Physicochemical Properties and Biological Activities of Garden Cress (Lepidium sativum L.) Seed and Leaf Oil Extracts

Adera, Fikremariam; Yusuf, Zekeria; Desta, Mulugeta

doi:10.1155/2022/2947836

Cited by 11 publications

(10 citation statements)

References 10 publications

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“…MIC is the lowest concentration at which no colour change occurs [ 63 , 64 ], whereas MBC is the lowest concentration at which no growth is seen on a petri dish [ 65 ].…”

Section: Resultsmentioning

confidence: 99%

Silver nanoparticle biosynthesis utilizing Ocimum kilimandscharicum leaf extract and assessment of its antibacterial activity against certain chosen bacteria

Ouandaogo,

Diallo,

Odari

et al. 2024

PLoS ONE

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The use of plants in the biological production of silver nanoparticles for antibacterial applications is a growing field of research. In the current work, we formulated Ocimum kilimandscharicum extracts using silver nanoparticles, and evaluated its potential antibacterial activity. Aqueous and methanol plant extracts were used to reduce silver nitrate at different time intervals (30 to 150 minutes) and pH (2 to 11). The UV-visible absorption spectrum recorded for methanol and aqueous extracts revealed a successful synthesis of AgNPs for methanol and aqueous extracts. The antimicrobial activity of the AgNPs was evaluated against Escherichia coli ATCC 25922, Salmonella choleraesuius ATCC 10708, and Staphylococcus aureus ATCC 25923 The best inhibition zone for the methanol and aqueous-mediated AgNPs, ranging from 12 ± 1 to 16 ± 1mm. Additionally, the methanol and aqueous extract silver nanoparticles had the same Minimum Inhibitory Concentration (6.25 ± 0.00 mg/ml), whereas the Minimum Bactericidal Concentrations were 12.5 ± 0.00 and 25 ± 0.00 mg/ml, respectively. The highest inhibition zone of 16 ± 1 mm was observed against Salmonella choleraesuius with 50 ± 0.00 mg/ml aqueous silver nanoparticles. The results show that the silver nanoparticles made with Ocimum kilimandscharicum have antibacterial action against those microorganisms.

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“…MIC is the lowest concentration at which no colour change occurs [ 63 , 64 ], whereas MBC is the lowest concentration at which no growth is seen on a petri dish [ 65 ].…”

Section: Resultsmentioning

confidence: 99%

Silver nanoparticle biosynthesis utilizing Ocimum kilimandscharicum leaf extract and assessment of its antibacterial activity against certain chosen bacteria

Ouandaogo,

Diallo,

Odari

et al. 2024

PLoS ONE

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“…These essential oils’ enhanced macrophage phagocytic index may be due to their antioxidant properties. 11 , 21 The immune system is strengthened by antioxidants. 23 The stimulation of the hematological system and lymphocyte differentiation may be associated with the increased carbon clearance rate.…”

Section: Discussionmentioning

confidence: 99%

“…However, the leaf oil possesses better antibacterial activity. 20 , 21 Flavonoids, phenolics, alkaloids, saponins, glycosides, coumarins, fixed oils, proteins, vitamins, and minerals were found in L. sativum essential oil. 22 …”

Section: Introductionmentioning

confidence: 99%

In-vivo Immunomodulatory Activities of Essential Oils of Artemisia abyssinica and Lepidium sativum in Mice

Ayenew,

Ayalew,

Wondmkun

et al. 2024

ITT

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Background Ethiopians use Artemisia abyssinica and Lepidium sativum as immunity enhancers. However, there is no scientific validation conducted so far regarding this claim. The aim of this study was to investigate the in-vivo immunomodulatory activities of essential oils of A. abyssinica and L. sativum in mice. Methods The extraction was carried out using the earlier techniques. By hydro distilling fresh seeds and aerial portions of A. abyssinica and L. sativum , respectively, essential oils were obtained. Essential oils of both plants were tested at 100, 200 and 400 mg/kg. The rate of carbon clearance, humoral antibody titer, delayed type hypersensitivity response, spleen and thymus indices were evaluated in mice according to scientific protocols. The carbon clearance assay was determined using carbon ink. Sheep red blood cell was used as an antigen for other tests. Results Essential oils of A. abyssinica and L. sativum at 400 mg/kg significantly increased the rate of carbon clearance from the body of mice ( p <0.05). The maximum carbon clearance rate was achieved for A. byssinica essential oil at 400 mg/kg. Both essential oils raised the level of HAT to SRBC in comparison to the vehicle and cyclophosphamide administered groups. The largest (84.668±1.951) mean secondary HAT to SRBC was generated by L. sativum essential oil at 400 mg/kg ( p <0.001). A. abyssinica essential oil at 200 and 400 mg/kg significantly increased the level of thymus index compared to the model group ( p <0.05 and 0.01 respectively). The levamisole group experienced the highest increase in thymus index ( p <0.001). Essential oil of L. sativum at 400 mg/kg also increased the level of thymus index. The spleen index in mice was improved by the essential oils only at the highest dose levels (400 mg/kg). Conclusion It can be inferred that the essential oils of L. sativum and A. abyssinica have immunostimulant properties.

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“…The oil yield and specific gravity were done based on Soxhlet oil method [ 13 – 15 ]. The percentage oil yield of each sample was determined as follows:

where oil weight = W2-W1, W1 is the weight of the extraction flask (g), and W2 is the weight of the extraction flask plus the dried crude fat (g).…”

Section: Methodsmentioning

confidence: 99%

Physicochemical Properties and Biological Activities of Garlic (Allium sativum L.) Bulb and Leek (Allium ampeloprasum L. var. Porrum) Leaf Oil Extracts

Lemma

Yusuf

Desta

et al. 2022

The Scientific World Journal

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Allium species including garlic and leek exhibits a broad range of medicinal and nutritional properties. Therefore, this study investigates the physicochemical and biological activities of garlic (Allium sativum L.) and leek (A. ampeloprasum L. var. Porrum) oil extracts. The result indicated that physicochemical properties indicated that significantly higher oil yield (21.25%), ACV (2.66 mg/g), FFA (1.34%), and PV (4.10 meq/kg) and also antioxidant activities with respect to 2, 2-diphenyl-1-picrylhydrazyl, DPPH (27.60 ± 1.55%), hydrogen peroxide (12.35 ± 0.92%) free radical scavenging activities, and ascorbic acid content (25.30 ± 3.25%) were obtained for leek leaf oil extract. Stronger antibacterial activity with a maximum zone of inhibition (16.00 mm), minimum inhibitory concentration (MIC) (0.20 µg/ml), and minimum bactericidal concentration (MBC) (0.40 µg/ml) was recorded for leek oil extract against S. pyogenes. However, garlic oil has presented stronger antifungal activity with a maximum zone of inhibition (13.50 mm), MIC (0.40 µg/ml), and minimum fungicidal concentration (MFC) (0.75 µg/ml) against Candida albicans. It is concluded from the results of this investigation that oils extracts of garlic bulb and leek leaves demonstrated significant biological activities that can be used as sources for pharmaceutical and nutraceutical ingredients.

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Physicochemical Properties and Biological Activities of Garden Cress (Lepidium sativum L.) Seed and Leaf Oil Extracts

Cited by 11 publications

References 10 publications

Silver nanoparticle biosynthesis utilizing Ocimum kilimandscharicum leaf extract and assessment of its antibacterial activity against certain chosen bacteria

Silver nanoparticle biosynthesis utilizing Ocimum kilimandscharicum leaf extract and assessment of its antibacterial activity against certain chosen bacteria

In-vivo Immunomodulatory Activities of Essential Oils of Artemisia abyssinica and Lepidium sativum in Mice

Physicochemical Properties and Biological Activities of Garlic (Allium sativum L.) Bulb and Leek (Allium ampeloprasum L. var. Porrum) Leaf Oil Extracts

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