Phytochemical and antibacterial studies of extracts of </i>Flabellaria

Abstract

The phytochemical and antibacterial studies of the leaf extracts of Flabelleria paniculata cav, have been investigated. Antibacterial activity was investigated using Staphylococcus. aureus, Pseudomonas aerugniosa, Eustaricia coli and Klabellia pneumoniae. The petroleum ether extract was completely inactive. At the concentration of 50mg/ml aqueous extract produced zone of inhibition of 3mm (S. aureus,) and 2mm (Ps. aerugniosa) but was inactive against E. coli and K. pneumoniae. At 10mg/ml chloroform extract produced zone of inhibition of 3mm (S. aureus), 2mm (Ps. aerugniosa), 2mm (F. coil) and 3mm (K. pneumoniae). Chloroform extract showed MIC values of 1 .75 mg/ml and 2mg/ml for Ps. aerugniosa and S. aureus respectively. Saponins, cardenolides, alkaloid and tannins were detected in the leaf. This study justifies the local uses of the plant for the treatment of skin diseases and wounds.

Anti-infective and wound healing properties of <i>Flabellaria paniculata</i>

“…Fresh leaves of F. paniculata were collected as described previously (Abo and Olugbuyiro, 2004). Hundred grams of dried (45°C) F paniculata were powdered and macerated with 70% methanol.…”

“…In a previous paper (Abo and Olugbuyiro, 2004), we reported on the phytochemical and antibacterial studies of Flabellaria paniculala. To further investigate the biological activities of the species, we report its effect on normal wounds and infected wounds in rats.…”

comparison of Antimicrobial Effects of Mezoneuron benthamianum, Heliotropium indicum and Flabellaria paniculata on Candida species

“…F. paniculata belongs to the family malpigbiaceae. It is a climbing shrub of 3-15 meters high; the leaves are slivery under surface with white pale pink flowers 14 . It is an herb indigenous to the tropical Africa.…”

Evaluation of Antibacterial Activity of <i>Prosopis Juliflora</i> (Sw.) Dc. Leaves

“…(15 mm), S. typhi (15 mm), S. aureus (13 mm) and P. aeruginosa (14 mm), but the petroleum ether fraction showed no activity on all test organisms similar in our study (Ayepola and Adeniyi, 2008). Similarly, petroleum ether fraction of Flabellaria paniculata leaf extracts (Abo et al, 2004) and Lumnitzera racemosa twigs (D'Souza et al, 2010) were also completely inactive against tested bacterial strains. Similar results were found in the chloroform soluble fraction of Acacia senegal which was inactive against K. pneumoniae and S. aureus in all three concentrations (1000 μg/ml, 3000 μg/ml, and 5000 μg/ml) whereas, the n-hexane soluble fraction showed dissimilar results by displaying activity against K. pneumoniae (Mudi and Salisu, 2009).…”

“…In an another study the chloroform fraction of the leaf extracts of Flabellaria paniculata demonstrated antibacterial potential against S. aureus, P. aeruginosa, E. coli and K. pneumoniae (Abo et al, 2004) whereas, the n-butanol fraction obtained from twigs of Lumnitzera racemosa demonstrated good antibacterial activity at 50 µg/ml concentration against E. coli, K. pneumoniae, P. aeruginosa, S. typhi and S. aureus with a different degree of inhibition (D'Souza et al, 2010). In another study, the hexane fraction of Curcuma mangga showed 15.0 mm inhibition zone against P. aeruginosa, 9.5 mm against S. aureus and 13.5 mm against B. subtilis at concentration 500 mg/ml while the ethyl acetate fraction showed inhibition against P. aeruginosa, S. aureus and B. subtilis with inhibition zones 11.5, 9.0, 13.7 mm respectively at concentration 500 mg/ml (Philip et al, 2009).…”