Physico-chemical and mechanical characterization of hydrogels of poly (vinyl alcohol) and hyaluronic acid

Lazzeri, Luigi; Barbani, Niccoletta; Cascone, Maria Grazia; Lupinacci, Domenico; Giusti, P.; Laus, Michele

doi:10.1007/bf01172026

Cited by 24 publications

(24 citation statements)

References 1 publication

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“…In this fashion, the biopolymer molecules modify the thermal, rheological, and mechanical properties of the pristine synthetic polymer. Similar effects are reported in literature for blends made from polyvinyl alcohol (PVA) and natural materials such as PVA/algae, 18 PVA/corn fiber, 2 PVA/hyaluronic acid, 19 PVA/sugar cane bagasse. 3 It has been found in the present work that the biopolymers increase the yield strength of the synthetic polymer if present at low concentration (less than 10%).…”

Section: Discussionsupporting

confidence: 78%

“…17 As observed for the thermal properties, F2 blends resulted in a significant change of mechanical properties. This trend has been reported also for other blends containing polyvinyl alcohol (PVA) such as PVA/algae, 18 PVA/corn fiber, 2 PVA/hyaluronic acid, 19,20 PVA/sugar cane bagasse. 3 In essence, upon increasing F2 concentration in the film, the Young's modulus increases to an average 610 MPa value and the strain at break decreases from 86% in neat EVOH to 35 to 10% across the 10 samples fabricated at 0.1 to 1.0 F2/EVOH weight ratio.…”

Section: Films Thermal and Mechanical Behaviormentioning

confidence: 67%

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Films made from poly(vinyl alcohol‐co‐ethylene) and soluble biopolymers isolated from postharvest tomato plant

Franzoso

Antonioli

Montoneri

et al. 2015

J of Applied Polymer Sci

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Blended films were obtained from polyvinyl alcohol-co-ethylene (EVOH) with 52 kDa weight average molecular weight (M w ) and three water soluble biopolymers isolated from exhausted tomato plants hydrolysates. Two biopolymers contained mainly polysaccharides and had 27 and 79 kDa M w , respectively. The third contained mainly lignin-like C moieties and had 392 kDa M W . The films were fabricated with a biopolymer/EVOH w/w ratio ranging from 0.1 to 0.9. All blends had molecular weight and solubility which were substantially different from the starting materials. They were characterized for the chemical nature, and the thermal, rheological, and mechanical properties. Evidence of a chemical reaction between the biopolymers and EVOH was found. Generally, the films exhibited higher mechanical strength but lower strain at break then the neat EVOH. The best performing blended film was fabricated from the 27 kDa M w polysaccharide. This contained less than 10% biopolymer. It exhibited 1043 MPa Young's modulus and 70% strain at break against 351 MPa modulus and 86% strain for neat EVOH. The results offer scope for investigating biopolymers sourced from other biowastes to understand more the reasons of the observed effects and exploit their full potential to modify or to replace synthetic polymers.

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Section: Discussionsupporting

confidence: 78%

Section: Films Thermal and Mechanical Behaviormentioning

confidence: 67%

Films made from poly(vinyl alcohol‐co‐ethylene) and soluble biopolymers isolated from postharvest tomato plant

Franzoso

Antonioli

Montoneri

et al. 2015

J of Applied Polymer Sci

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“…Similar effects are reported in the literature for blends made from PVA and natural materials, such as algae, 28 corn fiber, 5 hyaluronic acid, 29,30 and sugar cane bagasse. 6 We determined in this study that the SBOs increased the yield strength of the synthetic polymer when present at low concentrations (ca.…”

Section: Film Mechanical Behaviorsupporting

confidence: 83%

Films made from poly(vinyl alcohol‐co‐ethylene) and soluble biopolymers isolated from municipal biowaste

Franzoso

Tabasso

Antonioli

et al. 2014

J of Applied Polymer Sci

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Blends were obtained from poly(vinyl alcohol-co-ethylene) and water-soluble biopolymers isolated from the alkaline hydrolysate of two materials sampled from an urban waste treatment plant: that is, an anaerobic fermentation digestate and a compost. The digestate biopolymers contained more lipophilic and aliphatic C and less acidic functional groups than the compost biopolymers. Evidence was obtained for a condensation reaction occurring between the biopolymers and the synthetic polymer. The thermal, rheological, and mechanical properties of the blends were studied. Films containing a low concentration (ca. 6-7%) of biopolymers exhibited up to three times higher yield strength than the neat synthetic polymer. The films' properties were found to be dependent on the concentration and nature of the biopolymers. The results offer a scope for investigating biopolymers sourced from other biowastes and for a better understanding of the reasons for the observed effects and exploiting their full potential for modifying or replacing synthetic polymers.

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“…It has been reported that high water content PVA-H has selective permeability penetrating into low molecular weight nutrients such as glucose and protein, but not substances with cell-size levels such as fibroblasts and leukocytes [114,115]. In addition, the gel prevents adhesion on the surface by preventing cell viability.…”

Section: Tendon Tissue Engineeringmentioning

confidence: 99%

“…We note that polyvinyl alcohol hydrogel (PVA-H) has a high water content with both adhesion-inhibiting function and synovial perfusion function. PVA-H has been extensively studied as a biomaterial [113,114], and mechanical strength and biocompatibility have been excellent.…”

Section: Tendon Tissue Engineeringmentioning

confidence: 99%

Hydrogels in Regenerative Medicine

Budama‐Kilinc¹,

Çakır-Koç²,

Aslan³

et al. 2018

Biomaterials in Regenerative Medicine

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Polymer scaffolds have many various applications in the field of tissue engineering, drug delivery, and implantation. They are applied as dispensing devices for bioactive molecules and as three-dimensional (3D) structures that provide stimulants that organize cells and direct desired original tissue formation. Hydrogels are preferred scaffolding material because they are structurally similar to the extracellular matrix of many tissues, often processed under mild conditions, and can be delivered in a minimally invasive manner. Hydrogel materials formed a group of polymeric materials. The hydrophilic structure allows them to hold large amounts of water in their three-dimensional backbone. As a result, hydrogels are used as scaffolding material for drug and growth factor transmission, tissue engineering modifications, and many other applications. In this chapter, we describe the physical and chemical structure of hydrogels, side groups, cross-linkings, swelling properties, types of polymers and fabrication methods, and application fields.

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Physico-chemical and mechanical characterization of hydrogels of poly (vinyl alcohol) and hyaluronic acid

Cited by 24 publications

References 1 publication

Films made from poly(vinyl alcohol‐co‐ethylene) and soluble biopolymers isolated from postharvest tomato plant

Films made from poly(vinyl alcohol‐co‐ethylene) and soluble biopolymers isolated from postharvest tomato plant

Films made from poly(vinyl alcohol‐co‐ethylene) and soluble biopolymers isolated from municipal biowaste

Hydrogels in Regenerative Medicine

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