Physico-chemical characterization and cytotoxicity evaluation of curcumin loaded in chitosan/chondroitin sulfate nanoparticles

Curcumin nanoparticles loaded hydrogels protects against aflatoxin B1-induced genotoxicity in rat liver

“…The health beneficial properties of Cur included the antiinflammatory, antitumor, antioxidant, antimicrobial and others (Menon and Sudheer, 2007;Surh and Chun, 2007;Gota et al, 2010;Ismaiel et al, 2015). However, the therapeutic use of Cur has been limited due to its low solubility in aqueous solutions and its high decomposition rate at neutral or basic pH as well as its susceptibility to photochemical degradation (Jardim et al, 2015). To overcome these problems, several ways had been explored such as the nano-system and pro-drug strategies which attracted much attention (Onoue et al, 2010;Jardim et al, 2015).…”

“…However, the therapeutic use of Cur has been limited due to its low solubility in aqueous solutions and its high decomposition rate at neutral or basic pH as well as its susceptibility to photochemical degradation (Jardim et al, 2015). To overcome these problems, several ways had been explored such as the nano-system and pro-drug strategies which attracted much attention (Onoue et al, 2010;Jardim et al, 2015). The aims of the current study were to synthesized and characterized Cur nano particles loaded hydrogel and to evaluate its protective role against AFB 1 -induce damage, genotoxicity and apoptosis in rat liver.…”

Efficacy and Safety of 3 Nasal Packing Materials Used After Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: A Comparative Study in China

“…The unique open grid services architecture of CMC allows it to impose negative pressure on wounds and thereby promote cell division and regeneration of the wounds. The Aquacel1-Ag wound dressing is capable of providing silver ions with antimicrobial activity to create a clean environment that promotes wound healing [19]. Compared to the other materials, Aquacel1-Ag shortens recovery times and thereby reduces the financial and emotional burdens on patients [7].…”

Encapsulation of mesenchymal stem cells in glycosaminoglycans‐chitosan polyelectrolyte microcapsules using electrospraying technique: Investigating capsule morphology and cell viability

“…In dilute acidic solution, chitosan amino groups protonate and the polymer can subsequently form ionic complexes with a wide variety of natural or synthetic anionic species . Other specific characteristics of the chitosan include: antibacterial, antifungal, mucoadhesive, analgesic, and haemostatic properties . GAGs are also a family of highly sulfated, complex polysaccharides that play a variety of important biological roles in the body.…”

“…25 Other specific characteristics of the chitosan include: antibacterial, antifungal, mucoadhesive, analgesic, and haemostatic properties. 26 GAGs are also a family of highly sulfated, complex polysaccharides that play a variety of important biological roles in the body. All GAGs are negatively charged due to the presence of carboxyl and/or acidic sulphate groups.…”