Physical activity and performance in older persons with musculoskeletal impairment: results of a pilot study with 9-month follow-up

Cecchi, Francesca; Pasquini, Guido; Chiti, M.; Lova, Raffaele Molino; Enock, E.; Nofri, Giacomo; Paperini, Anita; Conti, Andrea A.; Mannoni, Alessandro; Macchi, Claudio

doi:10.1007/bf03325219

Cited by 4 publications

(1 citation statement)

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“…Regarding comorbidities, a multidomain prolonged intervention including diet, physical exercise, cognitive training, and vascular risk factors monitoring could reduce the onset of new comorbidities, as already demonstrated in a younger population (Marengoni et al, 2018). It is then necessary to investigate whether similar or different multidimensional interventions may prove effective also in the last period of life, in preventing/postponing disability (Cecchi et al, 2009) and in effectively prolonging lifespan (Ackermann, 2018). Moreover, it has been suggested that polypharmacy per se increases the risk of mortality (Błeszyńska et al, 2020) as well as of disability (Cecchi et al, 2020) due to the high risk of negative drug interaction and to the higher vulnerability to side effects in the elderly population.…”

Section: Discussionmentioning

confidence: 99%

Predictors of Mortality in 433 Nonagenarians Inside the Mugello Study: A 10 Years Follow-Up Study

et al. 2022

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Objective to identify the predictors of mortality in a cohort of nonagenarians inside the “Mugello study” after 10 years follow-up. Methods Information on sociodemographic data, cognitive and functional status, lifestyle, medical history, and drug use was collected from 433 non-selected participants aged 90-99 years, living in the Mugello area (Italy). Participants were followed over 10 years and their dates of death were retrieved from the municipal registers. Cox regression analysis was used to determine significant potential prognostic factors. Results The mortality rate was 96.5%. Cox proportional hazards analysis showed that a lower cognitive status was significantly associated with higher mortality as well as a poorer functional status, a higher comorbidity, and a higher number of drugs consumption. Discussion Impaired cognitive function, loss of functional independence, higher comorbidity, and higher drugs intake were the stronger predictors of mortality.

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Section: Discussionmentioning

confidence: 99%

Predictors of Mortality in 433 Nonagenarians Inside the Mugello Study: A 10 Years Follow-Up Study

et al. 2022

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Supervised Versus Unsupervised Exercise for the Improvement of Physical Function and Well-Being Outcomes in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Gómez-Redondo,

Valenzuela,

Morales

et al. 2024

Sports Med

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Background Unsupervised exercise intervention (UNSUP) appears to be a practical and beneficial strategy for older adults, although its feasibility and effectiveness compared to supervised exercise intervention (SUP) remains unknown. We aimed to compare the safety, attendance/adherence rates, and effectiveness of SUP versus UNSUP on physical function and well-being outcomes in older adults. Methods A systematic search was conducted in PubMed, Web of Science, CINAHL, SPORTDiscus, and APA PsycINFO up to September 2022 for randomized controlled trials comparing SUP versus UNSUP in older adults (≥ 60 years). Safety and attendance/adherence rates were registered as indicators of feasibility, and meta-analyses were performed for physical function and well-being outcomes. Sub-analyses were performed for those studies that applied a similar intervention in both groups and for those studies where participants performed ≥ 66% of the sessions in the assigned condition. Results Thirty-four studies were included (n = 2830). No serious adverse events were reported, with similar attendance rates (81%) for both SUP and UNSUP. Compared with UNSUP, SUP induced significant higher benefits on knee extension strength (standardized mean difference (SMD) = 0.18, p = 0.002), sit-to-stand test (STS, SMD = 0.25, p = 0.050), timed-up-and-go test (TUG, SMD = 0.21, p = 0.035), usual gait speed (SMD = 0.29, p = 0.026), lean mass (mean difference = 1.05 kg, p < 0.001) and health-related quality of life (HRQoL, SMD = 0.21, p = 0.035), albeit only knee extension strength remained significant in sensitivity analyses. Sub-analyses revealed superior benefits of SUP on knee extension strength when only considering those studies that applied a similar intervention in both SUP and UNSUP groups. However, no significant benefits were found for the remaining outcomes. Beneficial effects of SUP over UNSUP were also observed for knee extension strength, STS, functional reach test, TUG, usual gait speed, lean mass, and HRQoL when separately analyzing those studies in which participants performed ≥ 66% of the sessions in the assigned condition. Conclusions Current evidence suggests that both SUP and UNSUP programs are safe and could exert benefits on physical function and HRQoL. However, despite being associated with similar attendance rates, SUP might offer some additional benefits, although further high-quality research (i.e., accounting for confounding factors such as presence of supervised sessions in UNSUP or vice versa, as well as equating the exercise dose) is necessary to confirm these findings. PROSPERO Registration Number CRD42022326420.

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Disparities in Health-Risk Behaviors, Preventive Health Care Utilizations, and Chronic Health Conditions for People With Disabilities: The Korean National Health and Nutrition Examination Survey

Ko¹,

Lee²,

Cho³

et al. 2011

Archives of Physical Medicine and Rehabilitation

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Physical activity and performance in older persons with musculoskeletal impairment: results of a pilot study with 9-month follow-up

Abstract: In this physically impaired sample, a 3- month exercise program, compared with unsupervised regular walking, was associated with improved performance, fitness and vitality after discharge, and to delayed physical decline in the next 6-month follow-up.

Cited by 4 publications

References 23 publications

Predictors of Mortality in 433 Nonagenarians Inside the Mugello Study: A 10 Years Follow-Up Study

Predictors of Mortality in 433 Nonagenarians Inside the Mugello Study: A 10 Years Follow-Up Study

Supervised Versus Unsupervised Exercise for the Improvement of Physical Function and Well-Being Outcomes in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Disparities in Health-Risk Behaviors, Preventive Health Care Utilizations, and Chronic Health Conditions for People With Disabilities: The Korean National Health and Nutrition Examination Survey

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