Physiological Activities of the Hot Water Extract from Eriobotrya japonica Lindl.

정유석,; 정희경,; 윤광섭,; 김명옥,; 홍주헌,

doi:10.3746/jkfn.2009.38.8.977

Cited by 18 publications

(7 citation statements)

References 5 publications

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“…The ABTS radical scavenging activity was measured as previously described (Jeong et al, 2009). PBS (pH 7.4) was used to prepare a 1:1 dilution of 2.45 mM ABTS potassium persulfate (7 mM) dissolved in distilled water.…”

Section: Abts Scavenging Activitymentioning

confidence: 99%

Antioxidant activity and immune-enhancing effect of aqueous leaf Elaeagnus multiflora Thunb

Kim¹,

Kim²,

Lee³

et al. 2020

Korean J. Food Preserv.

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In this study, we aimed to investigate the antioxidant and immunopotentiating effects of leaves of cherry elaeagnus (Elaeagnus multiflora, Em). The leaf, stem, and root of Em have been used in Kampo medicine. There are data on the therapeutic effects of Em fruit, but no information on its leaves. We thus investigated the antioxidant and immunopotentiating effects of Em leaf extract. Balb/c mouse spleen cells were treated with concanavalin A and hot aqueous Em leaf extract (50, 100, and 200 µg/mL), and the effects on spleen cell proliferation and the secretion of interleukin (IL)-2, IL-4, and IL-10 were evaluated. A concentration-dependent increase in the secretion of IL-2 and IL-4 cytokines was observed, with concentrations of 1.86 pg/mL of IL-2 and 37.63 pg/mL of IL-4 when cells were treated with 200 µg/mL of the extract. Natural killer (NK) cell activity was determined based on a co-culture of spleen cells and Yac-1 cells. NK activity gradually increased in a concentration-dependent manne. Further, 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity was 58.5% and 2,2ʹ-azino-bis(3-ethylbenzothiazoline-6sulfonic acid) radical scavenging activity was 78.2% with an extract concentration of 200 µg/mL. The high antioxidant activity of the hot water extract of Em leaves suggests their potential therapeutic value and warrants further studies.

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Section: Abts Scavenging Activitymentioning

confidence: 99%

Antioxidant activity and immune-enhancing effect of aqueous leaf Elaeagnus multiflora Thunb

Kim¹,

Kim²,

Lee³

et al. 2020

Korean J. Food Preserv.

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“…Especially, the leaves of E. japonica have been widely used as a traditional medicine with beneficial effects as an expectorant, for hemoptysis, quenching thirst, chronic bronchitis, edema, septic settlement, and a strong stomach (Shin et al, 2012). According to recent study, it has been reported to be the effect of various component analyses (Bae et al, 2002;Bae et al, 2005), gastroenteritis improvement (Takuma et al, 2008), antioxidant (Hwang et al, 2010;Park et al, 2008;Jeong et al, 2009), anticancer (Kim et al, 2009c;Lee et al, 2004), antibacterial (Bae et al, 2002;Bae et al, 2005;, anti-inflammatory (Shin et al, 2012;Kim et al, 2009a;Banno et al, 2005), anti-diabetic (Kim et al, 2009b;Kim et al, 2006;Chen et al, 2008), skin whitening and skin allergy inhibition (Sun et al, 2007). Also, it has garnered attention in various herbal ingredients markets because it is safe and does not have side effects (Hwang et al, 2010;Lee et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Developed validation for simultaneous determination of three Di-caffeoylquinic acid derivatives from the Leaf of Eribotrya japonica Lindl. by HPLC-DAD

2022

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The aim of this study was to developed HPLC simultaneous analysis method for the determination of Caffeoylquinic acid isolated from the leaf of Eribotrya japonica Lindl. extract. The phenolic compounds in E. japonica leaves were isolated and identified by HPLC, NMR, Mass etc. The quantitative analysis was carried out HPLC-DAD using C18 column with gradient elution of water and acetonitrile at 280 nM for 60 min. The method was successfully validated by specificity, LOD (linearity, limit of detection), LOQ (limit of quantification), precision and recovery. The three phenolic compounds were isolated from E. japonica leaves including 5-Caffeoylquinic acid (5-CQA), 4-Caffeoylquinic acid (4-CQA) and 3-Caffeoylquinic acid (3-CQA). In a quantitative analysis of three phenolic compounds were 3-CQA 7.82-14.48 µg/mL, 4-CQA 3.75-12.58 µg/mL and 5-CQA 3.60-7.82 µg/mL using the standard chemicals, respectively. The developed HPLC validation method would be applicable for simultaneous quantitative analysis of phenolic compounds in E. japonica leaves extracts.

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“…그 주요 성분은 nerolidol, ferulic acid이며, 그 외에 ursolic acid, oleanolic acid, β-carotene, kaempherol, amygdalin, malic acid, citric acid, tannin 등이 함유되어 있으며 항당뇨, 항산화, 항염 증, 항암, 항균 효과, 항바이러스 효과가 있는 것으로 알려 져 있다. 또한 비파엽에 함유된 polyphenol, flavonoid 등의 생리활성 물질은 체지방형성을 억제하고, 체내 지질대사 개 선과 심혈관계 질환 예방에 효과가 있다는 보고가 있다 [10][11][12][13][14][15][16][17][18][19][20][21] . 5).…”

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The Efficacy of Eriobotryae Folium Pharmacopuncture on Local Fat of High Fat Diet Induced Obesity Mice※

Roh¹,

Yim²

2013

The Acupuncture

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Objectives : This study was designed to investigate the anti-obesity effects in local area adipose tissue using by pharmacopuncture of Eriobotryae Folium on mice fed high fat diet. Methods : Male ICR mouse were divided into three groups. Normal diet group (N), High-fat diet(HFD) group, HFD+E(pharmacopuncture of the Eriobotryae Folium) group for 8 weeks. HFD+E group was injected in the concentration of 50 mg/kg once a day for 4 weeks and every other day during the next 4 weeks. We measured body weight, food intake, absolute weight and relative weight in the liver and adipose tissue. Also, we analyzed hematological levels and histopathological changes on adipose tissue. Results : 1. We observed no difference in food intake among three groups.2. HFD+E group significantly decreased body weight gain and absolute weight and relative weight in the liver and adipose tissue compared with HFD group. 3. Blood AST and ALT were no differences among the experiment groups. However, HFD group was significantly increased higher TG, TC, HDL and LDL than in N group and HDL/LDL ratio was remarkably decreased. On the other hand, HFD+E group was significantly decreased in obesity markers and HDL/LDL ratio was remarkably increased. 4. Levels of adiponectin in serum of HFD+E group was remarkably increased compared with those of HFD group. 5. HFD group was significantly decreased compared with N group in adipocyte number. Compared with the HFD group, HFD+E group was displayed a significant increase by adipocyte number. Conclusions : We suggest that pharmacopuncture of the Leaves of Eriobotrya japonica can play the anti-obesity effects in local area adipose tissue.

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Physiological Activities of the Hot Water Extract from Eriobotrya japonica Lindl.

Cited by 18 publications

References 5 publications

Antioxidant activity and immune-enhancing effect of aqueous leaf Elaeagnus multiflora Thunb

Antioxidant activity and immune-enhancing effect of aqueous leaf Elaeagnus multiflora Thunb

Developed validation for simultaneous determination of three Di-caffeoylquinic acid derivatives from the Leaf of Eribotrya japonica Lindl. by HPLC-DAD

The Efficacy of Eriobotryae Folium Pharmacopuncture on Local Fat of High Fat Diet Induced Obesity Mice※

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