Phylogeographic history of mitochondrial haplogroup <scp>J</scp> in <scp>Scandinavia</scp>

Kristjansson, Dana; Schurr, Theodore G.; Bohlin, Jon; Jugessur, Astanand

doi:10.1002/ajpa.24666

Cited by 2 publications

(1 citation statement)

References 87 publications

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“…Haplogroup J is believed to have originated approximately 45,000 years ago, likely in West Asia, specifically the Near East or Caucasus regions. Interestingly, recent research by Kristjansson et al revealed that mitochondrial DNA haplogroup J is also the third most frequent haplogroup in modern-day Scandinavia, despite not originating there [24]. Within our study, the majority of haplogroup J1 was represented by J1a (frequency of 11.24%), with J1b (including J1b1b1) being the more prevalent subclade at a frequency of 7.52%.…”

Section: Results and Discussion: Mt-dna Haplogroup Frequencysupporting

confidence: 52%

Large-Scale Assessment of the Iranian population structure of Mitochondrial and Y-chromosome Haplogroups

Mazaheri,

Ghahremani,

Babazadeh

et al. 2024

Preprint

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The Iranian plateau, strategically positioned as a corridor for population diffusion across Eurasia, holds a pivotal role in elucidating the dynamics of human migrations originating from Africa around 60,000 years ago. Both prehistoric and historic movements of populations between Africa, Asia, and Europe may have been influenced by the unique geographical features of the Iranian plateau. Iran boasts ancient cultures and urban settlements predating some of the earliest civilizations, including the Neolithic revolution in neighboring Mesopotamia. Spanning from the Balkans and Egypt in the west to the Indus Valley in Pakistan and northern India in the southeast, the Iranian plateau encompasses a vast area characterized by incredible ethnocultural diversity. This region served as the origin for numerous mt-DNA/Y-DNA haplogroups that expanded to West Asia, Europe, Siberia, Central Asia, and South Asia. By examining both maternal and paternal haplogroups within the Iranian context, we aim to contribute to the broader narrative of human dispersals and elucidate the role those specific regions, such as the Iranian plateau, played in shaping the observed genetic diversity today. Due to the lack of comprehensive studies on mt-DNA /Y-DNA haplogroups in the Iranian population, our study sought to uncover the distribution of haplogroups among Iranian peoples using a large sample size. Our analysis focused on the frequency of ancestral haplogroups in Iran through the examination of large-scale whole-exome sequencing (WES) and SNP microarray data from 18,184 individuals. In our study, we observed 24 mt-DNA super haplogroups in the Iranian population, with the most common haplogroups belonging to West-Eurasian lineages U (20.73%), H (18.84%), J (12.10%), HV (9.22%), and T (8.98%), collectively comprising 69.70% of all Iranian samples. Notably, subclades J1 and U7 emerged as the two most frequent subclades, with frequencies of 11.24% and 7.30%, respectively. We also revealed the presence of 14 distinct Y-DNA haplogroups, with J, R, G, T, and Q emerging as the five predominant lineages. Notably, J2 (including J-L26) exhibited the highest frequency at 35.64%, followed by R1a at 14.68%. also, The detected mtDNA and Y-chromosome haplogroups were clustered into distinct groups that confirmed the heterogenicity of the Iranian population because of various factors including geographic or linguistic ethnic groups. Keywords: Iranian Plateau, mt-DNA haplogroup, Y-DNA haplogroup, Whole Exome Sequencing (WES), SNP microarray

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Section: Results and Discussion: Mt-dna Haplogroup Frequencysupporting

confidence: 52%

Large-Scale Assessment of the Iranian population structure of Mitochondrial and Y-chromosome Haplogroups

Mazaheri,

Ghahremani,

Babazadeh

et al. 2024

Preprint

View full text Add to dashboard Cite

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Phylogeographic history of mitochondrial haplogroup J in Scandinavia

Kristjansson

Schurr

Bohlin

et al. 2022

American Journal of Biological Anthropology

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Background: Mitochondrial DNA haplogroup J is the third most frequent haplogroup in modern-day Scandinavia, although it did not originate there. To infer the genetic history of haplogroup J in Scandinavia, we examined worldwide mitogenome sequences using a maximum-likelihood phylogenetic approach.Methods: Haplogroup J mitogenome sequences were gathered from GenBank (n = 2245) and aligned against the ancestral Reconstructed Sapiens Reference Sequence. We also analyzed haplogroup J Viking Age sequences from the European Nucleotide Archive (n = 54). Genetic distances were estimated from these data and projected onto a maximum likelihood rooted phylogenetic tree to analyze clustering and branching dates.Results: Haplogroup J originated approximately 42.6 kya (95% CI: 30.0-64.7), with several of its earliest branches being found within the Arabian Peninsula and Northern Africa. J1b was found most frequently in the Near East and Arabian Peninsula, while J1c occurred most frequently in Europe. Based on phylogenetic dating, subhaplogroup J1c has its early roots in the Mediterranean and Western Balkans. Otherwise, the majority of the branches found in Scandinavia are younger than those seen elsewhere, indicating that haplogroup J dispersed relatively recently into Northern Europe, most plausibly with Neolithic farmers.Conclusions: Haplogroup J appeared when Scandinavia was transitioning to agriculture over 6 kya, with J1c being the most common lineage there today. Changes in the distribution of haplogroup J mtDNAs were likely driven by the expansion of farming from West Asia into Southern Europe, followed by a later expansion into Scandinavia, with other J subhaplogroups appearing among Scandinavian groups as early as the Viking Age.

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Phylogeographic history of mitochondrial haplogroup J in Scandinavia

Cited by 2 publications

References 87 publications

Large-Scale Assessment of the Iranian population structure of Mitochondrial and Y-chromosome Haplogroups

Large-Scale Assessment of the Iranian population structure of Mitochondrial and Y-chromosome Haplogroups

Phylogeographic history of mitochondrial haplogroup J in Scandinavia

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