Phytochemical Characterization, Antimicrobial Activity, and Antioxidant Potential ofEquisetum hyemaleL. (Equisetaceae) Extracts

Abstract

Equisetum hyemale species is considered a medicinal plant used in the form of infusions to combat infectious or inflammation diseases and also diuretic effects, presenting several compounds related to these actions. In previous studies different species of Equisetum showed several phenolic compounds. The objective of this study was, for the first time, based on phytochemistry analysis to evaluate the antioxidant and antimicrobial activity. The 70% ethanolic and methanolic extracts of E. hyemale were characterized by spectrophotometric and high-performance liquid chromatography with pulsed amperometric detector analyses, as well as its antioxidant potential based on the scavenger activity of 2,2-diphenyl-1-picrylhydrazyl (DPPH). In addition was verified the antimicrobial activity by broth microdilution technique against bacteria and fungi. The extracts showed phytochemical similarity, which demonstrated the presence of phenolic compounds, the scavenging activity for free radicals was about 30% and was observed better antifungal activity against dermatophyte fungi, with minimum inhibitory concentration and minimum fungicidal concentration of 0.62 mg/mL to Trichophyton rubrum and Microsporum canis. The extracts exhibits great potential to therapeutic applications or product development, since both possess antifungal activity and antioxidant action associated with little difference in their phytochemical composition.

Phytochemistry and Pharmacology of the Genus Equisetum (Equisetaceae): A Narrative Review of the Species with Therapeutic Potential for Kidney Diseases

“…Moreover, the alkaloid palustridiene was the only one found in this species in the plant's acid extract in the study conducted by Tipke et al [56]. e hydroalcoholic extract from aerial parts of E. hyemale L. was characterized by Queiroz et al [61] by spectrophotometric and HPLC methods with pulsed amperometric detector (PAD) analyses. Phenolic compounds were detected and identified as gallic acid, tannic acid, chlorogenic acid, and caffeic acid.…”

“…Besides, regarding the antimicrobial potential of another species, E. hyemale, two articles were found. e first was contributed by Queiroz et al [61], who showed an antifungal activity of the extract against dermatophyte fungi (Trichophyton rubrum and Microsporum canis).…”

Biochemical, Phytochemical and Antioxidant Composition of Equisetum debile Roxb

“…Previous studies concerning the scavenger activities of Equisetum arvense, Equisetum ramosissimum L., and Equisetum telmateia L. showed high scavenger abilities against DPPH, NO, and OH radicals and also high total antioxidant capacity according to the fluorescence recovery after photobleaching method [39]. The methanolic extract of E. hyemale, using DPPH method, exhibited a percentage of antiradical activity of 24.29% at the concentration of 100 ug/mL [40,41]. The antioxidants are the compounds which prevent the oxidative damage to macromolecules by scavenging the free radicals produced in various biochemical…”

Antioxidant and Antiproliferative Activity of the Ethanolic Extract of Equisetum myriochaetum and Molecular Docking of Its Main Metabolites (Apigenin, Kaempferol, and Quercetin) on β-Tubulin

“…(known commonly as horsetails) are widely distributed in Mexico, where their medicinal properties are associated with their consumption [3,4]. The medicinal effects associated with this plant include antimicrobial, antioxidant, antiproliferative, and diuretic properties [5][6][7][8]. The antiproliferative capacity of these species has been limited to E. arvense (L.), whose ethanolic extracts showed a cytotoxic effect in the lung carcinoma cell line A549 [9].…”