Phytochemical, antioxidant and antidiabetic evaluation of eight Bauhinia L. species from Egypt using UHPLC–PDA–qTOF-MS and chemometrics

Farag, Mohamed A.; Sakna, Sarah T.; El-fiky, Nabaweya M.; Shabana, M.; Wessjohann, Ludger A.

doi:10.1016/j.phytochem.2015.09.004

Cited by 78 publications

(73 citation statements)

References 42 publications

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“…Compounds 7 (luteolin-6-C-glucoside, homoorientin), 13 (quercetin-3-O-rutinoside, rutin), 14 (apigenin-6-C-glucoside, isovitexin), 15 (quercetin-3-O-glucoside, isoquercetin), 17 (kaempferol-3-O-rutinoside, nicotiflorine) and 18 (kaempferol-3-Oglucoside, astragalin) were all identified according to their retention time, mass and UV-vis characteristics by comparison with commercial standards. These compounds have also been reported in other Bauhinia species by some authors (dos Santos et al, 2014;Farag et al, 2015;Ferreres et al, 2012;Liu et al, 2016).…”

Section: Effects Of Electron Beam Irradiation On Chemical Compositionsupporting

confidence: 78%

“…Moreover, the positive identification of different rutinosides, including kaempferol-3-O-rutinoside, may suggest a rutinosyl identity for the deoxyhexosyl-hexose residue and additionally, it may also be assumed that glucose is the preferred hexose, due to different glucoside derivatives found in this samples, thus this compound was tentatively assigned as kaempferol-3-O-glucosyl-rutinoside. Peak 20 ([M−H] − at m/z 431) was identified as kaempferol-3-O-rhamnoside, taking into account previous findings by Ferreres et al (2012), Farag et al (2015 and Liu et al (2016). Similarly, and taking into account the comments above, compounds 1 Compounds 3, 16 and 17 corresponded to kaempferol derivatives and were the most abundant compounds in all samples, especially kaempferol-3-O-rutinoside.…”

Section: Nm) Peak 3 ([M−h]mentioning

confidence: 57%

“…Furthermore, this compound has also been identified in other Bauhinia species (Farag et al, 2015;Liu et al, 2016). Peaks 3, 6, 8, 16 and 20 were identified as kaempferol derivatives owing to the product ion observed at m/z 285 and UV spectra (λ max around [346][347][348][349][350] …”

Section: Compound 11 ([M−h]mentioning

confidence: 81%

“…The observation of MS 2 fragments at m/z 447 (−162 u) and 285 (−162 u), also indicated the alternative loss of each of the hexosyl moieties, respectively, pointing to their location on different positions of the aglycone. To identify the position of substitution, and based in the observation performed by other authors in other Bauhinia species (Farag et al, 2015;Liu et al, 2016), it can be assumed that the positions 3 and 7 as preferential (Ferreres, Llorach, & GilIzquierdo, 2004) correspond to a kaempferol bearing two hexosyl and one deoxyhexosyl residues. The fact that only one MS 2 fragment was released corresponding to the aglycone (i.e., m/z at 285, kaempferol) would suggest that the three sugars constitute a trisaccharide.…”

Section: Nm) Peak 3 ([M−h]mentioning

confidence: 99%

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The influence of electron beam radiation in the nutritional value, chemical composition and bioactivities of edible flowers of Bauhinia variegata L. var. candida alba Buch.-Ham from Brazil

et al. 2018

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A B S T R A C TAs edible flowers are highly perishable, irradiation technology can be applied to increase their shelf life, as also for phytosanitary purposes. Herein, flowers of Bauhinia variegata L. var. candida alba Buch.-Ham were submitted to electron beam irradiation at the doses of 0.5, 0.8 and 1 kGy, to study the effects in the nutritional and chemical profiles, and also in antioxidant, cytotoxic and anti-inflammatory activities. The petals of white flowers revealed interesting bioactive properties being kaempferol derivatives the most abundant compounds, especially kaempferol-3-O-rutinoside. The applied irradiation doses did not highly affect the nutritional profile. No changes were produced in cytotoxicity, but the anti-inflammatory activity slightly decreased. However, the antioxidant activity was increased, especially in the dose of 0.5 kGy, in agreement with the higher content in phenolic compounds found at this dose.

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Section: Effects Of Electron Beam Irradiation On Chemical Compositionsupporting

confidence: 78%

Section: Nm) Peak 3 ([M−h]mentioning

confidence: 57%

Section: Compound 11 ([M−h]mentioning

confidence: 81%

Section: Nm) Peak 3 ([M−h]mentioning

confidence: 99%

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The influence of electron beam radiation in the nutritional value, chemical composition and bioactivities of edible flowers of Bauhinia variegata L. var. candida alba Buch.-Ham from Brazil

et al. 2018

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“…O restante, 31 artigos foram utilizados na pesquisa, e apresentados na Tabela 1, em que estão listadas as espécies de Bauhinia L. que possuem ensaios relacionados à atividade hipoglicemiante e respectivas fontes de referência. RUSSO et al, 1990;SILVA et al, 2002a;PEPATO et al, 2002, JORGE et al, 2004SOUZA et al, 2004;LINO et al, 2004;VASCONCELOS et al, 2004;MENEZES et al, 2007;CUNHA et al, 2010;CURCIO et al, 2012;CAZAROLLI et al, 2013;FARAG et MARTINEZ et al, 2009;MESHRAM et al, 2013B. thonningii OJEZELE, ABATAN, 2011B.…”

Section: Resultsunclassified

Experimental Studies With Species of Bauhinia (Fabaceae) to Evaluate the Antidiabetic Activity

Paula

2016

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RESUMO:Modelos de estudo in vivo e in vitro e em enzimas/receptores são utilizados quando se pretende comprovar a ação farmacológica de um determinado extrato e/ou princípio ativo obtido de plantas, além de elucidar o mecanismo de ação. O objetivo deste estudo foi realizar um levantamento da literatura sobre quais os ensaios que já foram realizados com plantas do gênero Bauhinia L. para verificar a atividade hipoglicemiante, e quais as espécies pesquisadas. Para isso, foi realizado uma revisão da literatura através de busca eletrônica nas bases de dados Pubmed, Science direct, Lilacs e na biblioteca eletrônica Scielo, publicados no período de 1995 à 2015 (20 anos), utilizando como descritores "Bauhinia" and "extract" and "hypoglycemic" or " seus correspondentes em português, "Bauhinia" e "extrato" e antidiabetic" "hipoglicêmica" ou "antidiabético". Foram localizados artigos relacionados à pesquisa com doze espécies de Bauhinia L. A Bauhinia forficata é a que mais apresenta estudos sobre o tema, sendo localizado 13 artigos, seguida da B. variegata com 4 estudos. Foi possível verificar que pouco se conhece sobre a atividade hipoglicemiantes das espécies de Bauhinia L., e que mais estudos são necessários para comprovar o uso popular. Palavras-chave: pata de vaca, planta medicinal, diabetes ABSTRACT:In vivo and in vitro and in enzymes / receptors study models are used when you want to prove the pharmacological action of a particular extract and / or active ingredient from plants, as well as elucidate the mechanism of action. The aim of this study was to survey the literature on which trials have already been conducted with the genus Bauhinia L. plans to check the hypoglycemic activity, and what the surveyed species. For this, we conducted a literature review through electronic search on Pubmed, Science direct, Lilacs and electronic library SciELO, published from 1995 to 2015 (20 years), using as keywords "Bauhinia" and "extract "and" hypoglycemic "or" Antidiabetic "their equivalents in Portuguese," Bauhinia "and" extrato "and" hipoglicêmico "or" anti-diabético". Research-related articles were found with twelve species of Bauhinia L. The Bauhinia forficata is the one that presents studies on the subject, being located 13 articles, followed by B. variegata , 4 studies. It observed that little is known about the hypoglycemic activity of the species of Bauhinia L., and that further studies are needed to confirm the popular use.

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Qualitative and quantitative analysis of chemical constituents in Ardisiae Japonicae Herba

Gao²,

et al. 2017

J. Sep. Sci.

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Ardisiae Japonicae Herba is a well-known traditional Chinese medicine for the treatment of bronchitis conjunctivitis, pneumonia, and trauma. In this work, a high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry method was first established for the separation and structural identification of the chemical constituents in Ardisiae Japonicae Herba. A total of 15 compounds including coumarins, flavonoid glycosides, and catechins were identified or tentatively characterized based on their chromatographic behaviors and mass spectral fragmentation and by comparisons with the reference standards. Furthermore, a simple high-performance liquid chromatography with diode array detection method was developed for the simultaneous determination of five major constituents. Results obtained from method validation, including linearity, precision, repeatability, stability, and recovery, showed that the established method was reliable and accurate. Bergenin and quercitrin were found to be the most abundant constituents and could be served as chemical markers for quality control of Ardisiae Japonicae Herba.

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Phytochemical, antioxidant and antidiabetic evaluation of eight Bauhinia L. species from Egypt using UHPLC–PDA–qTOF-MS and chemometrics

Cited by 78 publications

References 42 publications

The influence of electron beam radiation in the nutritional value, chemical composition and bioactivities of edible flowers of Bauhinia variegata L. var. candida alba Buch.-Ham from Brazil

The influence of electron beam radiation in the nutritional value, chemical composition and bioactivities of edible flowers of Bauhinia variegata L. var. candida alba Buch.-Ham from Brazil

Experimental Studies With Species of Bauhinia (Fabaceae) to Evaluate the Antidiabetic Activity

Qualitative and quantitative analysis of chemical constituents in Ardisiae Japonicae Herba

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