Physical Performance Test and Karnofsky Performance Status are unable to identify elderly cancer patients requiring a Comprehensive Geriatric Assessment

Ghosn, Marwan; Nassani, Najib; Ghanem, Sassine; Ibrahim, Tony

doi:10.1016/j.eurger.2015.05.008

Cited by 8 publications

(20 citation statements)

References 41 publications

(74 reference statements)

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“…Recently, Augschoell et al [17] evaluated PPT as a screening tool in 77 patients, and showed that this test had a prognostic impact on survival. However, the present authors found that although KPS and PPT were statistically correlated, neither of them predicted OS [22]. It should be noted that KPS only had a prognostic impact in patients who had longer OS (N120 days).…”

Section: Discussionmentioning

confidence: 48%

“…Patient characteristics and results for each score have been published previously [22]. This study enrolled 120 patients of whom 14 patients were excluded (six had KPS score b60 and eight had MMSE score b23).…”

Section: Resultsmentioning

confidence: 99%

“…This study found that abridged GA, although time consuming (median time for completion 48 min) [22], was the only tool to predict survival in elderly cancer patients, especially for visual and hearing impairments.…”

Section: Discussionmentioning

confidence: 97%

“…Inclusion and exclusion criteria have been reported previously [22]. In brief, included subjects had to be aged N70 years with a KPS score ≥60 and a Mini-Mental State Examination (MMSE) score ≥ 23.…”

Section: Methodsmentioning

confidence: 99%

“…According to some authors, these can predict treatment outcome, OS and quality of life [17][18][19][20][21]. A previous report showed that both KPS and PPT were negatively correlated with abridged GA, but were not efficient screening tests for unfit patients [22]. The aim of this study was to evaluate and compare the predictive values of KPS, PPT and abridged GA for mortality in elderly cancer patients.…”

Section: Introductionmentioning

confidence: 98%

See 4 more Smart Citations

Abridged geriatric assessment is a better predictor of overall survival than the Karnofsky Performance Scale and Physical Performance Test in elderly patients with cancer

Ghosn

Ibrahim

Rassy

et al. 2017

Journal of Geriatric Oncology

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Section: Discussionmentioning

confidence: 48%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 97%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

See 3 more Smart Citations

Abridged geriatric assessment is a better predictor of overall survival than the Karnofsky Performance Scale and Physical Performance Test in elderly patients with cancer

Ghosn

Ibrahim

Rassy

et al. 2017

Journal of Geriatric Oncology

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Association of Oncologist-Patient Communication With Functional Status and Physical Performance in Older Adults

Jensen-Battaglia

Lei

et al. 2022

JAMA Netw Open

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IMPORTANCEThe functional status and physical performance of older adults with cancer are underassessed and undertreated despite the high prevalence of impaired functional status and physical performance in this population and their associations with chemotherapy-induced toxic effects and mortality. OBJECTIVE To examine the association between providing oncologists with a geriatric assessment (GA) summary with recommendations and having oncologist-patient conversations about functional and physical performance.

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Screening Tools for Identifying Older Adults With Cancer Who May Benefit From a Geriatric Assessment

et al. 2021

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IMPORTANCEOlder adults with cancer are at risk of overtreatment or undertreatment when decision-making is based solely on chronological age. Although a geriatric assessment is recommended to inform care, the time and expertise required limit its feasibility for all patients. Screening tools offer the potential to identify those who will benefit most from a geriatric assessment. Consensus about the optimal tool to use is lacking.OBJECTIVE To appraise the evidence on screening tools used for older adults with cancer and identify an optimal screening tool for older adults with cancer who may benefit from geriatric assessment.EVIDENCE REVIEW Systematic review of 4 databases (MEDLINE, Embase, CINAHL [Cumulative Index to Nursing and Allied Health Literature], and PubMed) with narrative synthesis from January 1, 2000, to March 14, 2019. Studies reporting on the diagnostic accuracy and use of validated screening tools to identify older adults with cancer who need a geriatric assessment were eligible for inclusion. Data were analyzed from March 14, 2019, to March 23, 2020.FINDINGS Seventeen unique studies were included, reporting on the use of 12 screening tools. Most studies were prospective cohort studies (n = 11) with only 1 randomized clinical trial. Not all studies reported time taken to administer the screening tools. The Geriatric-8 (G8) (n = 12) and the Vulnerable Elders Survey-13 (VES-13) (n = 9) were the most frequently evaluated screening tools. The G8 scored better in sensitivity and the VES-13 in specificity. Other screening tools evaluated include the Groningen Frailty Index, abbreviated comprehensive geriatric assessment, and Physical Performance Test in 2 studies each. All other screening tools were evaluated in 1 study each. CONCLUSIONS AND RELEVANCETo date, the G8 and VES-13 have the most evidence to recommend their use to inform the need for geriatric assessment. When choosing a screening tool, clinicians will need to weigh the tradeoffs between sensitivity and specificity. Future research needs to further validate or improve current screening tools and explore other factors that can influence their use, such as ease of use and resourcing.

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Physical Performance Test and Karnofsky Performance Status are unable to identify elderly cancer patients requiring a Comprehensive Geriatric Assessment

Cited by 8 publications

References 41 publications

Abridged geriatric assessment is a better predictor of overall survival than the Karnofsky Performance Scale and Physical Performance Test in elderly patients with cancer

Abridged geriatric assessment is a better predictor of overall survival than the Karnofsky Performance Scale and Physical Performance Test in elderly patients with cancer

Association of Oncologist-Patient Communication With Functional Status and Physical Performance in Older Adults

Screening Tools for Identifying Older Adults With Cancer Who May Benefit From a Geriatric Assessment

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