Physical Activity, Sedentary Behavior, and Melatonin Among Rotating Shift Nurses

McPherson, Mark; Janssen, Ian; Grundy, Anne; Tranmer, Joan; Richardson, Harriet; Aronson, Kristan J.

doi:10.1097/jom.0b013e31822282fd

Cited by 16 publications

(10 citation statements)

References 28 publications

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“…Apart from this, the present study is the first to show that maternal melatonin has long-term effects in offspring by modulating glucose homeostasis. The present data are of particular importance because life-style and working schedules associated with disruptions in melatonin secretion are highly prevalent in developed countries [1], [29], [30].…”

Section: Discussionmentioning

confidence: 88%

Maternal Melatonin Programs the Daily Pattern of Energy Metabolism in Adult Offspring

et al. 2012

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BackgroundShift work was recently described as a factor that increases the risk of Type 2 diabetes mellitus. In addition, rats born to mothers subjected to a phase shift throughout pregnancy are glucose intolerant. However, the mechanism by which a phase shift transmits metabolic information to the offspring has not been determined. Among several endocrine secretions, phase shifts in the light/dark cycle were described as altering the circadian profile of melatonin production by the pineal gland. The present study addresses the importance of maternal melatonin for the metabolic programming of the offspring.Methodology/Principal FindingsFemale Wistar rats were submitted to SHAM surgery or pinealectomy (PINX). The PINX rats were divided into two groups and received either melatonin (PM) or vehicle. The SHAM, the PINX vehicle and the PM females were housed with male Wistar rats. Rats were allowed to mate and after weaning, the male and female offspring were subjected to a glucose tolerance test (GTT), a pyruvate tolerance test (PTT) and an insulin tolerance test (ITT). Pancreatic islets were isolated for insulin secretion, and insulin signaling was assessed in the liver and in the skeletal muscle by western blots. We found that male and female rats born to PINX mothers display glucose intolerance at the end of the light phase of the light/dark cycle, but not at the beginning. We further demonstrate that impaired glucose-stimulated insulin secretion and hepatic insulin resistance are mechanisms that may contribute to glucose intolerance in the offspring of PINX mothers. The metabolic programming described here occurs due to an absence of maternal melatonin because the offspring born to PINX mothers treated with melatonin were not glucose intolerant.Conclusions/SignificanceThe present results support the novel concept that maternal melatonin is responsible for the programming of the daily pattern of energy metabolism in their offspring.

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Section: Discussionmentioning

confidence: 88%

Maternal Melatonin Programs the Daily Pattern of Energy Metabolism in Adult Offspring

et al. 2012

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“…Authors contended that physical activity was beneficial for obstructive sleep apnea, depressive symptoms, and restless leg syndrome, all of which affect insomnia and sleep quality. Melatonin levels decreased with increased time in sedentary behaviors among nurses, which is a potential mechanism of association between sedentary behavior and sleep problems (McPherson et al, ).…”

Section: Discussionmentioning

confidence: 99%

Behavioral Characteristics and Cardiovascular Disease Risks Associated With Insomnia and Sleep Quality Among Middle‐Aged Women in South Korea

Ham

Kim

Lee

et al. 2017

Research in Nursing & Health

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Insomnia is the most common sleep problem in women. Increasing evidence suggests an association between insomnia and cardiovascular disease (CVD). However, information is limited on lifestyle and socio-environmental factors associated with sleep problems in women. In this study directed by Social Cognitive Theory, we examined the personal, behavioral, socio-environmental, and CVD risk factors associated with sleep characteristics (insomnia and sleep quality) in middle-aged women using a cross-sectional design. The study instruments included the Insomnia Severity Index (ISI), the Pittsburg Sleep Quality Index (PSQI), the Center for Epidemiological Studies Depression Scale (CES-D), and measures of social support and behavioral characteristics. Blood was drawn to assess serum glucose and lipids, and BMI was measured. Data were analyzed using hierarchical multiple regression and analysis of covariance (ANCOVA). Of 423 middle-aged women, 25% experienced insomnia (ISI ≥ 10) and 41.3% reported poor sleep quality (PSQI ≥ 5). Lesser education (≤middle school), more depressive symptoms, more screen time (≥ 3 hours/day), and severe stress were associated with greater severity of insomnia and/or poorer sleep quality. Total and LDL cholesterol levels were higher in women with insomnia than normal sleepers, whereas the BMI was higher in those who reported poor sleep quality. Because personal, behavioral, and socio-environmental factors were significantly associated with insomnia and poor sleep quality, multifactorial approaches should be considered in developing sleep interventions and reducing cardiovascular risk. © 2017 Wiley Periodicals, Inc.

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“…35,36 Beyond insufficient or poor-quality sleep, shift work disrupts the timing of many biological rhythms through being awake and/or exposed to light at night. [37][38][39] In turn, this creates discord within the individual's circadian timing system. Physiological systems are maintained in synchrony with the prevailing solar day via retinal light perception and transfer of the information to the suprachiasmatic nucleus (SCN) in the hypothalamus.…”

Section: Mechanisms Through Which Night Shift Work May Affect Fertilimentioning

confidence: 99%

Fixed or Rotating Night Shift Work Undertaken by Women: Implications for Fertility and Miscarriage

et al. 2016

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This review summarizes the evidence concerning effects of night shift work on women's reproductive health, specifically difficulty in conceiving and miscarriage. We distinguish between fixed night shift and rotating night shift, as the population subgroups exposed, the social and biological mechanisms, and the magnitude of effects are likely to differ; of note, women working fixed night shift are known to have high tolerance for this schedule. We identified two relevant systematic reviews with meta-analyses and five additional studies. Night shift work may give rise to menstrual cycle disturbances, but effect sizes are imprecise. Endometriosis may be elevated in night shift workers, but evidence is only preliminary. Adequate data are lacking to assess associations between night shift work and infertility or time to pregnancy. The weight of evidence begins to point to working at night, whether in fixed or rotating shifts, as a risk factor for miscarriage. There are many methodological problems with this literature, with substantial variation in the definitions of night shift and schedule types making comparisons between studies difficult and pooling across studies questionable. Nevertheless, there appears to be grounds for caution and counselling where women have concerns about night shift work and their reproductive health.

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Physical Activity, Sedentary Behavior, and Melatonin Among Rotating Shift Nurses

Cited by 16 publications

References 28 publications

Maternal Melatonin Programs the Daily Pattern of Energy Metabolism in Adult Offspring

Maternal Melatonin Programs the Daily Pattern of Energy Metabolism in Adult Offspring

Behavioral Characteristics and Cardiovascular Disease Risks Associated With Insomnia and Sleep Quality Among Middle‐Aged Women in South Korea

Fixed or Rotating Night Shift Work Undertaken by Women: Implications for Fertility and Miscarriage

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