Photoprotection

Kullavanijaya, Prisana; Lim, Henry W.

doi:10.1016/j.jaad.2004.07.063

Cited by 334 publications

(291 citation statements)

References 242 publications

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“…However, α-tocopherol acetate has not shown efficacy even though it is widely used in commercial sunscreen products. α-tocopherol acetate has a lower photoprotective effect due to its absorption over a lower UVB range than α-tocopherol once absorbed into the skin [34].…”

Section: Tocopherolmentioning

confidence: 99%

Cosmeceuticals Derived from Bioactive Substances Found in Marine Algae

Agatonović-Kuštrin

Morton²

2013

Oceanography

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Section: Tocopherolmentioning

confidence: 99%

Cosmeceuticals Derived from Bioactive Substances Found in Marine Algae

Agatonović-Kuštrin

Morton²

2013

Oceanography

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“…These reactions can also trigger oxidative stress in cells by promoting formation of reactive oxygen species and initiating carcinogenesis by causing damage to DNA, proteins and lipids; such reactions are thus responsible for structural and functional disorders [1,3,4].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Functional Stability of Photoprotective Formulations Containing Rutin Succinate

2017

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Abstract:The aim of this study was to evaluate physicochemical and functional stability of two different self-emulsified oil/water (O/W) systems. Each system contained 0.4% w/w rutin succinate, which was associated or not with the photo-unstable chemical (7.5% w/w of 2-ethylhexyl 4-methoxycinnamate and 3.0% w/w of 2-hydroxy-4-methoxybenzophenone) or physical filters (3.0% w/w titanium dioxide). A Normal Stability Test was carried out with the formulations containing rutin succinate (S) associated either with sunscreens (MS) or not (M) for 90 days. The formulation systems were assessed for organoleptic, functional, physicochemical and rheological behavior parameters. The MS formulation was found to be homogenous and had no significant alterations of pH, hysteresis area, antiradical activity or Sun Protection Factor values. Such stability was mainly observed when the formulation was incorporated into base cream A. The ability of chemical filters to resist degradation caused by UV radiation in the presence of rutin succinate preventing lipid peroxidation by entrapment of initiator radicals is a mechanism that might explain the results. The combination of rutin succinate to chemical filters improved formulation functionality, as it led to a more stable formulation which maintained the effectiveness of the added sunscreens. Consumer acceptance could be improved, considering that film formation and rheological spreadability characteristics of the tested formulation are better than those of traditional formulations.

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“…UVA causes DNA damage via an oxidative process increasing the level of reactive oxygen species accompanied by cell membrane lipid peroxidation eventuating in cutaneous inflammation (Kullavanijaya, Lim, 2005).…”

Section: Introductionmentioning

confidence: 99%

Development of O/W emulsions containing Euterpe oleracea extract and evaluation of photoprotective efficacy

Daher

Fontes

Rodrigues

et al. 2014

Braz. J. Pharm. Sci.

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Euterpe oleracea Mart. is a palm tree popularly known as açai, which is primarily found in northern Brazil. The açai's fruits contain anthocyanins, a class of polyphenols to which antioxidant properties have been attributed. The aim of this work was to develop O/W sunscreens emulsions containing açai glycolic extract (AGE) and to evaluate both their physical stability and photoprotective efficacy. Emulsions containing AGE and sunscreens were formulated using different types and concentrations of polymeric surfactant (acrylates/C 10-30 alkyl acrylate crosspolymer and sodium polyacrylate). The influence of two rheology modifiers (polyacrylamide (and) C13-14/isoparaffin (and) Laureth-7 and Carbomer) on the stability was also investigated. Physical stability was evaluated by preliminary and accelerated studies. Emulsions with 1.0% sodium polyacrylate were stable and exhibited non-newtonian pseudoplastic behavior and thixotropy. Photoprotective efficacy was evaluated by in vivo Sun Protection Factor (SPF) and determination of Protection Factor of UVA (PF-UVA). When AGE was added to the sunscreen emulsion, no significant increase in the in vivo SPF value was observed. The emulsion containing AGE showed PF-UVA = 14.97, 1.69 of the SPF/PF-UVA ratio and a critical wavelength value of 378 nm, and may therefore be considered a sunscreen with UVA and UVB protection. Euterpe oleracea Mart. é uma palmeira popularmente conhecida como açaí, encontrada no norte do Brasil. O fruto do açaí apresenta em sua composição antocianinas, uma classe de polifenóis à qual é atribuída propriedade antioxidante. Os objetivos desse trabalho foram desenvolver emulsões fotoprotetoras O/A contendo extrato glicólico de açaí (AGE), avaliar a estabilidade física e avaliar a eficácia fotoprotetora. Emulsões contendo AGE e filtros solares foram formuladas utilizando diferentes tipos e concentrações de tensoativo polimérico (acrilates/C 10-30 alquil acrilato polímero cruzado e polilacrilato sódico). A influência de dois modificadores reológicos (poliacrilamida (e) C13-14/isoparafina (e) Laureth-7 e Carbomer) na estabilidade foi avaliada. A estabilidade física das emulsões foi avaliada por meio de estudos de estabilidade preliminar e acelerada. Emulsões com 1,0% poliacrilato sódico foram estáveis, exibiram comportamento não-newtoniano pseudoplástico e tixotrópico. A eficácia fotoprotetora foi avaliada pelo teste in vivo de Fator de Proteção Solar (FPS) e pela determinação do Fator de Proteção UVA (FP-UVA). Quando adicionado o AGE na emulsão contendo filtros solares, não se observou aumento significativo no valor do FPS. A emulsão contendo o AGE apresentou FP-UVA=14,97, a razão FPS/ FP-UVA = 1,69 e o comprimento de onda crítico igual a 378 nm, podendo ser considerado um protetor solar com proteção UVA e UVB. Unitermos:Emulsão O/A/desenvolvimento. Euterpe oleracea/farmacognosia. Euterpe oleracea/extrato glicólico/eficácia fotoprotetora. Protetores Solares/desenvolvimento. Fator de Proteção Solar.

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Photoprotection

Abstract: At the conclusion of this learning activity, participants should be able to provide an overview of all aspects of photoprotection.

Cited by 334 publications

References 242 publications

Cosmeceuticals Derived from Bioactive Substances Found in Marine Algae

Cosmeceuticals Derived from Bioactive Substances Found in Marine Algae

Assessment of Functional Stability of Photoprotective Formulations Containing Rutin Succinate

Development of O/W emulsions containing Euterpe oleracea extract and evaluation of photoprotective efficacy

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