1993
DOI: 10.1016/0735-1097(93)90212-j
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Physics and engineering of transcatheter cardiac tissue ablation

Abstract: Ablation of arrhythmogenic cardiac tissues has emerged as one of the most important advances in cardiac electrophysiology. With the introduction of transcatheter ablation, the treatment of ventricular tachycardia, Wolff-Parkinson-White syndrome and other cardiac arrhythmias has progressed from an expensive and painful surgical therapy accompanied by a long recovery period to the less expensive, less traumatic transcatheter approach. The feasibility of cardiac ablation, along with the increasing number of physi… Show more

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Cited by 62 publications
(24 citation statements)
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“…Durin g c lin ical ap plication of rad iofreque ncy, blood is also e xpose d to the cath e ter an d on ly a portion of th e tip is in contact with tissue . Furth e rm ore , blood can be trappe d be twe e n the e le ctrode an d tissue [ 19] . Coag ulum is form e d un de r th e se conditions aroun d th e tip of th e cath e te r an d th e im pe dan ce incre ase s, as we observe d in our m ode l. More ove r, sinc e we foun d n o sign i® can t diffe re n ce s be twe e n th e two¯ow conditions in our m ode l, th is could n ot be con side re d the m ain variab le in this study.…”
Section: Discussionmentioning
confidence: 99%
“…Durin g c lin ical ap plication of rad iofreque ncy, blood is also e xpose d to the cath e ter an d on ly a portion of th e tip is in contact with tissue . Furth e rm ore , blood can be trappe d be twe e n the e le ctrode an d tissue [ 19] . Coag ulum is form e d un de r th e se conditions aroun d th e tip of th e cath e te r an d th e im pe dan ce incre ase s, as we observe d in our m ode l. More ove r, sinc e we foun d n o sign i® can t diffe re n ce s be twe e n th e two¯ow conditions in our m ode l, th is could n ot be con side re d the m ain variab le in this study.…”
Section: Discussionmentioning
confidence: 99%
“…Power delivery and tip temperature are the main manipulated variables in RF ablation. While, at a given electrode tip size, the amount of power is the determinant for lesion size, 13 excessive tip temperature leads to char and/or coagulum formation and to a rapid increase of impedance that hampers efficient transmission of RF energy 2,14 . Rise of impedance is observed when there is formation of coagulum at the catheter tip or imminent steam popping and requires termination of the RF application.…”
Section: Discussionmentioning
confidence: 99%
“…This heating is a direct function of the current density at the catheter ablation electrode onto the myocardial interface extending a few millimeters into the tissue. 2,3 Resistive heating increases the tissue's kinetic energy by virtue of increasing molecular movement. In contrast, cryotechnologies Q5 remove heat from tissues, lowering molecular movement and stored kinetic energy, which results in tissue cooling and ice formation.…”
Section: Introductionmentioning
confidence: 99%