Physicochemical and functional properties of a protein isolate from maca (Lepidium meyenii) and the secondary structure and immunomodulatory activity of its major protein component

Abstract

Introduction of the maca protein and its physicochemical and functional properties, structure and immunomodulatory activity.

Structural, physicochemical and functional properties of Semen Ziziphi Spinosae protein

“…The sulydryl groups and disulde bonds were determined according to a report by Wu et al with some modications. 21 To determine the SH, SZSP (30 mg) was dissolved in 10 mL Tris-Gly-8 M urea buffer, and then 50 mL Ellman reagent (DNTB, 4 mg mL À1 ) was added. The protein suspension was incubated at 25 C for 60 min and then centrifuged at 5000g for 10 min.…”

Aplicações Terapêuticas Da Lepidium Meyenii (Maca) E Seus Compostos Químicos: Uma Revisão Sistemática / Therapeutic Applications of Lepidium Meyenii (Maca) and Its Chemical Compounds: A Systematic Review

“…A maca consegue ainda estimular o sistema imunológico a partir do estímulo de aumento da fagocitose e produção de NO, TNF-α e IL-6, como revelado por Wu et al (2019) ao testar um composto protéico da maca. Zha et al (2018) apresentaram que um polissacarídeo composto por arabnose e glicose exerceram ação imunoestimulante em células RAW264.7 ao aumentar a sua viabilidade, expressão de receptores TLR4 e TLR2 e citocinas TNF-a, IL-1β e IL-6.…”

“…Sua raiz é considerada um alimento de alto valor nutricional, semelhante aos grãos de cereais, possui carboidratos (59-73%), proteínas (10-18%), fibras (8,5%) e conteúdo mineral. A parte comestível da maca são os hipocótilos e a raiz (WU et al, 2019).…”

Lepithiohydimerins A—D: Four Pairs of Neuroprotective Thiohydantoin Dimers Bearing a Disulfide Bond from Maca (Lepidium meyenii Walp.)

“…[1‐2] Tubers of Maca is main nutritional part due to a variety of dietary constituents, such as starch, fiber, and protein. [ 3‐4 ] In addition, amounts of functional compounds ( e.g ., flavonoids, macamides, macaenes, glucosinolates, and macahydantoins) have been found from the tubers, and showed antifatigue, antioxidant, anti‐cancer, energy metabolism regulation, neuroprotective, and immunomodulatory activities. [ 5‐10 ]…”