Photophysical studies of the pheophorbide a dimer

Eichwurzel, I.; Stiel, H.; Röder, Beate

doi:10.1016/s1011-1344(00)00016-6

Cited by 76 publications

(65 citation statements)

References 21 publications

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“…However, products of chlorophyll degradation might affect the red and far-red emissions. Of particular note is pheophorbide a, which absorbs UV and red light and fluoresces red and far-red (Matile et al, 1999;Eichwurzel et al, 2000;Ashby et al, 2003).…”

Section: Discussionmentioning

confidence: 99%

Fluorescence indices for monitoring the ripening of tomatoes in pre- and postharvest phases

Hoffmann

Noga

Hunsche

2015

Scientia Horticulturae

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Section: Discussionmentioning

confidence: 99%

Fluorescence indices for monitoring the ripening of tomatoes in pre- and postharvest phases

Hoffmann

Noga

Hunsche

2015

Scientia Horticulturae

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“…5(a)). The free PhA in formamide had a strong absorption at 667 nm, indicating that the molecule exists in a monomeric form in formamide (Eichwurzel, Stiel, & Roder, 2000). However, the Q-band absorption of free PhA in PBS shifted toward longer wavelengths (e.g., 683 nm) compared with that of free PhA in formamide.…”

Section: Spectrometric Characteristics Of the Hpha/pcar Nanocomplexmentioning

confidence: 97%

Polyelectrolyte nanocomplex formation of heparin-photosensitizer conjugate with polymeric scavenger for photodynamic therapy

Cho

Kim³

et al. 2015

Carbohydrate Polymers

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“…Methyl pheophorbide-a (Mpa) and methyl pyro-pheophorbide-a (Mppa) as chlorin analogues are ideal materials for photodynamic therapy due to their advantages of long absorption wavelength (>667 nm), low dark toxicity, high molar extinction coefficient and high rate of fluorescence quantum yield [23]. C-3, 5, 7, 10, 12, 13, 17, 20 of MPPa are high-active reactive sites and are easily modified for the development of new photosensitizers.…”

Section: Introductionmentioning

confidence: 99%

A Novel Photosensitizer 31,131-phenylhydrazine -Mppa (BPHM) and Its in Vitro Photodynamic Therapy against HeLa Cells

Tan

Cheng

et al. 2016

Molecules

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Photodynamic therapy (PDT) has attracted widespread attention due to its potential in the treatment of various cancers. Porphyrinic pyropheophorbide-a (PPa) has been shown to be a potent photosensitizer in PDT experiments. In this paper, a C-3 1 ,13 1 bisphenylhydrazone modified methyl pyropheophorbide-a (BPHM) was designed and synthesized with the consideration that phenylhydrazone structure may extend absorption wavelength of methyl pyro-pheophorbide-a (Mppa), and make the photosensitizer potential in deep tumor treatment. The synthesis, spectral properties and in vitro photodynamic therapy (PDT) against human HeLa cervical cancer cell line was studied. Methyl thiazolyl tetrazolium (MTT) assay showed the title compound could achieve strong inhibition of cervical cancer cell viability under visible light (675 nm, 25 J/cm 2 ). Cell uptake experiments were performed on HeLa cells. Morphological changes were examined and analyzed by fluorescent inverted microscope. In addition, the mechanism of the photochemical processes of PDT was investigated, which showed that the formation of singlet oxygen after treatment with PDT played a moderate important role.

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Photophysical studies of the pheophorbide a dimer

Cited by 76 publications

References 21 publications

Fluorescence indices for monitoring the ripening of tomatoes in pre- and postharvest phases

Fluorescence indices for monitoring the ripening of tomatoes in pre- and postharvest phases

Polyelectrolyte nanocomplex formation of heparin-photosensitizer conjugate with polymeric scavenger for photodynamic therapy

A Novel Photosensitizer 31,131-phenylhydrazine -Mppa (BPHM) and Its in Vitro Photodynamic Therapy against HeLa Cells

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