Phytochemical and cytotoxic study in Quisqualis indica volatile oil cultivation in Iraq

Abstract

The volatile oil is metabolites product from some plant have biological activities such as antimicrobial ,antioxidant and have viability for reduced cancer cell ,through inhibit cell proliferation ,for this reason This study was set to extraction volatile oils from Inflorescences of Qusiqualis indica plant cultivation in Iraq from tow season (spring ,autumn)and identification of the Chemical compounds of these ( using GC-MS ) ,The cytotoxic effect of two seasons volatile oils on human lung cancer cells A549 compared with normal REF cell cells were studied at concentrations (5,6,12,25,50)μl/ml and the programmed cell death (apoptosis) tested for cells lines and measured P53 gene ,Caspase-8 expression levels. The results showed significant quantitative and quantitative in two seasons oils ,and there were significant differences in the degree of cytotoxicity between the two oils ,where is at the concentration (50 μl/ml)they have the highest effects of(A549)cells compared with REF cells ,while the higher apoptosis effect at (25 μl/ml) concentrate for A549 compared with REF.

Evaluation of Antioxidants, Antibacterial and Antidiabetic Activities of Aqua-alcoholic Marjoram Extract

“…Recently, several studies about plant extracts were conducted that included their properties in nano size, antioxidant [1][2][3][4] , their phenolic content , and their cytotoxicity due their bio-activities and safety [5][6][7] , in addition to other studies that concerned with diabetes complications [8][9][10][11] . Marjoram is an aromatic herbaceous plant and it is from the famous mint group and contains many vitamins and minerals, as well as volatile oils, flavonoids, hydroquinone glycosides, sugars, and triterpenes.…”