Physical Activity, All-Cause and Cardiovascular Mortality, and Cardiovascular Disease

Abstract

Purpose.-Conduct a systematic umbrella review to evaluate the relationship of physical activity (PA) with all-cause mortality, cardiovascular mortality, and incident cardiovascular disease; to evaluate the shape of the dose-response relationships; and to evaluate these relationships relative to the 2008 Physical Activity Guidelines Advisory Committee (PAGAC) Report. Methods.-Primary search encompassing 2006-March, 2018 for existing systematic reviews, meta-analyses, and pooled analyses reporting on these relationships. Graded the strength of evidence using a matrix developed for the PAGAC.

Update on cardiovascular prevention in clinical practice: A position paper of the European Association of Preventive Cardiology of the European Society of Cardiology

“…There is an inverse dose-response relationship between moderate-vigorous aerobic PA and all-cause and cardiovascular mortality and incident CVD: CAD, ischaemic stroke and HF. 107 Benefits start to accumulate from moving to being inactive to perform PA at a lower amount, and increases with the higher amount of PA. 108 In healthy adults 150 to 300 minutes a week of moderate intensity PA or 75 to 150 minutes of vigorous intensity PA or an equivalent combination thereof (a volume of 500-1000 metabolic equivalent minutes per week), reduces the risk of all causes of mortality. 109 Higher volumes of PA through higher intensity, greater frequency or longer duration contribute to risk reduction, but greater increases in PA are required to obtain a modest gain in benefit.…”

“…PA amounts up to three to five times the recommendation shows no evidence in mortality risk. 107 There is now evidence that bouts of any duration, even less than 10 minutes, are effective and count for the daily/weekly volume target of PA. 84,110 There is moderate evidence that high intensity interval training can improve insulin sensitivity, BP and body composition similarly to aerobic continuous PA training, especially in overweight or obese adults. 111 The improvements in risk factor control are more likely to occur in adults at greater risk of CVD and DM.…”

Prevention of excessive exercise‐induced adverse effects in rats withBacillus subtilisBSB3

“…Regular moderate exercise reduces the incidence of inflammatory diseases, has protective effect against cancer, gastrointestinal disorders and obesity (Martin 2011;Kruk and Czerniak 2013;Allen et al 2018). Physical activity is associated with a marked decrease in all-cause mortality, cardiovascular mortality, cardiovascular disease (Kraus et al 2019) and with a delay in onset of dementia in elderly persons (Larson et al 2006). However, recent data suggest high level of physical activity results in increased risk of early mortality (Coenen et al 2018).…”

Recomendaciones de actividad física: un mensaje para el profesional de la salud

“…También es un estímulo importante a mensajes como subir escaleras, estacionar más lejos y caminar siempre que sea posible. Debido a las evidencias de disminución de mortalidad por todas las causas y por ECV (aterosclerótica, enfermedad coronaria, accidente cerebrovascular isquémico y falla cardíaca) se aumentó la cantidad mínima de AFMV, aunque los resultados ya son evidentes inclusive con un tercio de la recomendación (27) . Cumplir con las guías de 2008 de media hora al día, reduce el riesgo de mortalidad por todas las causas a alrededor de 75 % del máximo beneficio.…”