Background; Studies of the maximal oxygen uptake (VO2max) of transfemoral amputees (TFA) have mostly used protocols that activate a relatively small muscle mass. Consequently, TFA VO2max may be systematically underestimated, and the validity of these test protocols is questionable.Objectives; 1) Investigate validity and reliability of a VO2max walking protocol. 2) Compare the VO2max of a TFA group to a group of matching controls (CON).Study design; 1) Randomized crossover study; walking vs. running VO2max for the CON group, 2) case-control study; TFA vs. CON group VO2max.Methods; Twelve TFA and CON participants performed a walking VO2max test with increasing treadmill inclinations to voluntary exhaustion. The CON group also completed a running ("gold-standard") VO2max test.Results; Mean (SD) CON group VO2max following walking and running was similar, i.e. 2.99 (0.6) and 3.09 (0.7) L·min -1 , respectively. Mean (SD) TFA walking VO2max was 2.14 (0.8) L·min -1 (compared to CON; p < 0.01). Mean intra-class correlation coefficient (ICC) of repeated VO2 measurements was 0.97, and within-subjects standard deviation (Sw) was 60 mL min -1 .
Conclusions;The walk protocol is valid. Walking VO2max of TFA was 40 % lower compared to CON.Reliability of the walking protocol is comparable to other walking protocols.
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Clinical relevanceThe design, alignment and materials of prostheses are important for effective ambulation. Cardiorespiratory fitness is, however, also important in this regard, and a low fitness may compromise health and independent living. Hence, TFA with low physical fitness should engage in regular physical activity to improve health, gait capacity and independency.Word count: 50