Physiological Features of Platelets in Milk and Vegetable Nutrition Piglets

Abstract

A very important mechanism for maintaining homeostasis in the animal body is platelet hemostasis. The level of his activity very strongly determines the rheology of blood in the capillaries and due to this the state of metabolism in the tissues. There is reason to believe that the growth and development of piglets depends on the level of functional activity of platelets. For this reason, studies of the age-related dynamics of platelet activity in piglets during early ontogeny are of great importance. In the study, it was established that piglets of milk and vegetal nutrition showed an increase in the adhesive, aggregation and secretory capacity of platelets. The main reason for this may be an intensification of the work of receptor and postreceptor mechanisms of platelets. This was characteristic of piglets during dairy and plant nutrition in the same degree with respect to strong and weak inducers of platelet aggregation. At the base of the revealed increase in the activity of platelets in piglets throughout the course of the observation, the increase in the synthesis of thromboxane in platelets was largely due to the increase in the activity of cyclooxygenase and thromboxane synthetase in them and activation of the secretion of ADP from them. The increase in hemostatic activity of platelets in piglets during the phase of milk and plant nutrition should be considered an important regulator of their microcirculation and metabolism in tissues under changing conditions of existence.