Physical activity interventions for disease-related physical and mental health during and following treatment in people with non-advanced colorectal cancer

McGettigan, Maresa; Cardwell, Chris R; Cantwell, Marie; Tully, Mark A.

doi:10.1002/14651858.cd012864.pub2

Cited by 37 publications

(22 citation statements)

References 194 publications

(30 reference statements)

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“…Four systematic reviews assessed the effectiveness of exercise in CRC patients after treatment, 51–54 commonly with supervised or home‐based self‐directed delivery during a 6–12‐week period, and found consistent positive effects on short‐term physical fitness 52,53 and fatigue 51,52 . One systematic review also found evidence of positive effects on health‐related QOL at immediate‐term follow‐up 52 . And the others demonstrated that exercise could improve cardiopulmonary fitness, metabolism, and tumour‐related biomarkers for CRC survivors post‐treatment 54 .…”

Section: Resultsmentioning

confidence: 99%

“…These studies reported on a range of intervention types, according to their different intervention focus, which could be classified into CRC surveillance programme, 31,32 education (colostomy education, 33–37 psychosexual education, 38 psychoeducation, 39,40 healthy lifestyle education 41 ), psychosocial support, 42,43 supportive expression, 44,45 cognitive behavioural stress management (CBSM), 46 supportive care, 47–50 physical activity (PA) and/or dietary, 51–58 and survivorship care plan (SCP) 59,60 interventions. Detailed definitions of the interventions included are described in Table S1.…”

Section: Resultsmentioning

confidence: 99%

“…The studies that were included reported on various delivery formats, including face‐to‐face (one‐on‐one or in a group), 33–35,39–41,45,46,60 telephone, 36,38,42,48–50,56 web‐based, 58 and multiple combination with the following formats: face‐to‐face, telephone, home visit, home‐based, or web‐based 37,43,44,47,51–55,57,59 . These interventions were delivered by a range of health professionals, for example, nurse, therapist, doctor, oncologist, dietitian, psychologist, social worker, or trained research assistant.…”

Section: Resultsmentioning

confidence: 99%

“…One systematic review, which included five RCTs, found that patients undertaking home‐based exercise or supervised exercise sessions showed improvements in fatigue after the intervention, although it failed to demonstrate a significant effect 51 . Another Cochrane systematic review found evidence of positive effects of PA on cancer‐related fatigue in the short term 52 . In addition, psychosocial interventions also showed positive effects on survivors' fatigue.…”

Section: Resultsmentioning

confidence: 99%

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A literature review of post‐treatment survivorship interventions for colorectal cancer survivors and/or their caregivers

Luo

Chen

et al. 2021

Psycho-Oncology

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Objective Colorectal cancer (CRC) survivors have reported a number of concerns and unmet needs after treatment completion. This paper aims to explore existing survivorship interventions after CRC treatment according to the American Cancer Society CRC Survivorship Care Guidelines, to identify study gaps, and provide valuable evidence directing future research. Methods Five electronic databases, including CINAHL, PsycINFO, Embase, PubMed, and Cochrane Library databases from 2005 to October 2020, were systematically searched to identify English or Chinese literature on CRC post‐treatment survivorship interventions. Manual searching through the articles' references lists was also conducted. Results Thirty studies met the criteria, and focused on addressing issues in four CRC Survivorship Care Guidelines domains. Several issues for CRC surveillance programmes remain to be explored. Regarding the long‐term physical and psychosocial effects of CRC treatment, we found mounting evidence for various interventions to solve ostomy issues and improve distress/depression/anxiety, strong evidence for exercise to improve fatigue, and limited evidence in addressing CRC patient sexual concerns. For health promotion, high‐quality evidence was found for exercises to improve cardiopulmonary fitness, metabolism, tumour‐related biomarkers, and short‐term improvement in physical fitness and QOL. Emerging evidence was found for a survivorship care plan to improve patient perceptions of care coordination. Conclusions Further refinements based on the existing evidence, and the development of comprehensive CRC survivorship care comprising multiple essential survivorship components, are required. Furthermore, considering both survivor and caregiver cancer survivorship needs, future research may optimise the care delivered, and help survivors and their families live better with cancer.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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A literature review of post‐treatment survivorship interventions for colorectal cancer survivors and/or their caregivers

Luo

Chen

et al. 2021

Psycho-Oncology

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“…Colorectal cancer is the most common cancer type in the world after lung and BrCa ( 51 ). The surgical approach of managing colorectal cancer is limited for cases with localized tumors but not feasible in early stage tumors and metastatic tumors.…”

Section: Examples Of Pretargeted Theranosticsmentioning

confidence: 99%

Theranostic Pretargeting Drug Delivery and Imaging Platforms in Cancer Precision Medicine

Hapuarachchige

Artemov

2020

Front. Oncol.

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Theranostics are nano-size or molecular-level agents serving for both diagnosis and therapy. Structurally, they are drug delivery systems integrated with molecular or targeted imaging agents. Theranostics are becoming popular because they are targeted therapeutics and can be used with no or minimal changes for diagnostic imaging to aid in precision medicine. Thus, there is a close relation between theranostics and image-guided therapy (IGT), and theranostics are actually a subclass of IGT in which both therapeutic and imaging functionalities are attributed to a single platform. An important theranostics strategy is biological pretargeting. In pretargeted IGT, first, the target is identified by a target-specific natural or synthetic bioligand followed by a nano-scale or molecular drug delivery component, which form therapeutic clusters by in situ conjugation reactions. If pretargeted drug delivery platforms are labeled with multimodal imaging probes, they can be used as theranostics for both diagnostic imaging and therapy. Optical and nuclear imaging techniques have mostly been used in proof-of-concept studies with pretargeted theranostics. The concept of pretargeting in theranostics is comparatively novel and generally requires a confirmed overexpression of surface receptors on targeted cells/tissue. In addition, the receptors should have natural or synthetic bioligands to be used as pretargeting components. Therefore, applications of pretargeting theranostics are still limited to several cancer types, which overexpress cell-surface markers on the target cancer cells. In this review, recent discoveries of pretargeting theranostics in breast, ovarian, prostate, and colorectal cancers are discussed to highlight main strengths and potential limitations the strategy.

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