Physicochemical Study and Quantitative Analysis Swarna Makshika Bhasma.

Bhardwaj, Rajni; Smita, Johar; Kapila, Amit

doi:10.32553/ijpba.v9i1.172

Cited by 3 publications

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“…By Fourier Transform Infrared Spectroscopy (FTIR) chemical bonds will be identified in MSP and MSB [23]. With the help of X-Ray Diffraction (XRD) the crystalline structures of the molecule will be recognized in both the samples that are MSP and MSB [24]. GC-MS technique will be used to analyze complex organic and biochemical mixtures between MSP and MSB [25].…”

Section: Discussionmentioning

confidence: 99%

Pharmaceutico-Analytical Study of Muktashukti Pishti and Muktashukti bhasma and Comparative Evaluation of their Relative Oral Bioavailability

Kamble

Wanjari

Rathi

et al. 2021

JPRI

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Background: Shukti (Oyster) is a very commonly occurring calcium form. It is rich source of calcium & minerals. As per text it can be converted into two forms which are bhasma (calcinated ash) and pishti (powdered form without agni).These forms may have different rate of absorption. This needs to be studied. Aim: To study Pharmaceutico-analytical study of Muktashukti pishti & Muktashukti bhasma and comparative evaluation of their relative oral bioavailability. Materials and methods: The two formulations will be prepared from shukti (oyster). By triturating with Gulabjala Muktashukti pishti will be prepared and by traditional puta method Muktashukti bhasma will be prepared. The prepared formulations will be assessed for Bhasma Pariksha mentioned in Ayurveda. Organoleptic characters, physicochemical parameters and Particle size distribution analysis, SEM-EDX (Scanning Electron Microscopy, Energy Dispersive X-Ray Analysis), FTIR (Fourier-transform infrared spectroscopy), XRD (X-Ray Diffraction), GCMS (Gas Chromatography Mass Spectrometry) will be evaluated. To assess the relative oral bioavailability of Muktashukti pishti & Muktashukti bhasma study will be conducted in healthy volunteers and will be compared with the standard calcium supplement. The study will be conducted in between two test groups and standard group. Observation and results: The analytical parameters will be assessed and compared in Muktashukti bhasma and Muktashukti pishti. For relative oral bioavailability Blood serum calcium will be assessed in all three groups. By applying unpaired “t” Test, One-way ANOVA the statistical significance can be measured. Conclusion: The pharmaceutical & analytical study of Muktashukti pishti and Muktashukti bhasma will provide the standard parameters and clinical comparative evaluation with standard will generate evidence for better bioavailability.

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Section: Discussionmentioning

confidence: 99%

Pharmaceutico-Analytical Study of Muktashukti Pishti and Muktashukti bhasma and Comparative Evaluation of their Relative Oral Bioavailability

Kamble

Wanjari

Rathi

et al. 2021

JPRI

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“…[14,15] Field emission scanning electron microscopy with EDX (FESEM-EDS) was also used in quantitative analysis of Swarna Makshika Bhasma and Rajat Bhasma. [16,17] SEM-EDX analysis along with pharmacodynamics study of any mineral compound can provide the accurate estimation of bioavailability as well as safety dose estimation of study compound. [18,19] SEM-EDX quantitative and qualitative analysis is also useful to maintain the inherent quality of the ancient Indian system of medicine.…”

Section: Edx Microanalysis or Energy-dispersive Spectroscopy (Eds)mentioning

confidence: 99%

Untitled

2023

AJP

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Ayurveda is a natural system of medicine, which is acceptable worldwide now days. Most of the medications used in this traditional system belong to natural drugs derived from the plants and other natural resources. These naturally derived antimicrobial drugs are equally effective as the other synthetically designed drugs of other medicinal systems against the different microbes. A detailed compositional analysis of any drug is very necessary to establish its role. Energy-dispersive X-ray (EDX) or energy-dispersive spectroscopy is a kind of microanalysis of any elemental structure. It is based on the detection of characteristic X-rays generated under electron microscopy. It provides both quantitative as well as qualitative information in elemental analysis. It is very important and useful technique to study a new drug to understand the drug delivery as well as nanoparticles in composition of any drug. In the present study, we have used a plant based extract antimicrobial drug named Fifatrol for detailed compositional analysis by EDX microanalysis under scanning electron microscope to see the different proinflammatory and anti-inflammatory elements such as Ca, S, O, Na, and B.

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“…Ayurveda provides a list of tests for the efficacy of the bhasmikarana process. The tests are essentially qualitative and ensure that the Resulting drug is very fine (small grains), has no metallic shine and does not alloy with silver even at higher temperature to which it was subjected (4)(5)(6)(7) . However, these qualitative tests do not provide any quantitative information about the composition and the structure of the final drug.…”

Section: December 2023mentioning

confidence: 99%

“…The Ayurvedic Bhasma is checked for impurities and high quality using the Results of the physicochemical examination. Researchers looking into the effectiveness of Ayurvedic Bhasma and its possible applications in treating a range of illnesses should find this information to be very useful (6) .…”

Section: Physicochemical Evaluationmentioning

confidence: 99%

Phytochemically tailored zinc based ayurvedic nano-medicine: Therapeutic Importance and Prospects

Mishra,

Tripathi

2023

UJPAH

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Ayurveda, a time honoured traditional system of medicines, has thrived on its profound understanding of the correlation between human body constitution and the elements of the universe. Yashad Bhasma (Zinc Oxide), a unique Ayurvedic metallic preparation, has been employed for centuries in treating various ailments, offering a holistic approach as an immune booster and a healing agent. Phytochemically tailored Zinc based herbomineral novel preparations/formulations have been explored to be an important wide spectrum therapeutic, based on blended pharmacy methods. The article introduces the concept of zinc-based Ayurvedic nano-medicine, emphasizing the therapeutic potential of zinc oxide nano-particles, an evidence based herbo-mineral formulation which has embraced reverse pharm. principles. There lies resemblance between Ayurvedic Bhasmas and chemically metal oxides, Physicochemically, Biochemically and also in-turn physiologically. The trans-formation of metallic zinc into assimilablezinc oxide as per modified Ayurvedic methodology may be of paramount significance. This conversion not only eliminates the toxicity of the metal but also enhances biocompatibility, paving the way for targeted drug delivery and medical imaging on the lines of ADMET. Furthermore, the study calls for comprehensive standardization measures, addressing qualitative and quantitative aspects. The article highlights the necessity of scientific strategies to navigate challenges in Yashad Bhasma research, ensuring its safety, quality, and medicinal efficacy by phytochemical blending. The research advocates for a harmonious blend of traditional wisdom and modern scientific rigor to propel Ayurvedic medicinal system, specifically Yashad Bhasma, into mainstream healthcare. Standardization and redesigning may emerge as the cornerstone for bridging the gap between ancient healing practices and contemporary healthcare to foster global acceptance and utilization of Ayurvedic treatments, accepted as have been realised, practiced and proved during pandemic Corona as Repurposed therapeutic strategy.

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Physicochemical Study and Quantitative Analysis Swarna Makshika Bhasma.

Cited by 3 publications

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Pharmaceutico-Analytical Study of Muktashukti Pishti and Muktashukti bhasma and Comparative Evaluation of their Relative Oral Bioavailability

Pharmaceutico-Analytical Study of Muktashukti Pishti and Muktashukti bhasma and Comparative Evaluation of their Relative Oral Bioavailability

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Phytochemically tailored zinc based ayurvedic nano-medicine: Therapeutic Importance and Prospects

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