“…Abundant evidence showed that various diseases like obesity, diabetics, colorectal cancer and irritable bowel syndrome accompanied by changes of intestinal microbes. Also, intestinal microbes disorder plays a significant role in the pathogenesis of these diseases (Liu, 2018, Liu et al, 2015, Aziz et al, 2013, Wang et al, 2017a, Wang et al, 2017b, Wang et al, 2014, Bäckhed et al, 2004, Koeth et al, 2013, Hooper and Gordon, 2001, Larsson et al, 2012, Qin et al, 2010, Qin et al, 2012, Ley et al, 2006, Tremaroli and Bäckhed, 2012, Mehvish and Barkat, 2018a, Mehvish and Barkat, 2018b).…”