Phytochemical and antibacterial activity of &lt;i&gt;ficus iteophylla&lt;/i&gt; linn leaves (moraceae)

Ahmadu, AA; Akpulu, IN; Abubakar, M. G.; Hassan, H. N. A.; Sule, MI

doi:10.4314/njpr.v5i1.53568

Cited by 2 publications

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“…The bark is used to treat dysentery, rheumatic pain and as pain killer (Burkill, 1997). The leaf part was reported to have antibacterial activity (Ahmadu et al, 2006). Previous phytochemical studies on the leaf led to isolation of two furanocoumarines, psoralen and bergapten (Ahmadu et al, 2004), two flavonoid glycosides which are Kaempferol-3-o-rutinosides and Quercitin-3-o-rutinosides (Ahmadu et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

“…The leaf part was reported to have antibacterial activity (Ahmadu et al, 2006). Previous phytochemical studies on the leaf led to isolation of two furanocoumarines, psoralen and bergapten (Ahmadu et al, 2004), two flavonoid glycosides which are Kaempferol-3-o-rutinosides and Quercitin-3-o-rutinosides (Ahmadu et al, 2006). The present study to the best of our search is the first report to evaluate the leaf part of the plant for analgesic and inflammatory activities.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of analgesic and anti-inflammatory effects of ethanol extract of <i>Ficus iteophylla</i> leaves in rodents

Sule²,

Am³

et al. 2011

Afr. J. Trad. Compl. Alt. Med.

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This study was undertaken to investigate the leaf part of the plant for analgesic and anti-inflammatory. The ethanol extract of Ficus iteophylla leaves (100, 200, and 400mgkg -1 , i.p) was evaluated for analgesic and anti-inflammatory activities. The analgesic effect was studied using acetic acid-induced abdominal constriction and hot plate test in mice, while the antiinflammatory effect was investigated using carrageenan induced paw oedema in rats. The ethanol extract at 100mgkg-1 , and 400mgkg -1 significantly (P< 0.05) inhibited acetic acid induced writhes by 1.50 ± 0.43, 3.0 ± 0.82 and 1.0 ± 0.82 respectively. It also exhibited significantly (P< 0.05) anti-inflammatory by 0.11 ± 0.02, 0.11 ± 0.03, 0.08 ± 0.01 respectively. The preliminary phytochemical screening of the plant extract revealed the presence of flavonoids, steroids, tannins and saponins while the effect of flavonoids, steroids and tannins on analgesic and inflammatory has been reported. The intraperitoneal median lethal dose (LD 50 ) value of the extract was found to be 3807.8 mgkg -1 body weights. The result obtained from this study shows that the extract of Ficus iteophylla contained phytochemical constituents with analgesic and anti-inflammatory activities, therefore the leaf part of the plant could be used in the management of pain and inflammatory conditions.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of analgesic and anti-inflammatory effects of ethanol extract of <i>Ficus iteophylla</i> leaves in rodents

Sule²,

Am³

et al. 2011

Afr. J. Trad. Compl. Alt. Med.

Self Cite

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“…The analgesic [3]and anti-inflammatory [4], antidiarrhic and antipyretic properties, the anxiolytic or sedative activities [5]and antidiabetic activity [6]have been reported. Ahmadu et al [7]identified three flavonoid glyscosides from the ethanolic extract of the plant and the flavonoids are quercetin 3-O-αarabinose (guajavarin), quercetin and quercetin…”

Section: Introductionmentioning

confidence: 99%

Effects of Sub-acute Oral Administration of Ethanolic Leaf Extract of Byrsocarpus coccineus on Haematology and Serum Biochemical Parameters of Wistar Albino Rats.

Oladele

2020

JVBS

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Byrsocarpus coccineus is an indigenous herb widely dispersed in tropical Africa and commonly known as Crimson thyme. The leaf and root of the plant is noted to possess medicinal benefits in traditional medicine of the Western part of Nigeria. The plant has been reported to possess analgesic, antiplasmodial, inflammatory, antidiarrhic and antipyretic activities. The present study was therefore aimed at determining the sub-acute toxicity of ethanolic leaf extract of Byrsocarpus coccineus. The ethanolic leaf extract of the plant was administered orally at 250, 500, and 1000 mg/kg to three groups A, B and C of Wistar rats respectively for 14 days while the control group D was administered orally with 3ml/kg of distilled water. Blood samples were then obtained from the anaesthetized rats for haematology and serum biochemistry. The result obtained from serum analyses showed a significant increase (p<0.05) in the levels of blood urea nitrogen and creatinine levels while the increase in alkaline phosphatase is not significant for the treated groups B and C compared with the control. It was therefore concluded that high doses of the extract may have untoward effects on the kidney and therefore, the use of the plant extract in high doses should be discouraged.

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Phytochemical and antibacterial activity of <i>ficus iteophylla</i> linn leaves (moraceae)

Cited by 2 publications

References 0 publications

Evaluation of analgesic and anti-inflammatory effects of ethanol extract of <i>Ficus iteophylla</i> leaves in rodents

Evaluation of analgesic and anti-inflammatory effects of ethanol extract of <i>Ficus iteophylla</i> leaves in rodents

Effects of Sub-acute Oral Administration of Ethanolic Leaf Extract of Byrsocarpus coccineus on Haematology and Serum Biochemical Parameters of Wistar Albino Rats.

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