Photoredox-Catalyzed C(sp2)–H Bond Functionalization Reactions: A Short Account

Abstract

Photoredox catalysis gets rapid development and wide application in the chemical community during the past several years because of its advantages on reaction engineering. Since 2016, Loh et al. started their research on photoredox catalyzed reaction transformations, including -C(sp2)–H fluoroalkylation, alkylation, and acylation of enamides, C(sp2)–H phosphorylation of alkenes converted from alcohols, C(sp2)–H bromination and alkylation of (hetero)arenes. These transformations provided a broad diversity of structural differences on the C(sp2)-H bond, bearing extensive range of functional groups and showcased appealing further synthetic utilities. 1 Introduction 2 Photoredox-Catalyzed -C(sp2)–H Functionalization of enamides 3 Photoredox-Catalyzed C(sp2)–H Functionalization of alkenes 4 Photoredox-Catalyzed C(sp2)–H Functionalization of (hetero)arenes 5 Conclusion

Photooxidative Reaction of β-Oxoamides with Amines for the Synthesis of Pyrrolin-4-ones under External Photocatalyst-Free Conditions

“…Enamines are readily available and versatile starting materials for heterocycle synthesis, such as 1,2,3-triazoles, imidazoles, pyridines, thiazoles, azirines, and indoles . Among these reports, the synthesis of pyrrolin-4-ones is of particular interest in the synthetic community.…”