Physicochemical investigations of zinc oxide nanoparticles synthesized from Azadirachta Indica (Neem) leaf extract and their interaction with Calf-Thymus DNA

Singh, Amit; Neelam, .; Kaushik, Mahima

doi:10.1016/j.rinp.2019.102168

Cited by 55 publications

(26 citation statements)

References 33 publications

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“…Many parts of plants such as leaf, fruit, stem, bark, root, leaf, and bud have been utilized for the green synthesis of Ag nanoparticles. Many plant products such as Azadirachta indica (Neem) leaf extract [38,44,45]. Tribulus longipetalus extract [40], Acacia nilotica pods [46], Ficus altissima Blume leaf extract [47], and aqueous leaf extracts of Emblica officinalis [42], are capable of reducing metal ions to nanoparticles because of their antioxidant properties.…”

Section: Introductionmentioning

confidence: 99%

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Green Synthesis of an Activated Carbon-Supported Ag and ZnO Nanocomposite for Photocatalytic Degradation and Its Antibacterial Activities

2020

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In this study Ag nanoparticles (AgNPs), ZnO nanoparticles (ZnONPs), and Ag/ZnO nanocomposites were greenly synthesized and loaded on activated carbon via three different routes: simple impregnation, successive precipitation, and co-precipitation. Neem leaf extract was used as a reducing and stabilizing agent. The morphological and structural properties of the synthesized nanocomposites have been examined using different analytical techniques such as XRD, SEM, FTIR, and UV. The antibacterial and catalytic activity of the synthesized nanocomposites were examined and compared. The results showed that AgNPs loaded on activated carbon (Ag/AC) has the best catalytic activity compared to the other nanocomposites, which is attributed to the good dispersal of AgNPs on the surface of activated carbon. Furthermore, AgNPs showed the best antibacterial effect on eight out of 16 tested pathogens. Results also showed that the order of precipitation is an important factor, as both antibacterial activities and photodegradation activities were higher for ZnO/Ag/AC than Ag/ZnO/AC. Furthermore, the co-precipitation method was shown to be better than the successive precipitation method for 4-nitrophenol photodegradation and 14 out of the 16 antibacterial tests performed.

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Section: Introductionmentioning

confidence: 99%

“…Furthermore, it contains two important classes of chemicals, namely terpenoids and flavanones. These compounds act as reducing as well as a capping agents to stabilize nanoparticles [45,48,49].…”

Section: Introductionmentioning

confidence: 99%

Green Synthesis of an Activated Carbon-Supported Ag and ZnO Nanocomposite for Photocatalytic Degradation and Its Antibacterial Activities

2020

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“…This fluorescence enhancement suggested electrostatic interaction between DNA and NiO NPs. This interaction is the opposite of quenching, in which small ligands replace the intercalated AO molecules and thereby cause a reduction in intensity.…”

Section: Resultsmentioning

confidence: 99%

Green synthesis and physiochemical characterization of nickel oxide nanoparticles: Interaction studies with Calf thymus DNA

2019

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One of the most promising applications of nanomaterials is that of nanobiosensors, using biomolecules such as nucleic acids as receptors. This study aimed to synthesize nickel oxide nanoparticles (NiO NPs) by an environmentally friendly green synthesis, using the extract of the herb Coriandrum sativum (coriander). The synthesized NPs were characterized using UV–Visible spectroscopy, Fourier transform infrared spectroscopy, X‐ray diffraction, X‐ray photon spectroscopy, field emission scanning electron microscopy coupled with energy dispersive spectroscopy, dynamic light scattering, zeta potential and transmission electron microscopy. All results confirmed the synthesis of pure, spherical, positively charged NiO NPs of around 95 nm in diameter with prominent hydroxyl groups attached to the surface. Furthermore, interaction studies of synthesized NiO NPs with calf thymus DNA (CT DNA) were performed using UV–Visible spectroscopy, UV–thermal melting, circular dichroism, and fluorescence spectroscopy. CT DNA served as a substitute for nucleic acid biosensors. All experimental studies indicated that the NiO NPs bound electrostatically with CT DNA. These studies may facilitate exploring the potential of NiO NP–nucleic acid conjugated materials to be used as nanobiosensors for various applications, especially in pharmacological, epidemiological, and environmental diagnostic applications, and in detection.

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“…Very light signals between 2300 cm -1 and 2400 cm -1 are also indications of C=C bonds. The signals within 3500 cm -1 and 4000cm -1 are due to vibrations of C-H or O-H bonds which participate in bioreduction reaction [38] .The stability of ZnO NPs may be due to amino group and carboxylic group [39] . Fig.…”

Section: Spore Germination Inhibition Assaymentioning

confidence: 99%

Green Synthesis of Cu2+ doped ZnO nanoparticles to investigate their Structural, Optical, Morphological properties and Antifungal activities

2020

JCBSC

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Recently ZnO nanoparticle has become the limelight between different kinds of metal nanoparticles because of its different kinds of applications. Doping on ZnO nanoparticles improves its physiochemical properties for designing new funtionalities. This aspect prompted us to investigate the green synthesis of pure and Cu-doped ZnO nanoparticles using Azadirachta Indica (Neem) leaf extract for structural, optical, morphological properties and antifungal applications. The synthesized materials were characterized by Scanning Electron Microscope (SEM), UV-vis spectroscopy, X-ray diffraction study (XRD), Dynamic light scattering (DLS) studies, Fourier transforms infra-red spectroscopy (FTIR). From XRD pattern the crystalline sizes of pure and Cu-doped nanoparticles were measured. The band gap of pure and Cu-doped ZnO samples was calculated from UV-Vis absorption and Tauc plots. Further it is fascinating to note the abrupt increase of band gap when Cu 2+ ion is doped in ZnO. The values of Band gap energy of pure ZnO was found to be 3.31eV and for the doped materials, it is found to be in the range of 5.37 to 5.41 eV. The Antifungal activities of characterized samples were determined against major harmful fungi Rhizopus. Green Synthesis… Debasmita Das et al.

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Physicochemical investigations of zinc oxide nanoparticles synthesized from Azadirachta Indica (Neem) leaf extract and their interaction with Calf-Thymus DNA

Cited by 55 publications

References 33 publications

Green Synthesis of an Activated Carbon-Supported Ag and ZnO Nanocomposite for Photocatalytic Degradation and Its Antibacterial Activities

Green Synthesis of an Activated Carbon-Supported Ag and ZnO Nanocomposite for Photocatalytic Degradation and Its Antibacterial Activities

Green synthesis and physiochemical characterization of nickel oxide nanoparticles: Interaction studies with Calf thymus DNA

Green Synthesis of Cu2+ doped ZnO nanoparticles to investigate their Structural, Optical, Morphological properties and Antifungal activities

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