

Int J of Food Sci Tech

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“…Coffee beans residual press cake is obtained after the cold press method of extracting the oil fraction. The resultant biomass is claimed to be rich in bioactive compounds of interest for human health and cosmetics, with phenolic content ranging from 24.13 ± 1.45 to 35.39 ± 3.69 mg gallic acid equivalent/g biomass, to green and roasted residual press cake, respectively [14].…”

Section: Present Studymentioning

confidence: 99%

Phytochemical Profile and in vitro Assessment of the Cytotoxicity of Green and Roasted Coffee Oils (Coffea arabica L.) and their Polar Fractions

Lorenzen¹,

Affonso²,

Pitz³

et al. 2018

Rec.Nat.Prod.

Self Cite

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Green Coffea arabica L. seed oil (GCO) has been used as an active cosmetic ingredient in many skin care products, due to its composition and balance of fatty acids. On the other hand, while roasted coffee oil (RCO) is mainly used for imparting aroma in the food industry, there is no data available to suggest its safety in cell-based model systems. In this context, the present study aims to evaluate the chemical composition of GCO, RCO, and their correspondent polar fractions (PFs); and assess their cytotoxicity and antioxidant potential in vitro. RCO and RCO PF exhibited significantly higher amounts of phenolic compounds, when compared to both GCO and GCO PF. In the DPPH assay, after 5 min of incubation, RCO inhibited about 80% of radicals, while GCO only achieved half of this activity. Similar results were also obtained for their PFs. Upon exposure to GCO, no cytotoxic effects were observed, in fact, there were slight increments in cell proliferation. Nevertheless, cell exposure to RCO led to significant decreases in cell viability. Increases in the concentration of coffee oil PFs were associated with correspondent relevant increased cytotoxicity. Upon hydrogen peroxide-induced oxidative stress, neither GCO nor RCO treatment were effective in protecting cells.

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“…Arabica coffee extract, which is administered on hairless mice, can increase collagen level and reduce epidermal hyperplasia because its polyphenol has anti-oxidant and anti-inflammation profile (Po-Yuan et al, 2017). Coffee extract can repair skin wounds on rats (Affonso et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

POTENTIAL OF ACEH ARABICA COFFEE EXTRACT (Coffea arabica L.) IN REJUVENATION OF AGING SKIN IN RAT

Safrida

Sabri

2017

J Kedokt Hewan

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This study aimed to determine the potency of Aceh Arabica coffee in rejuvenation of aging skin in rat. This study was conducted in vivo using completely randomized design (RAL), which consisted of 4 treatment groups as follows: premenopausal rats as negative control (KON), premenopausal rats with administration of distilled water as placebo (PLS), premenopausal rats with administration of ethinylestradiol 9x10 -3 mg/day/200 g BW (EST), and premenopausal rats with coffee extract administration of 300 mg/day/200 g BW (KOP). Each treatment group consisted of 5 rats. The parameters observed were skin collagen, water content/skin hydration, and skin ribonucleic acid (RNA) level. The data were analyzed using analysis of variance (ANOVA) and Duncan test using SAS 9.13 software. The result showed the average skin collagen and RNA levels were higher in premenopausal rats with administration of coffee extract and ethinylestradiol (P<0.05) than control rats. On the other hand, average of water level in premenopausal rats with coffee extract and ethinylestradiol administration were the same as control rats. It can be concluded that administration of Aceh Arabica coffee extract can repair skin quality, which is indicated by the increase of collagen and RNA level on aging skin in rat. ____________________________________________________________________________________________________________________ ABSTRAKPenelitian ini bertujuan mengetahui potensi ekstrak kopi Arabika Aceh untuk meningkatkan kualitas kulit pada tikus yang mengalami penuaan. Untuk mencapai tujuan tersebut dilakukan penelitian secara in vivo dengan menggunakan rancangan acak lengkap (RAL), yang terdiri atas empat perlakuan masing-masing terdiri atas lima ekor tikus, yaitu KON= tikus premenopause sebagai kontrol negatif, PLS= tikus premenopause yang dicekok akuades sebagai plasebo, EST= tikus premenopause yang diberi etinilestradiol sebanyak 9x10 -3 mg/hari /200 g BB, KOP = tikus premenopause yang diberi ekstrak kopi 300 mg/hari/200 g bobot badan. Parameter yang diamati ialah kadar kolagen kulit, kadar air kulit, dan kadar ribonucleic acid (RNA) kulit. Data yang diperoleh dianalisis dengan menggunakan analysis of variance (ANOVA) dan dilanjutkan dengan uji Duncan dengan menggunakan program software SAS 9.13. Hasil penelitian menunjukkan bahwa rataan kadar kolagen kulit dan kadar RNA kulit pada tikus premenopause yang diberi ekstrak kopi dan etinilestradiol lebih tinggi (P<0,05), bila dibandingkan dengan tikus kontrol. Sebaliknya, rataan kadar air kulit pada tikus premenopause yang diberi ekstrak kopi dan etinilestradiol, sama dengan tikus kontrol. Dapat disimpulkan bahwa pemberian ekstrak kopi Arabika Aceh dapat memperbaiki kualitas kulit yang ditandai dengan terjadinya peningkatan kadar kolagen dan kadar RNA kulit pada tikus yang mengalami penuaan ____________________________________________________________________________________________________________________ Kata kunci: kopi Arabika (Coffea arabica L.), kolagen, ekstrak, tikus, RNA, kualitas kulit

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Phytochemical Composition, Antioxidant Activity, and the Effect of the Aqueous Extract of Coffee (Coffea arabica L.) Bean Residual Press Cake on the Skin Wound Healing

Cited by 66 publications

References 56 publications

An investigation into green coffee press cake as a renewable source of bioactive compounds

An investigation into green coffee press cake as a renewable source of bioactive compounds

Phytochemical Profile and in vitro Assessment of the Cytotoxicity of Green and Roasted Coffee Oils (Coffea arabica L.) and their Polar Fractions

POTENTIAL OF ACEH ARABICA COFFEE EXTRACT (Coffea arabica L.) IN REJUVENATION OF AGING SKIN IN RAT

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