Physicochemical properties of an anticonvulsant drug sodium valproate in aqueous and in mixed aqueous solutions at different temperatures

Mondal, Sudip; Dhondge, Sudhakar S.; Paliwal, L. J.; Tangde, Vijay M.; Jengathe, Santosh P.

doi:10.1016/j.jct.2015.06.025

Cited by 46 publications

(12 citation statements)

References 54 publications

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“…Our value of absolute viscosity of 0.06 molÁkg À1 of aqueous NaCl solution compares with that of Mondal et al [3] and Banipal et al [55] respectively at 298.15 K. The value of absolute viscosity of 0.06 molÁkg À1 of aqueous D-glucose solutions has been compared with that of Mondal et al [3], Banipal et al [16]. It is observed that our values agree well with those reported by them.…”

Section: Relative Viscositysupporting

confidence: 89%

“…The values of the standard deviation, r and average absolute deviation (AAD) for apparent molar volume of the solute have been obtained using following expressions [3],…”

Section: Resultsmentioning

confidence: 99%

“…From the perusal of Table 6, it is observed that the values of the D coefficients are positive for all temperatures which arise because of the presence of solute-solute interactions at all temperatures [3,8].…”

Section: Viscosity Coefficientsmentioning

confidence: 99%

“…The relative viscosities (g r ) of the solutions can be related to the solute concentration (C) using Jones-Dole equation [3,18] as given:…”

Section: Viscosity Coefficientsmentioning

confidence: 99%

“…Also water is the host of many biochemical processes. Thus the study of the thermodynamic parameters of drug in aqueous medium and in the presence of various co-solutes such as carbohydrates, proteins, vitamins, amino acids, nucleosides, nucleotides, and inorganic salts of many ions, enhances the understanding of the molecular interactions of drug molecules [3]. Also the drug water interactions at different temperatures are central to the understanding of drug action in living systems [4].…”

Section: Introductionmentioning

confidence: 99%

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Solvation behaviour of an antihelmintic drug in aqueous solutions of sodium chloride and glucose at different temperatures

Bhattacharya

Dhondge²,

Zodape

2016

The Journal of Chemical Thermodynamics

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Section: Relative Viscositysupporting

confidence: 89%

“…The values of the standard deviation, r and average absolute deviation (AAD) for apparent molar volume of the solute have been obtained using following expressions [3],…”

Section: Resultsmentioning

confidence: 99%

Section: Viscosity Coefficientsmentioning

confidence: 99%

“…The relative viscosities (g r ) of the solutions can be related to the solute concentration (C) using Jones-Dole equation [3,18] as given:…”

Section: Viscosity Coefficientsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Solvation behaviour of an antihelmintic drug in aqueous solutions of sodium chloride and glucose at different temperatures

Bhattacharya

Dhondge²,

Zodape

2016

The Journal of Chemical Thermodynamics

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Use of Masson's and Jones–Dole equations to study different types of interactions of three pharmacologically important drugs in ethanol

Shakeel¹,

Mehmood

2020

J Chinese Chemical Soc

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The volumetric and viscometric study of three allopathic drugs (sodium valporate, benzalkonium chloride, and losartan potassium) in ethanol solvent is reported here. This study was carried out at four different temperatures that is, from 288.15 to 318.15 K. The accurately measured density values were used to calculate partial molar volume at infinite dilution, solute-solute interaction parameter, Hepler's constant, partial molar expansivity constant, and isobaric thermal expansion coefficient. The viscosity measurements were carried out

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Physicochemical studies of adenosine in the presence of aqueous caffeine and theophylline solutions, & sodium valproate with γ‐amino butyric acid in aqueous medium at T = (288.15–318.15) K and at p = 1 × 10⁵ Pa

Beri,

Kant,

Banipal

2024

Vietnam Journal of Chemistry

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In human body, drug‐neurotransmitter interactions have been the most significant process. Whereas, adverse reactions may be accompanied by unexpected interaction, which puts an individual in danger of life. Thus, the interactions between adenosine (ADN) and sodium valproate (SV) with caffeine (CAF), theophylline (TPY) and γ‐amino butyric acid (GABA) have been studied. Various properties like densities, ρ and speed of sound, u, have been used to calculate apparent molar volumes (V2,ϕ) and apparent molar isentropic compression (Ks,2,ϕ) for ADN and SV in aqueous (5, 10, 15 and 20 mmol kg−1) CAF, TPY and GABA solutions at T = (288.15–318.15) K and at pressure p = 1 × 105 Pa. The results of various interactions that occurred by mixing the solutions have been interpreted. Exothermicity is indicated by the negative values of standard molar enthalpy of transfer, ΔtrΔdilH0, obtained from the calorimetry. UV‐absorption and 1H NMR studies suggest that there is a dominance of solute‐cosolute interactions due to hyperchromic shift and shielding effect.

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Physicochemical properties of an anticonvulsant drug sodium valproate in aqueous and in mixed aqueous solutions at different temperatures

Cited by 46 publications

References 54 publications

Solvation behaviour of an antihelmintic drug in aqueous solutions of sodium chloride and glucose at different temperatures

Solvation behaviour of an antihelmintic drug in aqueous solutions of sodium chloride and glucose at different temperatures

Use of Masson's and Jones–Dole equations to study different types of interactions of three pharmacologically important drugs in ethanol

Physicochemical studies of adenosine in the presence of aqueous caffeine and theophylline solutions, & sodium valproate with γ‐amino butyric acid in aqueous medium at T = (288.15–318.15) K and at p = 1 × 10⁵ Pa

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Physicochemical properties of an anticonvulsant drug sodium valproate in aqueous and in mixed aqueous solutions at different temperatures

Cited by 46 publications

References 54 publications

Solvation behaviour of an antihelmintic drug in aqueous solutions of sodium chloride and glucose at different temperatures

Solvation behaviour of an antihelmintic drug in aqueous solutions of sodium chloride and glucose at different temperatures

Use of Masson's and Jones–Dole equations to study different types of interactions of three pharmacologically important drugs in ethanol

Physicochemical studies of adenosine in the presence of aqueous caffeine and theophylline solutions, & sodium valproate with γ‐amino butyric acid in aqueous medium at T = (288.15–318.15) K and at p = 1 × 105 Pa

Contact Info

Product

Resources

About

Physicochemical studies of adenosine in the presence of aqueous caffeine and theophylline solutions, & sodium valproate with γ‐amino butyric acid in aqueous medium at T = (288.15–318.15) K and at p = 1 × 10⁵ Pa